CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 21 atoms

7 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
7
With full pages
1
Scaffold SMILES

c1ccc(C2CC(N3CCNCC3)c3ccccc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(C2CC(N3CCNCC3)c3ccccc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Tefludazine chemical structure, C22H24F4N2O, CAS 80273-79-6
Tefludazine
CAS 80273-79-6C22H24F4N2O
(3-(3,4-Dichlorophenyl)indan-1-yl)-4-methylpiperazine chemical structure, C20H22Cl2N2, CAS 85663-20-3
(3-(3,4-Dichlorophenyl)indan-1-yl)-4-methylpiperazine
CAS 85663-20-3C20H22Cl2N2
Zicronapine succinate chemical structure, C26H33ClN2O4, CAS 846061-36-7
Zicronapine succinate
CAS 846061-36-7C26H33ClN2O4
Zicronapine chemical structure, C22H27ClN2, CAS 170381-16-5
Zicronapine
CAS 170381-16-5C22H27ClN2
trans-4-(3-(4-Fluorophenyl)-2,3-dihydro-6-(trifluoromethyl)-1H-inden-1-yl)piperazine-1-ethanol dihydrochloride chemical structure, C22H26Cl2F4N2O, CAS 85118-23-6
trans-4-(3-(4-Fluorophenyl)-2,3-dihydro-6-(trifluoromethyl)-1H-inden-1-yl)piperazine-1-ethanol dihydrochloride
CAS 85118-23-6C22H26Cl2F4N2O
Zicronapine-D8 chemical structure, C22H27ClN2, CAS 1416227-06-9
Zicronapine-D8
CAS 1416227-06-9C22H27ClN2
Zicronapine fumarate chemical structure, C26H31ClN2O4, CAS 170381-17-6
Zicronapine fumarate
CAS 170381-17-6C26H31ClN2O4