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Murcko scaffold

2-(1,4-Dioxaspiro[4.5]decan-8-yl)pyridine scaffold

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
20
With full pages
1
Scaffold SMILES

c1ccc(C2CCC3(CC2)OCCO3)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(1,4-Dioxaspiro[4.5]decan-8-yl)pyridine page
Murcko scaffold c1ccc(C2CCC3(CC2)OCCO3)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

4-Hydroxy-4-(2-pyridyl)cyclohexanone ethylene acetal chemical structure, C13H17NO3, CAS 103319-04-6
4-Hydroxy-4-(2-pyridyl)cyclohexanone ethylene acetal
CAS 103319-04-6C13H17NO3
2-(1,4-Dioxaspiro[4.5]decan-8-yl)pyridine chemical structure, C13H17NO2, CAS 117960-48-2
2-(1,4-Dioxaspiro[4.5]decan-8-yl)pyridine
CAS 117960-48-2C13H17NO2
8-(5-Bromopyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol chemical structure, C13H16BrNO3, CAS 708274-37-7
8-(5-Bromopyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol
CAS 708274-37-7C13H16BrNO3
8-{5-[(Dimethylamino)methyl]pyridin-2-yl}-1,4-dioxaspiro[4,5]decan-8-ol chemical structure, C16H24N2O3, CAS 708273-79-4
8-{5-[(Dimethylamino)methyl]pyridin-2-yl}-1,4-dioxaspiro[4,5]decan-8-ol
CAS 708273-79-4C16H24N2O3
8-(Pyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carbonitrile chemical structure, C14H16N2O2, CAS 1006685-96-6
8-(Pyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carbonitrile
CAS 1006685-96-6C14H16N2O2
[8-(Pyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-yl]methanol chemical structure, C14H19NO3, CAS 1006685-98-8
[8-(Pyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-yl]methanol
CAS 1006685-98-8C14H19NO3
Methyl 5-fluoro-6-(1,4-dioxaspiro[4.5]decan-8-yl)picolinate chemical structure, C15H18FNO4, CAS 1210419-07-0
Methyl 5-fluoro-6-(1,4-dioxaspiro[4.5]decan-8-yl)picolinate
CAS 1210419-07-0C15H18FNO4
8-Hydroxy-8-(5-methoxy-2-pyridyl)-1,4-dioxaspiro[4.5]decane chemical structure, C14H19NO4, CAS 1228652-19-4
8-Hydroxy-8-(5-methoxy-2-pyridyl)-1,4-dioxaspiro[4.5]decane
CAS 1228652-19-4C14H19NO4
6-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrile chemical structure, C14H16N2O3, CAS 708273-67-0
6-(8-Hydroxy-1,4-dioxaspiro[4.5]dec-8-yl)nicotinonitrile
CAS 708273-67-0C14H16N2O3
3-Hydroxy-6-(8-hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)pyridine chemical structure, C13H17NO4, CAS 713526-59-1
3-Hydroxy-6-(8-hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)pyridine
CAS 713526-59-1C13H17NO4
6-(1,4-Dioxaspiro[4.5]decan-8-yl)pyridin-3-ol chemical structure, C13H17NO3, CAS 1516942-10-1
6-(1,4-Dioxaspiro[4.5]decan-8-yl)pyridin-3-ol
CAS 1516942-10-1C13H17NO3
8-(2-Pyridinyl)-1,4-dioxaspiro[4.5]decane-8-carboxamide chemical structure, C14H18N2O3, CAS 1862256-87-8
8-(2-Pyridinyl)-1,4-dioxaspiro[4.5]decane-8-carboxamide
CAS 1862256-87-8C14H18N2O3
8-(2-Pyridinyl)-1,4-dioxaspiro[4.5]decan-8-amine chemical structure, C13H18N2O2, CAS 1862256-89-0
8-(2-Pyridinyl)-1,4-dioxaspiro[4.5]decan-8-amine
CAS 1862256-89-0C13H18N2O2
N-[8-(2-Pyridinyl)-1,4-dioxaspiro[4.5]dec-8-yl]carbamic acid methyl ester chemical structure, C15H20N2O4, CAS 1862256-88-9
N-[8-(2-Pyridinyl)-1,4-dioxaspiro[4.5]dec-8-yl]carbamic acid methyl ester
CAS 1862256-88-9C15H20N2O4
[8-(Pyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-yl]methanamine chemical structure, C14H20N2O2, CAS 2344677-50-3
[8-(Pyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-yl]methanamine
CAS 2344677-50-3C14H20N2O2
Ethyl 8-(pyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate chemical structure, C16H21NO4, CAS 2708292-45-7
Ethyl 8-(pyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate
CAS 2708292-45-7C16H21NO4
Ethyl 8-(5-methylpyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate chemical structure, C17H23NO4, CAS 2708281-51-8
Ethyl 8-(5-methylpyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate
CAS 2708281-51-8C17H23NO4
Ethyl 8-(5-fluoropyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate chemical structure, C16H20FNO4, CAS 2708278-08-2
Ethyl 8-(5-fluoropyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate
CAS 2708278-08-2C16H20FNO4
Ethyl 8-(5-(trifluoromethyl)pyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate chemical structure, C17H20F3NO4, CAS 2708292-42-4
Ethyl 8-(5-(trifluoromethyl)pyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate
CAS 2708292-42-4C17H20F3NO4
Ethyl 8-(5-methoxypyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate chemical structure, C17H23NO5, CAS 2708287-92-5
Ethyl 8-(5-methoxypyridin-2-yl)-1,4-dioxaspiro[4.5]decane-8-carboxylate
CAS 2708287-92-5C17H23NO5