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Murcko scaffold

Ring system with 4 rings and 25 atoms

151 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 25
Chemicals: 151
With full pages: 50

Scaffold SMILES

N=c1[nH]c2nc3ccccn3c(=O)c2cc1S(=O)(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold N=c1[nH]c2nc3ccccn3c(=O)c2cc1S(=O)(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 151 chemicals

2-Azanylidene-1-methyl-3-(phenylsulfonyl)dipyrido[1,2-e:4'',3''-f]pyrimidin-5-one chemical structure, C18H14N4O3S, CAS 797772-28-2

2-Azanylidene-1-methyl-3-(phenylsulfonyl)dipyrido[1,2-e:4'',3''-f]pyrimidin-5-one

CAS 797772-28-2C₁₈H₁₄N₄O₃S

2-Imino-1-methyl-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one chemical structure, C19H16N4O3S, CAS 371234-82-1

2-Imino-1-methyl-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one

CAS 371234-82-1C₁₉H₁₆N₄O₃S

1-Ethyl-3-((4-fluorophenyl)sulfonyl)-2-imino-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one chemical structure, C19H15FN4O3S, CAS 848727-50-4

1-Ethyl-3-((4-fluorophenyl)sulfonyl)-2-imino-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one

CAS 848727-50-4C₁₉H₁₅FN₄O₃S

3-[(4-Chlorophenyl)sulfonyl]-2-imino-1-methyl-1,6-dihydropyridino[1,2-a]pyridi no[2,3-d]pyrimidin-5-one chemical structure, C18H13ClN4O3S, CAS 848734-61-2

3-[(4-Chlorophenyl)sulfonyl]-2-imino-1-methyl-1,6-dihydropyridino[1,2-a]pyridi no[2,3-d]pyrimidin-5-one

CAS 848734-61-2C₁₈H₁₃ClN₄O₃S

3-((4-Fluorophenyl)sulfonyl)-2-imino-1-methyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one chemical structure, C18H13FN4O3S, CAS 877809-40-0

3-((4-Fluorophenyl)sulfonyl)-2-imino-1-methyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one

CAS 877809-40-0C₁₈H₁₃FN₄O₃S

1-Allyl-2-imino-10-methyl-3-(phenylsulfonyl)-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one chemical structure, C21H18N4O3S, CAS 371203-70-2

1-Allyl-2-imino-10-methyl-3-(phenylsulfonyl)-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one

CAS 371203-70-2C₂₁H₁₈N₄O₃S

2-Imino-10-methyl-3-((4-methylphenyl)sulfonyl)-1-propyl-1,2-dihydro-5H-dipyrido(1,2-A:2,3-D)pyrimidin-5-one chemical structure, C22H22N4O3S, CAS 606958-77-4

2-Imino-10-methyl-3-((4-methylphenyl)sulfonyl)-1-propyl-1,2-dihydro-5H-dipyrido(1,2-A:2,3-D)pyrimidin-5-one

CAS 606958-77-4C₂₂H₂₂N₄O₃S

1-Ethyl-2-imino-3-(phenylsulfonyl)-1,2-dihydro-5H-dipyrido(1,2-A:2,3-D)pyrimidin-5-one chemical structure, C19H16N4O3S, CAS 500144-41-2

1-Ethyl-2-imino-3-(phenylsulfonyl)-1,2-dihydro-5H-dipyrido(1,2-A:2,3-D)pyrimidin-5-one

CAS 500144-41-2C₁₉H₁₆N₄O₃S

3-[(4-Chlorophenyl)sulfonyl]-1-ethyl-2-imino-1,2-dihydro-5H-dipyrido[1,2-A:2,3-D]pyrimidin-5-one chemical structure, C19H15ClN4O3S, CAS 578005-66-0

3-[(4-Chlorophenyl)sulfonyl]-1-ethyl-2-imino-1,2-dihydro-5H-dipyrido[1,2-A:2,3-D]pyrimidin-5-one

CAS 578005-66-0C₁₉H₁₅ClN₄O₃S

1-Ethyl-2-imino-3-((4-methylphenyl)sulfonyl)-1,2-dihydro-5H-dipyrido(1,2-A:2,3-D)pyrimidin-5-one chemical structure, C20H18N4O3S, CAS 606955-21-9

1-Ethyl-2-imino-3-((4-methylphenyl)sulfonyl)-1,2-dihydro-5H-dipyrido(1,2-A:2,3-D)pyrimidin-5-one

CAS 606955-21-9C₂₀H₁₈N₄O₃S

1-Allyl-2-imino-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-A:2,3-D]pyrimidin-5-one chemical structure, C21H18N4O3S, CAS 606957-89-5

1-Allyl-2-imino-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-A:2,3-D]pyrimidin-5-one

CAS 606957-89-5C₂₁H₁₈N₄O₃S

1-Allyl-3-((4-chlorophenyl)sulfonyl)-2-imino-1,2-dihydro-5H-dipyrido(1,2-A:2,3-D)pyrimidin-5-one chemical structure, C20H15ClN4O3S, CAS 606958-72-9

1-Allyl-3-((4-chlorophenyl)sulfonyl)-2-imino-1,2-dihydro-5H-dipyrido(1,2-A:2,3-D)pyrimidin-5-one

CAS 606958-72-9C₂₀H₁₅ClN₄O₃S

2-Imino-10-methyl-3-(phenylsulfonyl)-1-propyl-1,2-dihydro-5H-dipyrido[1,2-A:2,3-D]pyrimidin-5-one chemical structure, C21H20N4O3S, CAS 606957-68-0

2-Imino-10-methyl-3-(phenylsulfonyl)-1-propyl-1,2-dihydro-5H-dipyrido[1,2-A:2,3-D]pyrimidin-5-one

CAS 606957-68-0C₂₁H₂₀N₄O₃S

3-[(4-Chlorophenyl)sulfonyl]-1-ethyl-2-imino-10-methyl-1,2-dihydro-5H-dipyrido[1,2-a:2',3'-d]pyrimidin-5-one chemical structure, C20H17ClN4O3S, CAS 579439-64-8

3-[(4-Chlorophenyl)sulfonyl]-1-ethyl-2-imino-10-methyl-1,2-dihydro-5H-dipyrido[1,2-a:2',3'-d]pyrimidin-5-one

CAS 579439-64-8C₂₀H₁₇ClN₄O₃S

1-Allyl-2-imino-8-methyl-3-(toluene-4-sulfonyl)-1,2-dihydro-1,9,10a-triaza-anthr chemical structure, C22H20N4O3S, CAS 371142-23-3

1-Allyl-2-imino-8-methyl-3-(toluene-4-sulfonyl)-1,2-dihydro-1,9,10a-triaza-anthr

CAS 371142-23-3C₂₂H₂₀N₄O₃S

1-Ethyl-2-imino-10-methyl-3-(phenylsulfonyl)-1,2-dihydro-5H-dipyrido[1,2-A:2,3-D]pyrimidin-5-one chemical structure, C20H18N4O3S, CAS 371117-01-0

1-Ethyl-2-imino-10-methyl-3-(phenylsulfonyl)-1,2-dihydro-5H-dipyrido[1,2-A:2,3-D]pyrimidin-5-one

CAS 371117-01-0C₂₀H₁₈N₄O₃S

1-Ethyl-2-imino-8-methyl-3-(toluene-4-sulfonyl)-1,2-dihydro-1,9,10a-triaza-anthr chemical structure, C21H20N4O3S, CAS 606955-64-0

1-Ethyl-2-imino-8-methyl-3-(toluene-4-sulfonyl)-1,2-dihydro-1,9,10a-triaza-anthr

CAS 606955-64-0C₂₁H₂₀N₄O₃S

1-Allyl-3-[(4-chlorophenyl)sulfonyl]-2-imino-10-methyl-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one chemical structure, C21H17ClN4O3S, CAS 578762-56-8

1-Allyl-3-[(4-chlorophenyl)sulfonyl]-2-imino-10-methyl-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one

CAS 578762-56-8C₂₁H₁₇ClN₄O₃S

1-(2-Hydroxyethyl)-2-imino-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one chemical structure, C20H18N4O4S, CAS 371141-33-2

1-(2-Hydroxyethyl)-2-imino-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one

CAS 371141-33-2C₂₀H₁₈N₄O₄S

1-(2-Hydroxyethyl)-2-imino-10-methyl-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one chemical structure, C21H20N4O4S, CAS 370870-32-9

1-(2-Hydroxyethyl)-2-imino-10-methyl-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one

CAS 370870-32-9C₂₁H₂₀N₄O₄S

2-Imino-3-[(4-methylphenyl)sulfonyl]-1-propyl-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one chemical structure, C21H20N4O3S, CAS 606958-44-5

2-Imino-3-[(4-methylphenyl)sulfonyl]-1-propyl-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one

CAS 606958-44-5C₂₁H₂₀N₄O₃S

2-Imino-1,10-dimethyl-3-(phenylsulfonyl)-1,6-dihydropyridino[2,3-d]pyridino[1, 2-a]pyrimidin-5-one chemical structure, C19H16N4O3S, CAS 636991-04-3

2-Imino-1,10-dimethyl-3-(phenylsulfonyl)-1,6-dihydropyridino[2,3-d]pyridino[1, 2-a]pyrimidin-5-one

CAS 636991-04-3C₁₉H₁₆N₄O₃S

1-Allyl-2-imino-8-methyl-3-(phenylsulfonyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one chemical structure, C21H18N4O3S, CAS 606957-48-6

1-Allyl-2-imino-8-methyl-3-(phenylsulfonyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one

CAS 606957-48-6C₂₁H₁₈N₄O₃S

1-Ethyl-2-imino-8-methyl-3-(phenylsulfonyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one chemical structure, C20H18N4O3S, CAS 606954-81-8

1-Ethyl-2-imino-8-methyl-3-(phenylsulfonyl)-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one

CAS 606954-81-8C₂₀H₁₈N₄O₃S