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Murcko scaffold

Pyrazolo[1,5-a]pyrimidin-2-ol scaffold

31 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
31
With full pages
5
Scaffold SMILES

O=c1cc2ncccn2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrazolo[1,5-a]pyrimidin-2-ol page
Murcko scaffold O=c1cc2ncccn2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

Ethyl 2-hydroxy-5-methylpyrazolo(1,5-a)pyrimidine-6-carboxylate chemical structure, C10H11N3O3, CAS 57615-05-1
Ethyl 2-hydroxy-5-methylpyrazolo(1,5-a)pyrimidine-6-carboxylate
CAS 57615-05-1C10H11N3O3
5,7-Dimethylpyrazolo[1,5-a]pyrimidin-2-ol chemical structure, C8H9N3O, CAS 26911-66-0
5,7-Dimethylpyrazolo[1,5-a]pyrimidin-2-ol
CAS 26911-66-0C8H9N3O
5,7-Dimethyl-3-nitropyrazolo[1,5-a]pyrimidin-2(1H)-one chemical structure, C8H8N4O3, CAS 89977-75-3
5,7-Dimethyl-3-nitropyrazolo[1,5-a]pyrimidin-2(1H)-one
CAS 89977-75-3C8H8N4O3
3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2(1H)-one chemical structure, C8H8BrN3O, CAS 66383-54-8
3-Bromo-5,7-dimethylpyrazolo[1,5-a]pyrimidin-2(1H)-one
CAS 66383-54-8C8H8BrN3O
7-Methyl-2-oxo-1,2-dihydropyrazolo[1,5-A]pyrimidine-6-carboxylic acid chemical structure, C8H7N3O3, CAS 329207-48-9
7-Methyl-2-oxo-1,2-dihydropyrazolo[1,5-A]pyrimidine-6-carboxylic acid
CAS 329207-48-9C8H7N3O3
7-Methylpyrazolo[1,5-a]pyrimidin-2(1H)-one chemical structure, C7H7N3O, CAS 28491-57-8
7-Methylpyrazolo[1,5-a]pyrimidin-2(1H)-one
CAS 28491-57-8C7H7N3O
5-Methylpyrazolo[1,5-a]pyrimidin-2(1H)-one chemical structure, C7H7N3O, CAS 28491-56-7
5-Methylpyrazolo[1,5-a]pyrimidin-2(1H)-one
CAS 28491-56-7C7H7N3O
3-Bromo-5-methylpyrazolo[1,5-a]pyrimidin-2(1H)-one chemical structure, C7H6BrN3O, CAS 52130-64-0
3-Bromo-5-methylpyrazolo[1,5-a]pyrimidin-2(1H)-one
CAS 52130-64-0C7H6BrN3O
Pyrazolo[1,5-a]pyrimidin-2-ol chemical structure, C6H5N3O, CAS 39977-33-8
Pyrazolo[1,5-a]pyrimidin-2-ol
CAS 39977-33-8C6H5N3O
5-Methyl-2-oxo-1H-pyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C8H7N3O3, CAS 90004-33-4
5-Methyl-2-oxo-1H-pyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 90004-33-4C8H7N3O3
2-Hydroxy-6-isopropylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C10H11N3O3, CAS 1049873-38-2
2-Hydroxy-6-isopropylpyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 1049873-38-2C10H11N3O3
7-Ethyl-2-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C9H9N3O3, CAS 1049873-68-8
7-Ethyl-2-hydroxypyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 1049873-68-8C9H9N3O3
3-(2-Hydroxy-5,7-dimethylpyrazolo(1,5-a)pyrimidin-6-yl)propanoic acid chemical structure, C11H13N3O3, CAS 1144447-35-7
3-(2-Hydroxy-5,7-dimethylpyrazolo(1,5-a)pyrimidin-6-yl)propanoic acid
CAS 1144447-35-7C11H13N3O3
7-Aminopyrazolo[1,5-a]pyrimidin-2(1H)-one chemical structure, C6H6N4O, CAS 856587-85-4
7-Aminopyrazolo[1,5-a]pyrimidin-2(1H)-one
CAS 856587-85-4C6H6N4O
2-{5,7-Dimethyl-2-oxo-1H,2H-pyrazolo[1,5-a]pyrimidin-6-yl}acetic acid chemical structure, C10H11N3O3, CAS 1258639-52-9
2-{5,7-Dimethyl-2-oxo-1H,2H-pyrazolo[1,5-a]pyrimidin-6-yl}acetic acid
CAS 1258639-52-9C10H11N3O3
6-(Aminomethyl)-5,7-dimethyl-1H,2H-pyrazolo[1,5-a]pyrimidin-2-one dihydrochloride chemical structure, C9H14Cl2N4O, CAS 1306605-36-6
6-(Aminomethyl)-5,7-dimethyl-1H,2H-pyrazolo[1,5-a]pyrimidin-2-one dihydrochloride
CAS 1306605-36-6C9H14Cl2N4O
6-(Aminomethyl)-5,7-dimethyl-1H,2H-pyrazolo[1,5-a]pyrimidin-2-one chemical structure, C9H12N4O, CAS 1306831-05-9
6-(Aminomethyl)-5,7-dimethyl-1H,2H-pyrazolo[1,5-a]pyrimidin-2-one
CAS 1306831-05-9C9H12N4O
3-Chloro-7-ethylpyrazolo[1,5-a]pyrimidin-2(1H)-one chemical structure, C8H8ClN3O, CAS 63094-27-9
3-Chloro-7-ethylpyrazolo[1,5-a]pyrimidin-2(1H)-one
CAS 63094-27-9C8H8ClN3O
3-(3-Bromo-5,7-dimethyl-2-oxo-1,2-dihydropyrazolo[1,5-a]pyrimidin-6-yl)propanoic acid chemical structure, C11H12BrN3O3, CAS 1439441-60-7
3-(3-Bromo-5,7-dimethyl-2-oxo-1,2-dihydropyrazolo[1,5-a]pyrimidin-6-yl)propanoic acid
CAS 1439441-60-7C11H12BrN3O3
2-(tert-Butylsulfanyl)-N-({5,7-dimethyl-2-oxo-1H,2H-pyrazolo[1,5-a]pyrimidin-6-yl}methyl)acetamide chemical structure, C15H22N4O2S, CAS 1376378-67-4
2-(tert-Butylsulfanyl)-N-({5,7-dimethyl-2-oxo-1H,2H-pyrazolo[1,5-a]pyrimidin-6-yl}methyl)acetamide
CAS 1376378-67-4C15H22N4O2S
5,6-Dimethylpyrazolo[1,5-a]pyrimidin-2(1H)-one chemical structure, C8H9N3O, CAS 101259-15-8
5,6-Dimethylpyrazolo[1,5-a]pyrimidin-2(1H)-one
CAS 101259-15-8C8H9N3O
6-Bromopyrazolo[1,5-a]pyrimidin-2-ol chemical structure, C6H4BrN3O, CAS 1784859-24-0
6-Bromopyrazolo[1,5-a]pyrimidin-2-ol
CAS 1784859-24-0C6H4BrN3O
3,6-Dibromopyrazolo[1,5-a]pyrimidin-2-ol chemical structure, C6H3Br2N3O, CAS 1934742-81-0
3,6-Dibromopyrazolo[1,5-a]pyrimidin-2-ol
CAS 1934742-81-0C6H3Br2N3O
2-Oxo-1H,2H-pyrazolo[1,5-a]pyrimidine-7-carboxylic acid chemical structure, C7H5N3O3, CAS 2059934-93-7
2-Oxo-1H,2H-pyrazolo[1,5-a]pyrimidine-7-carboxylic acid
CAS 2059934-93-7C7H5N3O3