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Murcko scaffold

Ring system with 2 rings and 18 atoms

6 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
6
With full pages
6
Scaffold SMILES

O=C1NCCCC1C(=O)NN=Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NCCCC1C(=O)NN=Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

N'-[(E)-(3-Nitrophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide chemical structure, C13H14N4O4, CAS 676484-23-4
N'-[(E)-(3-Nitrophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide
CAS 676484-23-4C13H14N4O4
N'-[(E)-(3-Chlorophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide chemical structure, C13H14ClN3O2, CAS 294196-14-8
N'-[(E)-(3-Chlorophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide
CAS 294196-14-8C13H14ClN3O2
N'-[(E)-(2-Nitrophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide chemical structure, C13H14N4O4, CAS 318271-73-7
N'-[(E)-(2-Nitrophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide
CAS 318271-73-7C13H14N4O4
N'-[(E)-(4-Chlorophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide chemical structure, C13H14ClN3O2, CAS 282103-47-3
N'-[(E)-(4-Chlorophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide
CAS 282103-47-3C13H14ClN3O2
N'-[(E)-(4-Butoxyphenyl)methylidene]-2-oxopiperidine-3-carbohydrazide chemical structure, C17H23N3O3, CAS 315194-58-2
N'-[(E)-(4-Butoxyphenyl)methylidene]-2-oxopiperidine-3-carbohydrazide
CAS 315194-58-2C17H23N3O3
N'-[(E)-(2-Hydroxy-5-nitrophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide chemical structure, C13H14N4O5, CAS 318271-74-8
N'-[(E)-(2-Hydroxy-5-nitrophenyl)methylidene]-2-oxopiperidine-3-carbohydrazide
CAS 318271-74-8C13H14N4O5