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Murcko scaffold

2,4-Diphenyl-1-butene scaffold

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
18
With full pages
5
Scaffold SMILES

C=C(CCc1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,4-Diphenyl-1-butene page
Murcko scaffold C=C(CCc1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

1,1'-(1,1-Dimethyl-3-methylene-1,3-propanediyl)bisbenzene chemical structure, C18H20, CAS 6362-80-7
1,1'-(1,1-Dimethyl-3-methylene-1,3-propanediyl)bisbenzene
CAS 6362-80-7C18H20
4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene chemical structure, C18H20O2, CAS 13464-24-9
4-Methyl-2,4-bis(4-hydroxyphenyl)pent-1-ene
CAS 13464-24-9C18H20O2
2,4-Diphenyl-1-butene chemical structure, C16H16, CAS 16606-47-6
2,4-Diphenyl-1-butene
CAS 16606-47-6C16H16
4-(p-Methoxybenzyl)-3-(p-methoxyphenyl)-2-hexene chemical structure, C21H26O2, CAS 74886-22-9
4-(p-Methoxybenzyl)-3-(p-methoxyphenyl)-2-hexene
CAS 74886-22-9C21H26O2
3,3 inverted exclamation mark-(4-Methylpent-1-ene-2,4-diyl)bis(prop-1-en-2-ylbenzene) chemical structure, C24H28, CAS 235428-39-4
3,3 inverted exclamation mark-(4-Methylpent-1-ene-2,4-diyl)bis(prop-1-en-2-ylbenzene)
CAS 235428-39-4C24H28
Benzene, 1,1'-(1-ethynyl-3-methylene-1,3-propanediyl)bis- chemical structure, C18H16, CAS 552843-63-7
Benzene, 1,1'-(1-ethynyl-3-methylene-1,3-propanediyl)bis-
CAS 552843-63-7C18H16
2,4-Bis(p-aminophenyl)-4-methyl-1-pentene chemical structure, C18H22N2, CAS 62741-12-2
2,4-Bis(p-aminophenyl)-4-methyl-1-pentene
CAS 62741-12-2C18H22N2
3,3'-(4-Methylpent-1-ene-2,4-diyl)diphenol chemical structure, C18H20O2, CAS 67833-41-4
3,3'-(4-Methylpent-1-ene-2,4-diyl)diphenol
CAS 67833-41-4C18H20O2
(2z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid chemical structure, C17H15ClO2, CAS 1180676-32-7
(2z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid
CAS 1180676-32-7C17H15ClO2
(E)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid chemical structure, C17H15ClO2, CAS 1180676-33-8
(E)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid
CAS 1180676-33-8C17H15ClO2
2-[1-(4-Methylphenyl)-4-nitro-3-phenylbutylidene]propanedinitrile chemical structure, C20H17N3O2, CAS 1245645-15-1
2-[1-(4-Methylphenyl)-4-nitro-3-phenylbutylidene]propanedinitrile
CAS 1245645-15-1C20H17N3O2
3-Ethyl-2,4-bis(p-methoxyphenyl)-1-hexene chemical structure, C22H28O2, CAS 131-88-4
3-Ethyl-2,4-bis(p-methoxyphenyl)-1-hexene
CAS 131-88-4C22H28O2
1,1'-(Hepta-3,4-diene-1,3-diyl)dibenzene chemical structure, C19H20, CAS 93269-66-0
1,1'-(Hepta-3,4-diene-1,3-diyl)dibenzene
CAS 93269-66-0C19H20
Trimethyl[(2-methyl-2,4-diphenylpent-4-en-1-yl)oxy]silane chemical structure, C21H28OSi, CAS 64960-61-8
Trimethyl[(2-methyl-2,4-diphenylpent-4-en-1-yl)oxy]silane
CAS 64960-61-8C21H28OSi
1,1'-(3,4-Dimethylhex-1-ene-2,4-diyl)dibenzene chemical structure, C20H24, CAS 63756-67-2
1,1'-(3,4-Dimethylhex-1-ene-2,4-diyl)dibenzene
CAS 63756-67-2C20H24
1,1'-(Hexa-1,5-diene-2,4-diyl)dibenzene chemical structure, C18H18, CAS 63779-63-5
1,1'-(Hexa-1,5-diene-2,4-diyl)dibenzene
CAS 63779-63-5C18H18
1,1'-(3,3-Dimethylbut-1-ene-2,4-diyl)dibenzene chemical structure, C18H20, CAS 830345-45-4
1,1'-(3,3-Dimethylbut-1-ene-2,4-diyl)dibenzene
CAS 830345-45-4C18H20
1,1'-(4-Methylpent-1-ene-2,4-diyl)bis(4-methoxybenzene) chemical structure, C20H24O2, CAS 61093-30-9
1,1'-(4-Methylpent-1-ene-2,4-diyl)bis(4-methoxybenzene)
CAS 61093-30-9C20H24O2