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Murcko scaffold

Ring system with 5 rings and 30 atoms

36 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
30
Chemicals
36
With full pages
1
Scaffold SMILES

O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1cc2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1cc2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 36 of 36 chemicals

Devazepide chemical structure, C25H20N4O2, CAS 103420-77-5
Devazepide
CAS 103420-77-5C25H20N4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide chemical structure, C25H19FN4O2, CAS 103343-58-4
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
CAS 103343-58-4C25H19FN4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-5-methoxy-1H-indole-2-carboxamide chemical structure, C26H21FN4O3, CAS 1062652-28-1
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-5-methoxy-1H-indole-2-carboxamide
CAS 1062652-28-1C26H21FN4O3
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1-methyl-1H-indole-2-carboxamide chemical structure, C26H21FN4O2, CAS 103343-59-5
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1-methyl-1H-indole-2-carboxamide
CAS 103343-59-5C26H21FN4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-hydroxy-1H-indole-2-carboxamide chemical structure, C25H19FN4O3, CAS 2624125-69-3
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-hydroxy-1H-indole-2-carboxamide
CAS 2624125-69-3C25H19FN4O3
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1-(prop-2-yn-1-yl)-1H-indole-2-carboxamide chemical structure, C28H21FN4O2, CAS 2624115-82-6
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1-(prop-2-yn-1-yl)-1H-indole-2-carboxamide
CAS 2624115-82-6C28H21FN4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-6-hydroxy-1-methyl-1H-indole-2-carboxamide chemical structure, C26H21FN4O3, CAS 2624122-78-5
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-6-hydroxy-1-methyl-1H-indole-2-carboxamide
CAS 2624122-78-5C26H21FN4O3
5-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-methyl-1H-indole-2-carboxamide chemical structure, C26H20F2N4O2, CAS 2624114-94-7
5-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-methyl-1H-indole-2-carboxamide
CAS 2624114-94-7C26H20F2N4O2
7-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-methyl-1H-indole-2-carboxamide chemical structure, C26H20F2N4O2, CAS 2624126-04-9
7-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-methyl-1H-indole-2-carboxamide
CAS 2624126-04-9C26H20F2N4O2
5-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide chemical structure, C25H18ClFN4O2, CAS 2624118-54-1
5-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
CAS 2624118-54-1C25H18ClFN4O2
5-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide chemical structure, C25H18F2N4O2, CAS 2624122-73-0
5-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
CAS 2624122-73-0C25H18F2N4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-5-methyl-1H-indole-2-carboxamide chemical structure, C26H21FN4O2, CAS 2624122-04-7
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-5-methyl-1H-indole-2-carboxamide
CAS 2624122-04-7C26H21FN4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-methoxy-1H-indole-2-carboxamide chemical structure, C26H21FN4O3, CAS 2624122-86-5
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-methoxy-1H-indole-2-carboxamide
CAS 2624122-86-5C26H21FN4O3
5,6-Difluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide chemical structure, C25H17F3N4O2, CAS 2624119-05-5
5,6-Difluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
CAS 2624119-05-5C25H17F3N4O2
6-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide chemical structure, C25H18F2N4O2, CAS 2624122-08-1
6-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
CAS 2624122-08-1C25H18F2N4O2
4-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide chemical structure, C25H18ClFN4O2, CAS 2624123-23-3
4-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
CAS 2624123-23-3C25H18ClFN4O2
4-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide chemical structure, C25H18F2N4O2, CAS 2624116-02-3
4-Fluoro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
CAS 2624116-02-3C25H18F2N4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-methyl-1H-indole-2-carboxamide chemical structure, C26H21FN4O2, CAS 2624123-28-8
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4-methyl-1H-indole-2-carboxamide
CAS 2624123-28-8C26H21FN4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-6-methyl-1H-indole-2-carboxamide chemical structure, C26H21FN4O2, CAS 2624121-54-4
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-6-methyl-1H-indole-2-carboxamide
CAS 2624121-54-4C26H21FN4O2
3-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide chemical structure, C25H18ClFN4O2, CAS 2624116-09-0
3-Chloro-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
CAS 2624116-09-0C25H18ClFN4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4,7-dimethyl-1H-indole-2-carboxamide chemical structure, C27H23FN4O2, CAS 2624125-16-0
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-4,7-dimethyl-1H-indole-2-carboxamide
CAS 2624125-16-0C27H23FN4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-methyl-1H-indole-2-carboxamide chemical structure, C26H21FN4O2, CAS 2624121-95-3
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-methyl-1H-indole-2-carboxamide
CAS 2624121-95-3C26H21FN4O2
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-7-methyl-1H-indole-2-carboxamide chemical structure, C26H21FN4O2, CAS 2624125-30-8
N-[5-(2-Fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-7-methyl-1H-indole-2-carboxamide
CAS 2624125-30-8C26H21FN4O2
1-Ethyl-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide chemical structure, C27H23FN4O2, CAS 2624117-60-6
1-Ethyl-N-[5-(2-fluorophenyl)-1-methyl-2-oxo-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide
CAS 2624117-60-6C27H23FN4O2