CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 23 atoms

6 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
23
Chemicals
6
With full pages
5
Scaffold SMILES

O=C1OCc2cc3cc4c(cc3c(-c3ccccc3)c21)OCO4

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OCc2cc3cc4c(cc3c(-c3ccccc3)c21)OCO4

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

5-Methoxydehydropodophyllotoxin chemical structure, C23H20O9, CAS 151703-06-9
5-Methoxydehydropodophyllotoxin
CAS 151703-06-9C23H20O9
9-(3,4-Dimethoxyphenyl)-5-hydroxy-6H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one chemical structure, C21H16O7, CAS 53965-06-3
9-(3,4-Dimethoxyphenyl)-5-hydroxy-6H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one
CAS 53965-06-3C21H16O7
Chinensinaphthol methyl ether chemical structure, C22H18O7, CAS 53965-11-0
Chinensinaphthol methyl ether
CAS 53965-11-0C22H18O7
Dehydropodophyllotoxin chemical structure, C22H18O8, CAS 42123-27-3
Dehydropodophyllotoxin
CAS 42123-27-3C22H18O8
4'-Demethyldehydropodophyllotoxin chemical structure, C21H16O8, CAS 117669-31-5
4'-Demethyldehydropodophyllotoxin
CAS 117669-31-5C21H16O8
Etoposide EP impurity Q chemical structure, C21H16O7, CAS 153975-26-9
Etoposide EP impurity Q
CAS 153975-26-9C21H16O7