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Murcko scaffold

Ring system with 5 rings and 29 atoms

62 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
29
Chemicals
62
With full pages
4
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpiperidine-4-carboxylic acid chemical structure, C27H25NO4, CAS 215190-19-5
1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpiperidine-4-carboxylic acid
CAS 215190-19-5C27H25NO4
(3R,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpiperidine-3-carboxylic acid chemical structure, C27H25NO4, CAS 1014018-07-5
(3R,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpiperidine-3-carboxylic acid
CAS 1014018-07-5C27H25NO4
1-(9H-Fluoren-9-ylmethyl) 4-(4-bromophenyl)-1,4-piperidinedicarboxylate chemical structure, C27H24BrNO4, CAS 913542-81-1
1-(9H-Fluoren-9-ylmethyl) 4-(4-bromophenyl)-1,4-piperidinedicarboxylate
CAS 913542-81-1C27H24BrNO4
Fmoc-4-(4-chlorophenyl)-piperidine-4-carboxylic acid chemical structure, C27H24ClNO4, CAS 887129-04-6
Fmoc-4-(4-chlorophenyl)-piperidine-4-carboxylic acid
CAS 887129-04-6C27H24ClNO4
Fmoc-4-(4-fluorophenyl)-piperidine-4-carboxylic acid chemical structure, C27H24FNO4, CAS 1076197-06-2
Fmoc-4-(4-fluorophenyl)-piperidine-4-carboxylic acid
CAS 1076197-06-2C27H24FNO4
(9H-Fluoren-9-yl)methyl 4-(2-chlorophenyl)-4-hydroxypiperidine-1-carboxylate chemical structure, C26H24ClNO3, CAS 1198283-81-6
(9H-Fluoren-9-yl)methyl 4-(2-chlorophenyl)-4-hydroxypiperidine-1-carboxylate
CAS 1198283-81-6C26H24ClNO3
(9H-Fluoren-9-yl)methyl 4-(2-fluorophenyl)-4-hydroxypiperidine-1-carboxylate chemical structure, C26H24FNO3, CAS 1198287-02-3
(9H-Fluoren-9-yl)methyl 4-(2-fluorophenyl)-4-hydroxypiperidine-1-carboxylate
CAS 1198287-02-3C26H24FNO3
(9H-Fluoren-9-yl)methyl 4-(3-bromophenyl)-4-hydroxypiperidine-1-carboxylate chemical structure, C26H24BrNO3, CAS 1198286-19-9
(9H-Fluoren-9-yl)methyl 4-(3-bromophenyl)-4-hydroxypiperidine-1-carboxylate
CAS 1198286-19-9C26H24BrNO3
(9H-Fluoren-9-yl)methyl 4-(3-fluorophenyl)-4-hydroxypiperidine-1-carboxylate chemical structure, C26H24FNO3, CAS 1198287-03-4
(9H-Fluoren-9-yl)methyl 4-(3-fluorophenyl)-4-hydroxypiperidine-1-carboxylate
CAS 1198287-03-4C26H24FNO3
(9H-Fluoren-9-yl)methyl 4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate chemical structure, C26H24BrNO3, CAS 1198285-92-5
(9H-Fluoren-9-yl)methyl 4-(4-bromophenyl)-4-hydroxypiperidine-1-carboxylate
CAS 1198285-92-5C26H24BrNO3
(9H-Fluoren-9-yl)methyl 4-(4-chlorophenyl)-4-hydroxypiperidine-1-carboxylate chemical structure, C26H24ClNO3, CAS 1198287-11-4
(9H-Fluoren-9-yl)methyl 4-(4-chlorophenyl)-4-hydroxypiperidine-1-carboxylate
CAS 1198287-11-4C26H24ClNO3
(9H-Fluoren-9-yl)methyl 4-(4-fluorophenyl)-4-hydroxypiperidine-1-carboxylate chemical structure, C26H24FNO3, CAS 1198284-86-4
(9H-Fluoren-9-yl)methyl 4-(4-fluorophenyl)-4-hydroxypiperidine-1-carboxylate
CAS 1198284-86-4C26H24FNO3
(9H-Fluoren-9-yl)methyl 4-hydroxy-4-phenylpiperidine-1-carboxylate chemical structure, C26H25NO3, CAS 1198285-42-5
(9H-Fluoren-9-yl)methyl 4-hydroxy-4-phenylpiperidine-1-carboxylate
CAS 1198285-42-5C26H25NO3
(3S,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpiperidine-3-carboxylic acid chemical structure, C27H25NO4, CAS 2380869-42-9
(3S,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-phenylpiperidine-3-carboxylic acid
CAS 2380869-42-9C27H25NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(3-methylphenyl)piperidine-4-carboxylic acid chemical structure, C28H27NO4, CAS 2094196-23-1
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(3-methylphenyl)piperidine-4-carboxylic acid
CAS 2094196-23-1C28H27NO4
2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-4-yl)benzoic acid chemical structure, C27H25NO4, CAS 2125431-59-4
2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidin-4-yl)benzoic acid
CAS 2125431-59-4C27H25NO4
4-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)benzoic acid chemical structure, C27H25NO4, CAS 2137709-91-0
4-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)benzoic acid
CAS 2137709-91-0C27H25NO4
3-[1-(9H-Fluoren-9-ylmethoxycarbonyl)piperidin-4-yl]benzoic acid chemical structure, C27H25NO4, CAS 2375260-66-3
3-[1-(9H-Fluoren-9-ylmethoxycarbonyl)piperidin-4-yl]benzoic acid
CAS 2375260-66-3C27H25NO4
4-[3-({[(tert-Butoxy)carbonyl]amino}methyl)phenyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid chemical structure, C33H36N2O6, CAS 2137620-53-0
4-[3-({[(tert-Butoxy)carbonyl]amino}methyl)phenyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid
CAS 2137620-53-0C33H36N2O6
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(4-methylphenyl)piperidine-4-carboxylic acid chemical structure, C28H27NO4, CAS 2137896-34-3
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-(4-methylphenyl)piperidine-4-carboxylic acid
CAS 2137896-34-3C28H27NO4
5-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-2-hydroxybenzoic acid chemical structure, C27H25NO5, CAS 2171889-09-9
5-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl)-2-hydroxybenzoic acid
CAS 2171889-09-9C27H25NO5
2-{[4-(3-Bromophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl]oxy}acetic acid chemical structure, C28H26BrNO5, CAS 2309462-12-0
2-{[4-(3-Bromophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl]oxy}acetic acid
CAS 2309462-12-0C28H26BrNO5
2-{[4-(4-Bromophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl]oxy}acetic acid chemical structure, C28H26BrNO5, CAS 2309467-30-7
2-{[4-(4-Bromophenyl)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidin-4-yl]oxy}acetic acid
CAS 2309467-30-7C28H26BrNO5
4-[4-({[(tert-Butoxy)carbonyl]amino}methyl)phenyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid chemical structure, C33H36N2O6, CAS 2137620-50-7
4-[4-({[(tert-Butoxy)carbonyl]amino}methyl)phenyl]-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}piperidine-4-carboxylic acid
CAS 2137620-50-7C33H36N2O6