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Murcko scaffold

Ring system with 4 rings and 24 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
11
With full pages
2
Scaffold SMILES

O=c1cc(-c2ccccc2)nc(Nc2ncc3ccccc3n2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(-c2ccccc2)nc(Nc2ncc3ccccc3n2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-[(4-Methylquinazolin-2-yl)amino]-6-phenylpyrimidin-4-ol chemical structure, C19H15N5O, CAS 336176-55-7
2-[(4-Methylquinazolin-2-yl)amino]-6-phenylpyrimidin-4-ol
CAS 336176-55-7C19H15N5O
6-Phenyl-2-[(4,6,7-trimethylquinazolin-2-yl)amino]pyrimidin-4-ol chemical structure, C21H19N5O, CAS 336176-59-1
6-Phenyl-2-[(4,6,7-trimethylquinazolin-2-yl)amino]pyrimidin-4-ol
CAS 336176-59-1C21H19N5O
2-[(6-Methoxy-4-methylquinazolin-2-yl)amino]-6-phenylpyrimidin-4-ol chemical structure, C20H17N5O2, CAS 336176-63-7
2-[(6-Methoxy-4-methylquinazolin-2-yl)amino]-6-phenylpyrimidin-4-ol
CAS 336176-63-7C20H17N5O2
6-(4-Methoxyphenyl)-2-[(4,6,7-trimethyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone chemical structure, C22H21N5O2, CAS 876667-53-7
6-(4-Methoxyphenyl)-2-[(4,6,7-trimethyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone
CAS 876667-53-7C22H21N5O2
2-[(4,8-Dimethylquinazolin-2-yl)amino]-6-phenylpyrimidin-4-ol chemical structure, C20H17N5O, CAS 362000-29-1
2-[(4,8-Dimethylquinazolin-2-yl)amino]-6-phenylpyrimidin-4-ol
CAS 362000-29-1C20H17N5O
2-[(4,7-Dimethylquinazolin-2-yl)amino]-6-phenylpyrimidin-4-ol chemical structure, C20H17N5O, CAS 5819-53-4
2-[(4,7-Dimethylquinazolin-2-yl)amino]-6-phenylpyrimidin-4-ol
CAS 5819-53-4C20H17N5O
6-Phenyl-2-[(4,6,8-trimethyl-2-quinazolinyl)amino]-4-pyrimidinol chemical structure, C21H19N5O, CAS 336176-67-1
6-Phenyl-2-[(4,6,8-trimethyl-2-quinazolinyl)amino]-4-pyrimidinol
CAS 336176-67-1C21H19N5O
2-[(4,7-Dimethyl-2-quinazolinyl)amino]-6-(3-methoxyphenyl)-4(3H)-pyrimidinone chemical structure, C21H19N5O2, CAS 924874-32-8
2-[(4,7-Dimethyl-2-quinazolinyl)amino]-6-(3-methoxyphenyl)-4(3H)-pyrimidinone
CAS 924874-32-8C21H19N5O2
6-(4-Chlorophenyl)-2-[(8-methoxy-4-methyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone chemical structure, C20H16ClN5O2, CAS 921075-32-3
6-(4-Chlorophenyl)-2-[(8-methoxy-4-methyl-2-quinazolinyl)amino]-4(3H)-pyrimidinone
CAS 921075-32-3C20H16ClN5O2
2-[(4,7-Dimethyl-2-quinazolinyl)amino]-6-(2-methoxyphenyl)-4(3H)-pyrimidinone chemical structure, C21H19N5O2, CAS 921117-30-8
2-[(4,7-Dimethyl-2-quinazolinyl)amino]-6-(2-methoxyphenyl)-4(3H)-pyrimidinone
CAS 921117-30-8C21H19N5O2
2-[(4,6-Dimethyl-2-quinazolinyl)amino]-6-(3-methoxyphenyl)-4(3H)-pyrimidinone chemical structure, C21H19N5O2, CAS 921117-00-2
2-[(4,6-Dimethyl-2-quinazolinyl)amino]-6-(3-methoxyphenyl)-4(3H)-pyrimidinone
CAS 921117-00-2C21H19N5O2