Murcko scaffold
7-[(Oxan-2-yl)oxy]-2H-1-benzopyran-2-one scaffold
141 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 141
- With full pages
- 29
Scaffold SMILES
O=c1ccc2ccc(OC3CCCCO3)cc2o1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 97 to 141 of 141 chemicals
![[(2R,3S,4R,5R,6R)-5-Acetamido-3,4-dihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl hydrogen sulfate chemical structure, C18H21NO11S, CAS 154639-35-7](/s/FEMWMNCEGXUBRL-FGTAOJJYSA-N.svg)
[(2R,3S,4R,5R,6R)-5-Acetamido-3,4-dihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl hydrogen sulfate
CAS 154639-35-7C18H21NO11S
4-Methylumbelliferyl 6-thio-palmitate-beta-D-glucopyranoside
CAS 229644-17-1C32H48O8S
![Methyl (2S,4S,5R,6R)-5-acetamido-4-acetyloxy-2-[2-oxo-4-(trifluoromethyl)chromen-7-yl]oxy-6-[(2S)-1,2,3-triacetyloxypropyl]oxane-2-carboxylate chemical structure, C30H32F3NO15, CAS 195210-09-4](/s/OSBBVRZZLWPPFC-HMIXGCIYSA-N.svg)
Methyl (2S,4S,5R,6R)-5-acetamido-4-acetyloxy-2-[2-oxo-4-(trifluoromethyl)chromen-7-yl]oxy-6-[(2S)-1,2,3-triacetyloxypropyl]oxane-2-carboxylate
CAS 195210-09-4C30H32F3NO15
4-Trifluoromethylumbelliferyl b-D-glucuronide potassium salt
CAS 143547-78-8C16H12F3KO9
![N-[7-(3,4-Dihydroxy-5-methoxy-6,6-dimethyloxan-2-yl)oxy-8-methyl-2-oxochromen-3-yl]acetamide chemical structure, C20H25NO8](/s/KJAWXHNSLFJNTM-UHFFFAOYSA-N.svg)
N-[7-(3,4-Dihydroxy-5-methoxy-6,6-dimethyloxan-2-yl)oxy-8-methyl-2-oxochromen-3-yl]acetamide
C20H25NO8
4-Methylumbelliferyl-beta-D-glucosaminide Hydrochloride
CAS 77160-51-1C16H20ClNO7
6-Chloro-4-methylumbelliferyl beta-D-glucuronide
CAS 947175-17-9C16H15ClO9
4-Methylumbelliferyl alpha-d-xylopyranoside
CAS 1643953-00-7C15H16O7
![[4,5-Diacetyloxy-2-(hydroxymethyl)-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl] acetate chemical structure, C22H24O11](/s/FKGDWIJBIHCCST-UHFFFAOYSA-N.svg)
[4,5-Diacetyloxy-2-(hydroxymethyl)-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl] acetate
C22H24O11
4-Methylumbelliferyl a-L-idopyranosiduronic acid 2-sulfate disodium salt
CAS 2181774-46-7C16H14Na2O12S
5,7-Dihydroxycoumarin 7-O-beta-D-glucopyranoside
CAS 944726-22-1C15H16O9
Disodium, 3,4-dihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxy-5-sulfonatooxyoxane-2-carboxylate
C16H14Na2O12S
2'-(4-Methylumbelliferyl)-a-D-N-acetylneuraminic acid sodium salt hydrate
CAS 1977472-73-3C21H26NNaO12
![Sodium (2R,4S,5R)-5-acetamido-4-hydroxy-2-(4-methyl-2-oxochromen-7-yl)oxy-6-[(1S,2S)-1,2,3-trihydroxypropyl]oxane-2-carboxylate chemical structure, C21H24NNaO11](/s/NNNXBDLJYKMDAI-UTAGNQDXSA-M.svg)
Sodium (2R,4S,5R)-5-acetamido-4-hydroxy-2-(4-methyl-2-oxochromen-7-yl)oxy-6-[(1S,2S)-1,2,3-trihydroxypropyl]oxane-2-carboxylate
C21H24NNaO11
4-Methylumbelliferyl-^a-L-iduronide sodium salt, synthetic, Affymetrix/USB
CAS 89157-94-8C16H15NaO9
![Sodium, [(2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methyl sulfate chemical structure, C18H20NNaO11S](/s/id-131668640.svg)
Sodium, [(2R,3S,4R,5R,6S)-5-acetamido-3,4-dihydroxy-6-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-2-yl]methyl sulfate
C18H20NNaO11S
alpha-Phenyl-2-piperidinemethanol (Mixture)
CAS 5583-35-7C24H26O12
![[(3R,6S)-4,5-Diacetyloxy-2-(hydroxymethyl)-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl] acetate chemical structure, C22H24O11](/s/FKGDWIJBIHCCST-MTDSMIIYSA-N.svg)
[(3R,6S)-4,5-Diacetyloxy-2-(hydroxymethyl)-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-3-yl] acetate
C22H24O11
4-Methyl-2-oxo-2H-1-benzopyran-7-yl 2,3,4,6-tetra-O-acetyl-alpha-D-galactopyranoside
CAS 67909-26-6C24H26O12
4-Methylumbelliferyl alpha-L-idopranosiduronic acid 2-sulphate sodium salt
C16H16NaO12S
4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt
C18H21NNaO11S
Methyl (2S,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxane-2-carboxylate
CAS 101014-65-7C23H24O12
![N-[7-[(2S,3S,4R,5S)-3,4-Dihydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy-8-methyl-2-oxochromen-3-yl]acetamide chemical structure, C20H25NO8](/s/KJAWXHNSLFJNTM-YEWFCNIMSA-N.svg)
N-[7-[(2S,3S,4R,5S)-3,4-Dihydroxy-5-methoxy-6,6-dimethyloxan-2-yl]oxy-8-methyl-2-oxochromen-3-yl]acetamide
C20H25NO8
Sodium (2S)-5-acetamido-4-hydroxy-2-(4-methyl-2-oxochromen-7-yl)oxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylate
C21H24NNaO11
- Erioside75872-12-7C15H16O10
- 17-Hydroxy-6-methoxy-pregna-4,6-diene-3,20-dione Acetate95975-51-2C18H20NNaO11S
- 4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-a-D-glucopyranoside Sodium Salt (>90%)153484-08-3C18H20NNaO11S
- Prionanthoside161842-81-5C17H18O10
- 8-Hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one dihydrate87125-20-0C15H20O11
- 7-(beta-D-Glucopyranosyloxy)-5-hydroxy-6-methoxy-2H-1-benzopyran-2-one141238-32-6C16H18O10
- Potassium [(3R,6S)-5-acetamido-3,4-dihydroxy-6-(4-methyl-2-oxochromen-7-yl)oxyoxan-2-yl]methyl sulfateC18H20KNO11S
- 4-Methyl-2-oxo-2H-1-benzopyran-7-yl 3,4,6-tri-O-acetyl-2-azido-2-deoxy-beta-D-galactopyranoside124167-44-8C22H23N3O10
- 6-Methoxy-3-(2-methylbut-3-en-2-yl)-2-oxo-2H-1-benzopyran-7-yl beta-D-glucopyranoside208333-72-6C21H26O9
- N-[(2S,5S)-2-(6-Chloro-4-methyl-2-oxochromen-7-yl)oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]acetamide1867162-08-0C18H20ClNO8
- 6-Chloro-4-methyl-7-[(2S,3R,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one1867162-06-8C16H17ClO8
- 6-Chloro-4-methyl-7-[(2S,3R,5R)-3,4,5-trihydroxyoxan-2-yl]oxychromen-2-one1867162-20-6C15H15ClO7
- 2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic Acid Methyl Ester131424-96-9C22H27NO11
- Methyl (2S,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-[2-oxo-4-(trifluoromethyl)chromen-7-yl]oxyoxane-2-carboxylate116523-81-0C23H21F3O12
- 8-(Fluoromethyl)-4-methyl-7-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chromen-2-one2411808-90-5C17H19FO8
- Methyl (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-oxo-4-(trifluoromethyl)chromen-7-yl]oxyoxane-2-carboxylate116523-83-2C17H15F3O9
- 4-Methylumbelliferyl a-D-arabinopyranoside119982-23-9C15H16O7
- 4-Trifluoromethylumbelliferyl a-D-N-acetylneuraminic acid195210-03-8C21H22F3NO11
- Sodium, [6-carboxy-4,5-dihydroxy-2-(4-methyl-2-oxo-chromen-7-yl)oxy-tetrahydropyran-3-yl] sulfateC16H15NaO12S
- Durianol A1941203-91-3C21H26O10
- DiFMU-|A-Gal2571070-06-7C16H16F2O8
Related scaffolds
Same ring framework with different atoms or bond orders
O=c1c(Oc2ccccc2)coc2ccccc12105 chemicals
O=c1c2ccccc2ncn1Cc1ccccc160 chemicals
O=S(=O)(c1ccccc1)N1CCc2ccccc2C150 chemicals
O=c1oc2ccccc2cc1Cc1ccccc143 chemicals
O=C1C=C(Nc2ccccc2)C(=O)c2ccccc2132 chemicals![Scaffold O=c1c(S(=O)(=O)c2ccccc2)c[nH]c2ccccc12](/scaffold/HKRPJNNJPHFLPC-UHFFFAOYSA-N/structure.svg)
O=c1c(S(=O)(=O)c2ccccc2)c[nH]c2ccccc1224 chemicals
c1ccc(Nc2ccc3ccccc3c2)cc123 chemicals
O=C(c1ccccc1)N1CCc2ccccc2C122 chemicals
c1ccc(Oc2cnc3ccccc3n2)cc121 chemicals
O=c1c2ccccc2cnn1Cc1ccccc120 chemicals
O=C1C(=Cc2ccccc2)CCc2ccccc2118 chemicals
O=C(c1ccccc1)c1ccc2c(c1)OCCO218 chemicals