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Murcko scaffold

Ring system with 3 rings and 19 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
11
With full pages
3
Scaffold SMILES

O=C(NN=Cc1ccccc1)c1n[nH]c2c1CCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NN=Cc1ccccc1)c1n[nH]c2c1CCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

(Z)-N'-(3-Methoxybenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C15H16N4O2, CAS 305355-20-8
(Z)-N'-(3-Methoxybenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 305355-20-8C15H16N4O2
N'-[(E)-(2,5-Dimethoxyphenyl)methylidene]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C16H18N4O3, CAS 306986-78-7
N'-[(E)-(2,5-Dimethoxyphenyl)methylidene]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 306986-78-7C16H18N4O3
(E)-N'-(4-(Dimethylamino)benzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C16H19N5O, CAS 1477483-21-8
(E)-N'-(4-(Dimethylamino)benzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 1477483-21-8C16H19N5O
(E)-N'-(2,4-Dichlorobenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C14H12Cl2N4O, CAS 331234-51-6
(E)-N'-(2,4-Dichlorobenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 331234-51-6C14H12Cl2N4O
N'-[(E)-(3-Methoxyphenyl)methylidene]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C15H16N4O2
N'-[(E)-(3-Methoxyphenyl)methylidene]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
C15H16N4O2
(E)-N'-(3,4,5-Trimethoxybenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C17H20N4O4, CAS 306986-79-8
(E)-N'-(3,4,5-Trimethoxybenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 306986-79-8C17H20N4O4
N'-[1-(4-Hexylphenyl)ethylidene]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C21H28N4O, CAS 331418-83-8
N'-[1-(4-Hexylphenyl)ethylidene]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 331418-83-8C21H28N4O
(E)-N'-(4-Bromobenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C14H13BrN4O, CAS 331234-53-8
(E)-N'-(4-Bromobenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 331234-53-8C14H13BrN4O
N'-[(E)-(4-Hydroxyphenyl)methylidene]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C14H14N4O2, CAS 1477482-85-1
N'-[(E)-(4-Hydroxyphenyl)methylidene]-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 1477482-85-1C14H14N4O2
(E)-N'-(2-Hydroxybenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C14H14N4O2, CAS 1477482-83-9
(E)-N'-(2-Hydroxybenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 1477482-83-9C14H14N4O2
(E)-N'-(3-Ethoxy-2-hydroxybenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide chemical structure, C16H18N4O3, CAS 306986-72-1
(E)-N'-(3-Ethoxy-2-hydroxybenzylidene)-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
CAS 306986-72-1C16H18N4O3