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Murcko scaffold

Ring system with 4 rings and 24 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
5
With full pages
1
Scaffold SMILES

O=c1ccc2cc(Nc3ccnc(N4CCCCC4)n3)ccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccc2cc(Nc3ccnc(N4CCCCC4)n3)ccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

BI-3802 chemical structure, C24H29ClN6O3, CAS 2166387-65-9
BI-3802
CAS 2166387-65-9C24H29ClN6O3
1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide chemical structure, C26H32ClN7O5, CAS 2166387-64-8
1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pyrimidin-2-yl)-N,N-dimethylpiperidine-4-carboxamide
CAS 2166387-64-8C26H32ClN7O5
2-{[6-({5-Chloro-2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl}amino)-1-methyl-2-oxo-1,2-dihydroquinolin-3-yl]oxy}acetic acid chemical structure, C23H26ClN5O4, CAS 2230407-57-3
2-{[6-({5-Chloro-2-[(3R,5S)-3,5-dimethylpiperidin-1-yl]pyrimidin-4-yl}amino)-1-methyl-2-oxo-1,2-dihydroquinolin-3-yl]oxy}acetic acid
CAS 2230407-57-3C23H26ClN5O4
BCL6 ligand-1 chemical structure, C24H27ClN6O6, CAS 2230407-20-0
BCL6 ligand-1
CAS 2230407-20-0C24H27ClN6O6
1-[4-({3-[2-(tert-Butoxy)-2-oxoethoxy]-1-methyl-2-oxo-1,2-dihydroquinolin-6-yl}amino)-5-chloropyrimidin-2-yl]piperidine-4-carboxylic acid chemical structure, C26H30ClN5O6, CAS 2751704-01-3
1-[4-({3-[2-(tert-Butoxy)-2-oxoethoxy]-1-methyl-2-oxo-1,2-dihydroquinolin-6-yl}amino)-5-chloropyrimidin-2-yl]piperidine-4-carboxylic acid
CAS 2751704-01-3C26H30ClN5O6