Murcko scaffold
2H,6H,7H-Pyrazolo(3,4-d)pyridazin-7-one scaffold
40 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 40
- With full pages
- 4
Scaffold SMILES
O=c1[nH]ncc2cn[nH]c12
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]ncc2cn[nH]c12](/scaffold/QICFIUZWDPJRQF-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 40 of 40 chemicals
2H,6H,7H-Pyrazolo(3,4-d)pyridazin-7-one
CAS 219631-04-6C5H4N4O
![1-tert-Butyl-4-methyl-1,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one chemical structure, C10H14N4O, CAS 1105196-44-8](/s/BZFQZARONURLLI-UHFFFAOYSA-N.svg)
1-tert-Butyl-4-methyl-1,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one
CAS 1105196-44-8C10H14N4O
![1-tert-Butyl-4-(propan-2-yl)-1H,6H,7H-pyrazolo[3,4-d]pyridazin-7-one chemical structure, C12H18N4O, CAS 1105196-46-0](/s/LVDANKIJRLFMIV-UHFFFAOYSA-N.svg)
1-tert-Butyl-4-(propan-2-yl)-1H,6H,7H-pyrazolo[3,4-d]pyridazin-7-one
CAS 1105196-46-0C12H18N4O
![2-(1-(tert-Butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetamide chemical structure, C12H17N5O2, CAS 1171932-13-0](/s/JICMFPFQRKFISJ-UHFFFAOYSA-N.svg)
2-(1-(tert-Butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetamide
CAS 1171932-13-0C12H17N5O2
![1-(tert-Butyl)-4-methyl-6-propyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one chemical structure, C13H20N4O, CAS 1172966-78-7](/s/NBHYWCNHXPKOLI-UHFFFAOYSA-N.svg)
1-(tert-Butyl)-4-methyl-6-propyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one
CAS 1172966-78-7C13H20N4O
![1-(tert-Butyl)-6-butyl-4-methyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one chemical structure, C14H22N4O, CAS 1170279-96-5](/s/FJAQSJSCVWIUOZ-UHFFFAOYSA-N.svg)
1-(tert-Butyl)-6-butyl-4-methyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one
CAS 1170279-96-5C14H22N4O
![1-(tert-Butyl)-6-isopentyl-4-methyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one chemical structure, C15H24N4O, CAS 1170628-14-4](/s/REZBWRUOQMABNR-UHFFFAOYSA-N.svg)
1-(tert-Butyl)-6-isopentyl-4-methyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one
CAS 1170628-14-4C15H24N4O
![6-Allyl-1-(tert-butyl)-4-methyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one chemical structure, C13H18N4O, CAS 1172395-61-7](/s/BBJHOTWKPMFHRW-UHFFFAOYSA-N.svg)
6-Allyl-1-(tert-butyl)-4-methyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one
CAS 1172395-61-7C13H18N4O
![2-{1-tert-Butyl-4-methyl-7-oxo-1H,6H,7H-pyrazolo[3,4-d]pyridazin-6-yl}-N,N-diethylacetamide chemical structure, C16H25N5O2, CAS 1170415-47-0](/s/LZXICSXHFJCUJA-UHFFFAOYSA-N.svg)
2-{1-tert-Butyl-4-methyl-7-oxo-1H,6H,7H-pyrazolo[3,4-d]pyridazin-6-yl}-N,N-diethylacetamide
CAS 1170415-47-0C16H25N5O2
![Ethyl 2-(1-(tert-butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetate chemical structure, C14H20N4O3, CAS 1171150-80-3](/s/HXQFHKCMAFPOTL-UHFFFAOYSA-N.svg)
Ethyl 2-(1-(tert-butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetate
CAS 1171150-80-3C14H20N4O3
![2-(1-(tert-Butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N-propylacetamide chemical structure, C15H23N5O2, CAS 1172750-08-1](/s/HPKJRKYMRAVOBS-UHFFFAOYSA-N.svg)
2-(1-(tert-Butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N-propylacetamide
CAS 1172750-08-1C15H23N5O2
![2-{1-tert-Butyl-4-methyl-7-oxo-1H,6H,7H-pyrazolo[3,4-d]pyridazin-6-yl}-N-(propan-2-yl)acetamide chemical structure, C15H23N5O2, CAS 1172800-94-0](/s/JPJPLNZCPXHVOR-UHFFFAOYSA-N.svg)
2-{1-tert-Butyl-4-methyl-7-oxo-1H,6H,7H-pyrazolo[3,4-d]pyridazin-6-yl}-N-(propan-2-yl)acetamide
CAS 1172800-94-0C15H23N5O2
![N-(tert-Butyl)-2-(1-(tert-butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetamide chemical structure, C16H25N5O2, CAS 1171512-63-2](/s/ZKWOVYCQBKFNIS-UHFFFAOYSA-N.svg)
N-(tert-Butyl)-2-(1-(tert-butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetamide
CAS 1171512-63-2C16H25N5O2
![2-{1-tert-Butyl-4-methyl-7-oxo-1H,6H,7H-pyrazolo[3,4-d]pyridazin-6-yl}-N-(2-methoxyethyl)acetamide chemical structure, C15H23N5O3, CAS 1172516-49-2](/s/KDNCETHJSLCCGZ-UHFFFAOYSA-N.svg)
2-{1-tert-Butyl-4-methyl-7-oxo-1H,6H,7H-pyrazolo[3,4-d]pyridazin-6-yl}-N-(2-methoxyethyl)acetamide
CAS 1172516-49-2C15H23N5O3
![2-(1-(tert-Butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N,N-diisopropylacetamide chemical structure, C18H29N5O2, CAS 1173079-02-1](/s/VVCNNZGHAHMUTL-UHFFFAOYSA-N.svg)
2-(1-(tert-Butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N,N-diisopropylacetamide
CAS 1173079-02-1C18H29N5O2
![N-Allyl-2-(1-(tert-butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetamide chemical structure, C15H21N5O2, CAS 1171858-81-3](/s/KPKFZSDIQDOYJU-UHFFFAOYSA-N.svg)
N-Allyl-2-(1-(tert-butyl)-4-methyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetamide
CAS 1171858-81-3C15H21N5O2
![1-(tert-Butyl)-4,6-diisopropyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one chemical structure, C15H24N4O, CAS 1171184-64-7](/s/MWVLYLSLKDTABT-UHFFFAOYSA-N.svg)
1-(tert-Butyl)-4,6-diisopropyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one
CAS 1171184-64-7C15H24N4O
![2-(1-(tert-Butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetamide chemical structure, C14H21N5O2, CAS 1171085-25-8](/s/DXZDSJLZQJQBRJ-UHFFFAOYSA-N.svg)
2-(1-(tert-Butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetamide
CAS 1171085-25-8C14H21N5O2
![1-(tert-Butyl)-4-isopropyl-6-propyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one chemical structure, C15H24N4O, CAS 1173084-76-8](/s/SCOJMELNJZQKSH-UHFFFAOYSA-N.svg)
1-(tert-Butyl)-4-isopropyl-6-propyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one
CAS 1173084-76-8C15H24N4O
![6-(sec-Butyl)-1-(tert-butyl)-4-isopropyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one chemical structure, C16H26N4O, CAS 1171517-60-4](/s/UKCJECQHMSWGAQ-UHFFFAOYSA-N.svg)
6-(sec-Butyl)-1-(tert-butyl)-4-isopropyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one
CAS 1171517-60-4C16H26N4O
![2-(1-(tert-Butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N,N-diethylacetamide chemical structure, C18H29N5O2, CAS 1171325-99-7](/s/URDPFGNSBWMSNU-UHFFFAOYSA-N.svg)
2-(1-(tert-Butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N,N-diethylacetamide
CAS 1171325-99-7C18H29N5O2
![2-(1-(tert-Butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N-methylacetamide chemical structure, C15H23N5O2, CAS 1171199-57-7](/s/FUXILDLBAWCBCR-UHFFFAOYSA-N.svg)
2-(1-(tert-Butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N-methylacetamide
CAS 1171199-57-7C15H23N5O2
![2-(1-(tert-Butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N-propylacetamide chemical structure, C17H27N5O2, CAS 1172892-15-7](/s/QABGAXUZSGQJAT-UHFFFAOYSA-N.svg)
2-(1-(tert-Butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N-propylacetamide
CAS 1172892-15-7C17H27N5O2
![N-tert-Butyl-2-[1-tert-butyl-7-oxo-4-(propan-2-yl)-1H,6H,7H-pyrazolo[3,4-d]pyridazin-6-yl]acetamide chemical structure, C18H29N5O2, CAS 1172877-65-4](/s/JZWPEADOSJEIDY-UHFFFAOYSA-N.svg)
N-tert-Butyl-2-[1-tert-butyl-7-oxo-4-(propan-2-yl)-1H,6H,7H-pyrazolo[3,4-d]pyridazin-6-yl]acetamide
CAS 1172877-65-4C18H29N5O2
- 2-(1-(tert-Butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)-N-(2-methoxyethyl)acetamide1171985-64-0C17H27N5O3
- N-Allyl-2-(1-(tert-butyl)-4-isopropyl-7-oxo-1H-pyrazolo[3,4-d]pyridazin-6(7H)-yl)acetamide1171321-59-7C17H25N5O2
- 2-Methyl-2H,6H,7H-pyrazolo[3,4-d]pyridazin-7-one81305-93-3C6H6N4O
- 2,6-Dimethyl-2,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one69792-74-1C7H8N4O
- 6-Ethyl-2-methyl-2H,6H,7H-pyrazolo[3,4-d]pyridazin-7-one1823371-43-2C8H10N4O
- 2,6-Diethyl-2H,6H,7H-pyrazolo[3,4-d]pyridazin-7-one1823934-76-4C9H12N4O
- 1-Methyl-1H-pyrazolo[3,4-d]pyridazin-7(6H)-one81305-92-2C6H6N4O
- 1,3-Dimethyl-1H-pyrazolo[3,4-d]pyridazin-7-ol1909337-15-0C7H8N4O
- 1,4-Dimethyl-1H-pyrazolo[3,4-d]pyridazin-7-ol2091778-76-4C7H8N4O
- 6-Methyl-1H,6H,7H-pyrazolo[3,4-d]pyridazin-7-one69792-72-9C6H6N4O
- 4-Isopropyl-1,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one2320377-13-5C8H10N4O
- 3,4-Dimethyl-2,6-dihydro-7H-pyrazolo[3,4-d]pyridazin-7-one91912-55-9C7H8N4O
- 3-Methoxy-1H-pyrazolo[3,4-d]pyridazin-7-ol2920143-86-6C6H6N4O2
- 3-Isopropyl-1-methyl-1,6-dihydro-7H-pyrazolo[3,4-D]pyridazin-7-one2783962-29-6C9H12N4O
- 4-Amino-3-bromo-1,6-dihydropyrazolo[3,4-d]pyridazin-7-one2762044-81-3C5H4BrN5O
- 4-Amino-1,6-dihydropyrazolo[3,4-d]pyridazin-7-one2762044-80-2C5H5N5O
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