Murcko scaffold
Lerisetron scaffold
58 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 22
- Chemicals
- 58
- With full pages
- 1
Scaffold SMILES
c1ccc(Cn2c(N3CCNCC3)nc3ccccc32)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 58 chemicals
Lerisetron
CAS 143257-98-1C18H20N4
1H-Benzimidazole, 5,6-dimethyl-1-(phenylmethyl)-2-(1-piperazinyl)-
CAS 184832-28-8C20H24N4
![tert-Butyl 4-(1-(4-methoxybenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C24H30N4O3, CAS 497870-06-1](/s/RAKFNPADIWLESN-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(4-methoxybenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 497870-06-1C24H30N4O3
1-(4-Fluoro-benzyl)-2-piperazin-1-yl-1H-benzoimidazole
CAS 142617-98-9C18H19FN4
![4-(1-Benzyl-1H-benzo[d]imidazol-2-yl)-N-(2-methoxyethyl)piperazine-1-carboxamide chemical structure, C22H27N5O2, CAS 1115390-86-7](/s/APZVPHOHNQZCGI-UHFFFAOYSA-N.svg)
4-(1-Benzyl-1H-benzo[d]imidazol-2-yl)-N-(2-methoxyethyl)piperazine-1-carboxamide
CAS 1115390-86-7C22H27N5O2
1-(4-Fluoro-benzyl)-2-piperazin-1-YL-1H-benzoimidazole dihydrochloride
CAS 1187930-00-2C18H21Cl2FN4
![1-(3-Fluorobenzyl)-2-(piperazin-1-yl)-1H-benzo[d]imidazole chemical structure, C18H19FN4, CAS 1420816-51-8](/s/NRRJXUKXLSFEBV-UHFFFAOYSA-N.svg)
1-(3-Fluorobenzyl)-2-(piperazin-1-yl)-1H-benzo[d]imidazole
CAS 1420816-51-8C18H19FN4
![tert-Butyl 4-(1-(2,6-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H26Cl2N4O2, CAS 1420874-66-3](/s/MMOVDRABRGYQJZ-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(2,6-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420874-66-3C23H26Cl2N4O2
![tert-Butyl 4-(1-(2-chloro-6-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H26ClFN4O2, CAS 1420999-80-9](/s/HJMMQIFQMKPPQD-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(2-chloro-6-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420999-80-9C23H26ClFN4O2
![tert-Butyl 4-(1-(3,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H26Cl2N4O2, CAS 1420958-30-0](/s/UAWBMOUHKZIAAP-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(3,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420958-30-0C23H26Cl2N4O2
![tert-Butyl 4-(1-(3-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H27ClN4O2, CAS 1421002-10-9](/s/QBJREQJZGGNWBU-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(3-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1421002-10-9C23H27ClN4O2
![tert-Butyl 4-(1-(2,5-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H26Cl2N4O2, CAS 1420882-99-0](/s/ZKTIAZKXHNOFND-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(2,5-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420882-99-0C23H26Cl2N4O2
![tert-Butyl 4-(1-(3-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H27FN4O2, CAS 1420798-34-0](/s/HNDHALKZLMUELN-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(3-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420798-34-0C23H27FN4O2
![tert-Butyl 4-(1-(4-bromobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H27BrN4O2, CAS 1421000-64-7](/s/ZHZVASMHLCTOQK-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(4-bromobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1421000-64-7C23H27BrN4O2
![tert-Butyl 4-(1-(4-cyanobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C24H27N5O2, CAS 1420826-85-2](/s/UTVXQHUVJWTDDW-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(4-cyanobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420826-85-2C24H27N5O2
![tert-Butyl 4-(1-(4-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H27ClN4O2, CAS 1421000-27-2](/s/WVORVGQHLJCXJA-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(4-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1421000-27-2C23H27ClN4O2
![tert-Butyl 4-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H26Cl2N4O2, CAS 1420886-94-7](/s/YFMPFOKCDPTSRB-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420886-94-7C23H26Cl2N4O2
![tert-Butyl 4-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H27FN4O2, CAS 1420885-56-8](/s/OLGPDYCHOJEYDG-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420885-56-8C23H27FN4O2
![tert-Butyl 4-(1-(2-cyanobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C24H27N5O2, CAS 1420959-64-3](/s/OPTBSASASSKRPA-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(2-cyanobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420959-64-3C24H27N5O2
![tert-Butyl 4-(1-(2-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H27ClN4O2, CAS 1420809-79-5](/s/UCIWPWINFNQYQR-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(2-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420809-79-5C23H27ClN4O2
![tert-Butyl 4-(1-(2-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C23H27FN4O2, CAS 1421002-46-1](/s/YQVGXXWXNQJGOF-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(2-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1421002-46-1C23H27FN4O2
![tert-Butyl 4-(1-(4-methylbenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C24H30N4O2, CAS 1420827-10-6](/s/AWFWAXHXBCKTOQ-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(4-methylbenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420827-10-6C24H30N4O2
![tert-Butyl 4-(1-(2-methylbenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate chemical structure, C24H30N4O2, CAS 1420841-46-8](/s/LJWINXJVZQMSAL-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(2-methylbenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate
CAS 1420841-46-8C24H30N4O2
![tert-Butyl 4-(1-(2,6-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate chemical structure, C24H28Cl2N4O2, CAS 1420975-86-5](/s/AMXMFCJSPBZAED-UHFFFAOYSA-N.svg)
tert-Butyl 4-(1-(2,6-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate
CAS 1420975-86-5C24H28Cl2N4O2
- tert-Butyl 4-(1-(2-chloro-6-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420863-27-9C24H28ClFN4O2
- tert-Butyl 4-(1-(3,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1421000-57-8C24H28Cl2N4O2
- tert-Butyl 4-(1-(3-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420875-29-1C24H29ClN4O2
- tert-Butyl 4-(1-(2,5-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420986-68-0C24H28Cl2N4O2
- tert-Butyl 4-(1-(3-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420974-76-0C24H29FN4O2
- tert-Butyl 4-(1-(4-bromobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420888-95-4C24H29BrN4O2
- tert-Butyl 2-methyl-4-(1-(4-methylbenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate1420861-75-1C25H32N4O2
- tert-Butyl 4-(1-(4-cyanobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420890-05-6C25H29N5O2
- tert-Butyl 4-(1-(4-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1421002-18-7C24H29ClN4O2
- tert-Butyl 4-(1-(2,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420882-89-8C24H28Cl2N4O2
- tert-Butyl 4-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420886-15-2C24H29FN4O2
- tert-Butyl 2-methyl-4-(1-(2-methylbenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate1420828-34-7C25H32N4O2
- tert-Butyl 4-(1-(2-cyanobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420845-07-3C25H29N5O2
- tert-Butyl 4-(1-(2-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420884-70-3C24H29ClN4O2
- tert-Butyl 4-(1-(2-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-2-methylpiperazine-1-carboxylate1420865-14-0C24H29FN4O2
- tert-Butyl 4-(1-(2,6-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)-3-methylpiperazine-1-carboxylate1420825-39-3C24H28Cl2N4O2
- tert-Butyl 4-(1-(2-chloro-6-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-3-methylpiperazine-1-carboxylate1420968-30-4C24H28ClFN4O2
- tert-Butyl 4-(1-(3,4-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)-3-methylpiperazine-1-carboxylate1420999-56-9C24H28Cl2N4O2
- tert-Butyl 4-(1-(3-chlorobenzyl)-1H-benzo[d]imidazol-2-yl)-3-methylpiperazine-1-carboxylate1420864-67-0C24H29ClN4O2
- tert-Butyl 4-(1-(2,5-dichlorobenzyl)-1H-benzo[d]imidazol-2-yl)-3-methylpiperazine-1-carboxylate1420797-53-0C24H28Cl2N4O2
- tert-Butyl 4-(1-(3-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-3-methylpiperazine-1-carboxylate1421002-23-4C24H29FN4O2
- tert-Butyl 4-(1-(4-bromobenzyl)-1H-benzo[d]imidazol-2-yl)-3-methylpiperazine-1-carboxylate1420865-75-3C24H29BrN4O2
- tert-Butyl 3-methyl-4-(1-(4-methylbenzyl)-1H-benzo[d]imidazol-2-yl)piperazine-1-carboxylate1420884-89-4C25H32N4O2
- tert-Butyl 4-(1-(4-cyanobenzyl)-1H-benzo[d]imidazol-2-yl)-3-methylpiperazine-1-carboxylate1420799-08-1C25H29N5O2
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Oc2c(-c3ccccc3)sc3ccccc23)cc11 chemical
O=C(c1ccccc1)c1c(-c2ccccc2)oc2ccccc121 chemical
c1ccc(-c2nc3ccccn3c2CN2CCOCC2)cc11 chemical
c1ccc(Cn2c(-c3ccccc3)nc3ccccc32)cc11 chemical![Scaffold O=c1[nH]c(=O)c2c(nc(N3CCNCC3)n2Cc2ccccc2)[nH]1](/scaffold/QVRTZFVIRFITBG-UHFFFAOYSA-N/structure.svg)
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O=S1C(c2ccccc2)=C(Oc2ccccc2)c2ccccc211 chemical
O=C(c1c(-c2ccccc2)oc2ccccc12)N1CCOCC11 chemical
c1ccc(Nc2c(-c3ccccc3)nc3cnccn23)cc11 chemical