Murcko scaffold
3-Azabicyclo(3.1.1)heptane scaffold
338 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 7
- Chemicals
- 338
- With full pages
- 33
Scaffold SMILES
C1NCC2CC1C2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 338 chemicals
3-Azabicyclo(3.1.1)heptane
CAS 286-35-1C6H11N
![1,5-Dimethyl-3-azabicyclo[3.1.1]heptane chemical structure, C8H15N, CAS 762205-29-8](/s/WACADVNFKQVOQM-UHFFFAOYSA-N.svg)
1,5-Dimethyl-3-azabicyclo[3.1.1]heptane
CAS 762205-29-8C8H15N
![3-Azabicyclo[3.1.1]heptan-1-amine dihydrochloride chemical structure, C6H14Cl2N2, CAS 220593-83-9](/s/PRUAOXGNFKCGNL-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.1]heptan-1-amine dihydrochloride
CAS 220593-83-9C6H14Cl2N2
![3-Azabicyclo[3.1.1]heptan-1-amine chemical structure, C6H12N2, CAS 175867-89-7](/s/SUDNTMIZLPOVKE-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.1]heptan-1-amine
CAS 175867-89-7C6H12N2
3-((tert-Butoxy)carbonyl)-3-azabicyclo(3.1.1)heptane-1-carboxylic acid
CAS 1000931-22-5C12H19NO4
![{3-Azabicyclo[3.1.1]heptan-1-yl}methanol chemical structure, C7H13NO, CAS 1172693-01-4](/s/LGEAVVCHHFVNQZ-UHFFFAOYSA-N.svg)
{3-Azabicyclo[3.1.1]heptan-1-yl}methanol
CAS 1172693-01-4C7H13NO
![tert-Butyl 1-(hydroxymethyl)-3-azabicyclo[3.1.1]heptane-3-carboxylate chemical structure, C12H21NO3, CAS 1087784-78-8](/s/POCJKYARJWWJGO-UHFFFAOYSA-N.svg)
tert-Butyl 1-(hydroxymethyl)-3-azabicyclo[3.1.1]heptane-3-carboxylate
CAS 1087784-78-8C12H21NO3
![3-Azabicyclo[3.1.1]heptan-1-ylmethanol hydrochloride chemical structure, C7H14ClNO, CAS 1172575-76-6](/s/DUEOSOPPSMJXBC-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.1]heptan-1-ylmethanol hydrochloride
CAS 1172575-76-6C7H14ClNO
tert-Butyl N-(3-azabicyclo(3.1.1)heptan-1-yl)carbamate
CAS 175868-01-6C11H20N2O2
![6,6-Dimethoxy-3-azabicyclo[3.1.1]heptane chemical structure, C8H15NO2, CAS 1240526-70-8](/s/RJFNHIDLZOEEQT-UHFFFAOYSA-N.svg)
6,6-Dimethoxy-3-azabicyclo[3.1.1]heptane
CAS 1240526-70-8C8H15NO2
![3-Azabicyclo[3.1.1]heptan-6-ol chemical structure, C6H11NO, CAS 1389441-76-2](/s/BOTJOIYABJNMEW-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.1]heptan-6-ol
CAS 1389441-76-2C6H11NO
![3-Azabicyclo[3.1.1]heptane-6-carboxylic acid hydrochloride chemical structure, C7H12ClNO2, CAS 1240525-76-1](/s/DTSINJOVEHJXAR-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.1]heptane-6-carboxylic acid hydrochloride
CAS 1240525-76-1C7H12ClNO2
![3-Azabicyclo[3.1.1]heptane-6-carboxylic acid chemical structure, C7H11NO2, CAS 1240562-06-4](/s/CHNUPIXQOUGTML-UHFFFAOYSA-N.svg)
3-Azabicyclo[3.1.1]heptane-6-carboxylic acid
CAS 1240562-06-4C7H11NO2
![6-(Trifluoromethyl)-3-azabicyclo[3.1.1]heptan-6-ol chemical structure, C7H10F3NO, CAS 1240525-82-9](/s/KCXJTFQFEKXYHG-UHFFFAOYSA-N.svg)
6-(Trifluoromethyl)-3-azabicyclo[3.1.1]heptan-6-ol
CAS 1240525-82-9C7H10F3NO
![3-Methyl-3-azabicyclo[3.1.1]heptan-6-amine chemical structure, C7H14N2, CAS 1240526-72-0](/s/VBRGCOXFBWLERV-UHFFFAOYSA-N.svg)
3-Methyl-3-azabicyclo[3.1.1]heptan-6-amine
CAS 1240526-72-0C7H14N2
![3-Ethyl-3-azabicyclo[3.1.1]heptan-6-amine chemical structure, C8H16N2, CAS 1240527-81-4](/s/XXPXFCKDCSUTOC-UHFFFAOYSA-N.svg)
3-Ethyl-3-azabicyclo[3.1.1]heptan-6-amine
CAS 1240527-81-4C8H16N2
![3-Propyl-3-azabicyclo[3.1.1]heptan-6-amine chemical structure, C9H18N2, CAS 1240527-53-0](/s/ZQMOVDOMWQBNPG-UHFFFAOYSA-N.svg)
3-Propyl-3-azabicyclo[3.1.1]heptan-6-amine
CAS 1240527-53-0C9H18N2
![3-(Propan-2-yl)-3-azabicyclo[3.1.1]heptan-6-amine chemical structure, C9H18N2, CAS 1240529-32-1](/s/OGAACZCNAIYNIN-UHFFFAOYSA-N.svg)
3-(Propan-2-yl)-3-azabicyclo[3.1.1]heptan-6-amine
CAS 1240529-32-1C9H18N2
![3-Butyl-3-azabicyclo[3.1.1]heptan-6-amine chemical structure, C10H20N2, CAS 1240527-04-1](/s/JHMXTLXVCHIQMC-UHFFFAOYSA-N.svg)
3-Butyl-3-azabicyclo[3.1.1]heptan-6-amine
CAS 1240527-04-1C10H20N2
![3-(2-Methylpropyl)-3-azabicyclo[3.1.1]heptan-6-amine chemical structure, C10H20N2, CAS 1240526-28-6](/s/RKQCXMXBSOJGHN-UHFFFAOYSA-N.svg)
3-(2-Methylpropyl)-3-azabicyclo[3.1.1]heptan-6-amine
CAS 1240526-28-6C10H20N2
![3-tert-Butyl-3-azabicyclo[3.1.1]heptan-6-amine chemical structure, C10H20N2, CAS 1240526-90-2](/s/KOBBIZUHSYCCIG-UHFFFAOYSA-N.svg)
3-tert-Butyl-3-azabicyclo[3.1.1]heptan-6-amine
CAS 1240526-90-2C10H20N2
![6,6-Difluoro-3-azabicyclo[3.1.1]heptane chemical structure, C6H9F2N, CAS 1251923-21-3](/s/OPKGZZULJOUJEV-UHFFFAOYSA-N.svg)
6,6-Difluoro-3-azabicyclo[3.1.1]heptane
CAS 1251923-21-3C6H9F2N
![(1R,5S,6R)-3-Azabicyclo[3.1.1]heptane-6-carboxylic acid chemical structure, C7H11NO2, CAS 1335234-04-2](/s/CHNUPIXQOUGTML-XEAPYIEGSA-N.svg)
(1R,5S,6R)-3-Azabicyclo[3.1.1]heptane-6-carboxylic acid
CAS 1335234-04-2C7H11NO2
![(1R,5S,6r)-3-Azabicyclo[3.1.1]heptan-6-ol chemical structure, C6H11NO, CAS 2355191-37-4](/s/BOTJOIYABJNMEW-XEAPYIEGSA-N.svg)
(1R,5S,6r)-3-Azabicyclo[3.1.1]heptan-6-ol
CAS 2355191-37-4C6H11NO
- (1R,5S,6s)-6-(Trifluoromethyl)-3-azabicyclo[3.1.1]heptan-6-ol2749841-69-6C7H10F3NO
- (meso-1R,5S,6R)-tert-butyl 6-hydroxy-3-azabicyclo[3.1.1]heptane-3-carboxylate1357353-36-6C11H19NO3
- tert-Butyl (1R,5S,6R)-6-amino-3-azabicyclo[3.1.1]heptane-3-carboxylate1250997-08-0C11H20N2O2
- 1 suppliers3-Azabicyclo(3.1.1)heptane hydrochloride1427380-44-6C6H12ClN
- tert-Butyl 6-amino-3-azabicyclo[3.1.1]heptane-3-carboxylate1427359-44-1C11H20N2O2
- 6-(Boc-amino)-3-azabicyclo[3.1.1]heptane1363382-46-0C11H20N2O2
- Methyl 3-azabicyclo[3.1.1]heptane-6-carboxylate, hydrochloride1389264-36-1C8H14ClNO2
- Methyl 3-azabicyclo[3.1.1]heptane-6-carboxylate1363381-51-4C8H13NO2
- tert-Butyl 6-hydroxy-3-azabicyclo[3.1.1]heptane-3-carboxylate1523617-90-4C11H19NO3
- tert-Butyl 6-(aminomethyl)-3-azabicyclo[3.1.1]heptane-3-carboxylate1251013-49-6C12H22N2O2
- 3-Boc-3-azabicyclo[3.1.1]heptane-6-carboxylic acid1427460-12-5C12H19NO4
- 3-Azabicyclo(3.1.1)heptan-6-ol, hydrochloride (1:1)1389264-28-1C6H12ClNO
- 6-Hydroxymethyl-3-aza-bicyclo[3.1.1]heptane1389264-30-5C7H13NO
- tert-Butyl 6-(hydroxymethyl)-3-azabicyclo[3.1.1]heptane-3-carboxylate1363383-36-1C12H21NO3
- 3-Boc-3-azabicyclo[3.1.1]heptane-6-carboxamide1392803-91-6C12H20N2O3
- 6-(Boc-aminomethyl)-3-azabicyclo[3.1.1]heptane1363382-87-9C12H22N2O2
- Methyl 3-Boc-3-azabicyclo[3.1.1]heptane-6-carboxylate1363380-75-9C13H21NO4
- 3-Azabicyclo[3.1.1]heptane-1-carboxylic acid hydrochloride1628783-92-5C7H12ClNO2
- 3-Azabicyclo[3.1.1]heptane-1-carboxylic acid1628897-76-6C7H11NO2
- tert-Butyl 6-cyano-3-azabicyclo[3.1.1]heptane-3-carboxylate1823484-78-1C12H18N2O2
- tert-Butyl N-(3-azabicyclo(3.1.1)heptan-6-yl)carbamate oxalate1803607-90-0C13H22N2O6
- 6,6-Dimethyl-3-azabicyclo[3.1.1]heptane1503972-53-9C8H15N
- 2-(3-Azabicyclo[3.1.1]heptan-3-yl)ethan-1-amine1785544-98-0C8H16N2
- 3-Azabicyclo[3.1.1]heptane-2-carboxylic acid1779441-18-7C7H11NO2
Related scaffolds
Same ring framework with different atoms or bond orders
