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Murcko scaffold

6-(Piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione scaffold

39 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
39
With full pages
5
Scaffold SMILES

O=c1cc(N2CCCCC2)[nH]c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-(Piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione page
Murcko scaffold O=c1cc(N2CCCCC2)[nH]c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

1,3-Dimethyl-6-piperidino-2,4(1H,3H)-pyrimidinedione chemical structure, C11H17N3O2, CAS 74151-86-3
1,3-Dimethyl-6-piperidino-2,4(1H,3H)-pyrimidinedione
CAS 74151-86-3C11H17N3O2
3-Ethyl-6-piperidin-1-yl-1H-pyrimidine-2,4-dione chemical structure, C11H17N3O2, CAS 863588-02-7
3-Ethyl-6-piperidin-1-yl-1H-pyrimidine-2,4-dione
CAS 863588-02-7C11H17N3O2
6-(4-Hydroxypiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C10H15N3O3, CAS 887444-40-8
6-(4-Hydroxypiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione
CAS 887444-40-8C10H15N3O3
3-Methyl-6-piperidin-1-yl-1H-pyrimidine-2,4-dione chemical structure, C10H15N3O2, CAS 218447-55-3
3-Methyl-6-piperidin-1-yl-1H-pyrimidine-2,4-dione
CAS 218447-55-3C10H15N3O2
1,3-Dimethyl-2,4-dioxo-6-(piperidin-1-yl)-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde chemical structure, C12H17N3O3, CAS 155544-40-4
1,3-Dimethyl-2,4-dioxo-6-(piperidin-1-yl)-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
CAS 155544-40-4C12H17N3O3
5-Amino-1,3-dimethyl-6-piperidin-1-ylpyrimidine-2,4-dione chemical structure, C11H18N4O2, CAS 61541-44-4
5-Amino-1,3-dimethyl-6-piperidin-1-ylpyrimidine-2,4-dione
CAS 61541-44-4C11H18N4O2
6-(Piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C9H13N3O2, CAS 73823-06-0
6-(Piperidin-1-yl)pyrimidine-2,4(1H,3H)-dione
CAS 73823-06-0C9H13N3O2
Ethyl 1-(1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-carboxylate chemical structure, C13H19N3O4, CAS 950275-78-2
Ethyl 1-(1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-carboxylate
CAS 950275-78-2C13H19N3O4
Ethyl 1-(1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-3-carboxylate chemical structure, C13H19N3O4, CAS 950275-83-9
Ethyl 1-(1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-3-carboxylate
CAS 950275-83-9C13H19N3O4
6-(4-Aminopiperidin-1-yl)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione chemical structure, C10H16N4O2, CAS 1338682-75-9
6-(4-Aminopiperidin-1-yl)-3-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS 1338682-75-9C10H16N4O2
6-(3-Aminopiperidino)-3-methyl-2,4(1H,3H)-pyrimidinedione chemical structure, C10H16N4O2, CAS 1338677-76-1
6-(3-Aminopiperidino)-3-methyl-2,4(1H,3H)-pyrimidinedione
CAS 1338677-76-1C10H16N4O2
1-(1-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-3-carboxylic acid chemical structure, C11H15N3O4, CAS 1338656-65-7
1-(1-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-3-carboxylic acid
CAS 1338656-65-7C11H15N3O4
1-(1-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-carboxylic acid chemical structure, C11H15N3O4, CAS 1338660-21-1
1-(1-Methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-carboxylic acid
CAS 1338660-21-1C11H15N3O4
(S)-6-(3-Aminopiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C10H16N4O2, CAS 2276316-91-5
(S)-6-(3-Aminopiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione
CAS 2276316-91-5C10H16N4O2
3-Methyl-6-(2-methylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C11H17N3O2, CAS 1235633-15-4
3-Methyl-6-(2-methylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione
CAS 1235633-15-4C11H17N3O2
3-Methyl-6-(4-methylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C11H17N3O2, CAS 1235327-57-7
3-Methyl-6-(4-methylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione
CAS 1235327-57-7C11H17N3O2
6-(2-Methylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C10H15N3O2, CAS 2098004-73-8
6-(2-Methylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione
CAS 2098004-73-8C10H15N3O2
6-(4-Methylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C10H15N3O2, CAS 2098043-81-1
6-(4-Methylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione
CAS 2098043-81-1C10H15N3O2
6-(3,5-Dimethylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C11H17N3O2, CAS 2097978-44-2
6-(3,5-Dimethylpiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione
CAS 2097978-44-2C11H17N3O2
6-(3,5-Dimethylpiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C12H19N3O2, CAS 2098043-87-7
6-(3,5-Dimethylpiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione
CAS 2098043-87-7C12H19N3O2
1-(2,6-Dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-carboxamide chemical structure, C10H14N4O3, CAS 2098043-91-3
1-(2,6-Dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)piperidine-4-carboxamide
CAS 2098043-91-3C10H14N4O3
6-(4-Hydroxypiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C9H13N3O3, CAS 2090953-60-7
6-(4-Hydroxypiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione
CAS 2090953-60-7C9H13N3O3
6-(4,4-Difluoropiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione chemical structure, C9H11F2N3O2, CAS 2098011-91-5
6-(4,4-Difluoropiperidin-1-yl)pyrimidine-2,4(1H,3H)-dione
CAS 2098011-91-5C9H11F2N3O2
6-(4,4-Difluoropiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C10H13F2N3O2, CAS 2097978-71-5
6-(4,4-Difluoropiperidin-1-yl)-3-methylpyrimidine-2,4(1H,3H)-dione
CAS 2097978-71-5C10H13F2N3O2