Murcko scaffold
Ring system with 1 ring and 44 atoms
57 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 44
- Chemicals
- 57
- With full pages
- 18
Scaffold SMILES
O=C1CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CNC(=O)CN1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 57 chemicals
Dihydrocyclosporin D
CAS 63775-91-7C63H115N11O12
Dihydrocyclosporin C
CAS 63556-15-0C62H113N11O13
Cyclosporin A, 6-(threo-3-hydroxy-N-methyl-L-leucine)-
CAS 154334-72-2C59H107N11O12
(MeLeu(3-OH)1, MeAla4,6)-CsA
CAS 166445-47-2C53H95N11O12
Cyclosporin A, 5-(N-methyl-D-valine)-6-(threo-3-hydroxy-N-methyl-L-leucine)-
CAS 166733-03-5C59H107N11O12
8-Hydroxy-6,7-dihydro-(4-(2-butenyl)-4,N-dimethylthreonine)cyclosporin
CAS 121886-75-7C62H113N11O13
Valspodar
CAS 121584-18-7C63H111N11O12
Cyclosporin A
CAS 59865-13-3C62H111N11O12
Cyclosporin impurity 36
CAS 107335-26-2C62H111N11O13
Cyclosporin C
CAS 59787-61-0C62H111N11O13
Cyclosporin D
CAS 63775-96-2C63H113N11O12
Orb1221784
CAS 79217-60-0C62H111N11O12
Oxeclosporin
CAS 135548-15-1C64H115N11O14
Cyclosporin A, MeAla(6)-
CAS 111710-61-3C59H105N11O12
Cyclosporin A, 4-(2-butenyl)-4,4,N-trimethylthreonine(1)-
CAS 114865-22-4C63H113N11O12
Cyclosporine metabolite M21
CAS 89270-23-5C61H109N11O12
Cyclosporine metabolite M17
CAS 89270-28-0C62H111N11O13
N-methyl-valyl-4-cyclosporin A
CAS 159605-70-6C61H109N11O12
(4-Hydroxy-N-methyl-L-leucine)cyclosporine
CAS 89270-25-7C62H111N11O13
8-(N-Methylalanine)cyclosporin A
CAS 108466-41-7C63H113N11O12
9-Hydroxy-9-desmethylcyclosporine
CAS 132362-39-1C61H109N11O13
(Melle-4)cyclosporin
CAS 143205-42-9C62H111N11O12
Geclosporin
CAS 74436-00-3C63H113N11O12
Cyclosporin H
CAS 83602-39-5C62H111N11O12
- Scy-635210759-10-7C66H120N12O13S
- 19 suppliersVoclosporin515814-01-4C63H111N11O12
- FR 901459153049-50-4C62H111N11O13
- Orb3180523164028-89-1C64H114N14O13
- Cyclosporin A-derivative 3121584-34-7C63H111N11O12
- UNIL-088473545-11-8C73H128N13O22P
- 6-[(3R,4R)-3-(Acetyloxy)-N,4-dimethyl-6-oxo-L-norleucine] Cyclosporin A121584-52-9C62H109N11O14
- Alisporivir254435-95-5C63H113N11O12
- 4 suppliersCyclosporin B63775-95-1C61H109N11O12
- Cyclosporin F83574-28-1C62H111N11O11
- 2-D-Serinecyclosporin A84328-80-3C62H111N11O13
- 3 suppliersDihydrocyclosporin A59865-15-5C62H113N11O12
- Cyclosporin impurity 13437611-17-1C61H109N11O12
- Cyclosporin A sulfate121673-00-5C62H111N11O15S
- 30-Ethyl-33-[(E)-1-hydroxy-2-methylhex-4-enyl]-1,4,10,12,15,19,25,28-octamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undeconeC61H109N11O12
- 6-[(2S,3R,4R,6E)-3-(Acetyloxy)-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A515814-02-5C65H113N11O13
- cyclo[Ala-D-Ala-N(Me)Leu-Leu-N(Me)Val-N(Me)Bmt(E)-Thr-D-N(Me)Ala-N(Me)Thr(Me)-Leu-N(Me)Leu]935735-70-9C62H111N11O14
- 2 suppliersDihydrocyclosporin H83602-88-4C62H113N11O12
- 1 suppliersCyclosporin E63798-73-2C61H109N11O12
- 2 suppliersCyclosporin U108027-45-8C61H109N11O12
- 1 suppliersCyclosporin T108027-44-7C61H109N11O12
- Cyclosporin L108027-39-0C61H109N11O12
- 1 suppliersCyclosporin V108027-46-9C63H113N11O12
- Rencofilstat1383420-08-3C67H122N12O13
Related scaffolds
Same ring framework with different atoms or bond orders
