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Murcko scaffold

4H,5H,6H,7H-Pyrazolo[1,5-a]pyridin-4-one scaffold

40 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
40
With full pages
3
Scaffold SMILES

O=C1CCCn2nccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4H,5H,6H,7H-Pyrazolo[1,5-a]pyridin-4-one page
Murcko scaffold O=C1CCCn2nccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

4H,5H,6H,7H-Pyrazolo[1,5-a]pyridin-4-one chemical structure, C7H8N2O, CAS 197094-19-2
4H,5H,6H,7H-Pyrazolo[1,5-a]pyridin-4-one
CAS 197094-19-2C7H8N2O
4-Oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-2,5-dicarboxylic acid diethyl ester chemical structure, C13H16N2O5, CAS 459157-16-5
4-Oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-2,5-dicarboxylic acid diethyl ester
CAS 459157-16-5C13H16N2O5
4-Oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyridine-2-carboxylic acid chemical structure, C8H8N2O3, CAS 459157-20-1
4-Oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyridine-2-carboxylic acid
CAS 459157-20-1C8H8N2O3
4-Oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-2-carboxylic acid ethyl ester chemical structure, C10H12N2O3, CAS 459157-22-3
4-Oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine-2-carboxylic acid ethyl ester
CAS 459157-22-3C10H12N2O3
(4-Oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-2-yl)-carbamic acid tert-butyl ester chemical structure, C12H17N3O3, CAS 1221885-30-8
(4-Oxo-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridin-2-yl)-carbamic acid tert-butyl ester
CAS 1221885-30-8C12H17N3O3
2-Amino-6,7-dihydropyrazolo[1,5-a]pyridin-4(5H)-one chemical structure, C7H9N3O, CAS 1221885-31-9
2-Amino-6,7-dihydropyrazolo[1,5-a]pyridin-4(5H)-one
CAS 1221885-31-9C7H9N3O
Methyl 3-nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-2-carboxylate chemical structure, C9H9N3O5, CAS 1189579-80-3
Methyl 3-nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-2-carboxylate
CAS 1189579-80-3C9H9N3O5
3-Nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-2-carboxylic acid chemical structure, C8H7N3O5, CAS 1189579-78-9
3-Nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-2-carboxylic acid
CAS 1189579-78-9C8H7N3O5
3-Nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-2-carboxamide chemical structure, C8H8N4O4, CAS 1189579-79-0
3-Nitro-4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-2-carboxamide
CAS 1189579-79-0C8H8N4O4
Methyl 4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyridine-2-carboxylate chemical structure, C9H10N2O3, CAS 1708268-35-2
Methyl 4-oxo-4H,5H,6H,7H-pyrazolo[1,5-a]pyridine-2-carboxylate
CAS 1708268-35-2C9H10N2O3
2-Methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one chemical structure, C8H10N2O, CAS 1510352-72-3
2-Methyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one
CAS 1510352-72-3C8H10N2O
3-Amino-6,7-dihydropyrazolo[1,5-a]pyridin-4(5H)-one chemical structure, C7H9N3O, CAS 1539546-09-2
3-Amino-6,7-dihydropyrazolo[1,5-a]pyridin-4(5H)-one
CAS 1539546-09-2C7H9N3O
3-Methyl-6,7-dihydropyrazolo[1,5-a]pyridin-4(5H)-one chemical structure, C8H10N2O, CAS 1547108-53-1
3-Methyl-6,7-dihydropyrazolo[1,5-a]pyridin-4(5H)-one
CAS 1547108-53-1C8H10N2O
3-Bromo-6,7-dihydropyrazolo[1,5-A]pyridin-4(5H)-one chemical structure, C7H7BrN2O, CAS 1784026-76-1
3-Bromo-6,7-dihydropyrazolo[1,5-A]pyridin-4(5H)-one
CAS 1784026-76-1C7H7BrN2O
5,5-Dimethyl-6,7-dihydropyrazolo[1,5-a]pyridin-4-one chemical structure, C9H12N2O, CAS 2057512-10-2
5,5-Dimethyl-6,7-dihydropyrazolo[1,5-a]pyridin-4-one
CAS 2057512-10-2C9H12N2O
Ethyl 4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyridine-5-carboxylate chemical structure, C10H12N2O3, CAS 2057509-08-5
Ethyl 4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyridine-5-carboxylate
CAS 2057509-08-5C10H12N2O3
2-(Difluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one chemical structure, C8H8F2N2O, CAS 2092330-60-2
2-(Difluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one
CAS 2092330-60-2C8H8F2N2O
2-Fluoro-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one chemical structure, C7H7FN2O, CAS 2090480-21-8
2-Fluoro-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one
CAS 2090480-21-8C7H7FN2O
2-Ethyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one chemical structure, C9H12N2O, CAS 2092330-71-5
2-Ethyl-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one
CAS 2092330-71-5C9H12N2O
2-(Trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one chemical structure, C8H7F3N2O, CAS 2092598-78-0
2-(Trifluoromethyl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one
CAS 2092598-78-0C8H7F3N2O
2-(Propan-2-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one chemical structure, C10H14N2O, CAS 2090480-27-4
2-(Propan-2-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyridin-4-one
CAS 2090480-27-4C10H14N2O
Ethyl 3-bromo-4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyridine-5-carboxylate chemical structure, C10H11BrN2O3, CAS 2238820-05-6
Ethyl 3-bromo-4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyridine-5-carboxylate
CAS 2238820-05-6C10H11BrN2O3
3-Amino-5,5-dimethyl-6,7-dihydropyrazolo[1,5-a]pyridin-4(5H)-one chemical structure, C9H13N3O, CAS 2289603-93-4
3-Amino-5,5-dimethyl-6,7-dihydropyrazolo[1,5-a]pyridin-4(5H)-one
CAS 2289603-93-4C9H13N3O
3-Nitro-6,7-dihydro-5H-pyrazolo[1,5-a]pyridin-4-one chemical structure, C7H7N3O3, CAS 2289603-94-5
3-Nitro-6,7-dihydro-5H-pyrazolo[1,5-a]pyridin-4-one
CAS 2289603-94-5C7H7N3O3