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Murcko scaffold

1H-Pyrazolo[3,4-b]pyridine-3,6(2H,7H)-dione scaffold

9 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
9
With full pages
4
Scaffold SMILES

O=c1ccc2c(=O)[nH][nH]c2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1H-Pyrazolo[3,4-b]pyridine-3,6(2H,7H)-dione page
Murcko scaffold O=c1ccc2c(=O)[nH][nH]c2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

6-Hydroxy-4-methyl-1,2-dihydro-3H-pyrazolo(3,4-b)pyridin-3-one chemical structure, C7H7N3O2, CAS 28491-58-9
6-Hydroxy-4-methyl-1,2-dihydro-3H-pyrazolo(3,4-b)pyridin-3-one
CAS 28491-58-9C7H7N3O2
Ethyl 2,3,6,7-tetrahydro-1,5-dimethyl-3,6-dioxo-1H-pyrazolo(3,4-b)pyridine-4-carboxylate chemical structure, C11H13N3O4, CAS 71290-74-9
Ethyl 2,3,6,7-tetrahydro-1,5-dimethyl-3,6-dioxo-1H-pyrazolo(3,4-b)pyridine-4-carboxylate
CAS 71290-74-9C11H13N3O4
1H-Pyrazolo[3,4-b]pyridine-3,6(2H,7H)-dione chemical structure, C6H5N3O2, CAS 512782-64-8
1H-Pyrazolo[3,4-b]pyridine-3,6(2H,7H)-dione
CAS 512782-64-8C6H5N3O2
3-{1,4-Dimethyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}propanoic acid chemical structure, C11H13N3O4, CAS 1050885-22-7
3-{1,4-Dimethyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}propanoic acid
CAS 1050885-22-7C11H13N3O4
2-{1,4-Dimethyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}acetic acid chemical structure, C10H11N3O4, CAS 1087784-33-5
2-{1,4-Dimethyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}acetic acid
CAS 1087784-33-5C10H11N3O4
2-(6-Hydroxy-4-methyl-3-oxo-1H,2H,3H-pyrazolo(3,4-b)pyridin-5-yl)acetic acid chemical structure, C9H9N3O4, CAS 1240529-02-5
2-(6-Hydroxy-4-methyl-3-oxo-1H,2H,3H-pyrazolo(3,4-b)pyridin-5-yl)acetic acid
CAS 1240529-02-5C9H9N3O4
3-{4-Methyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}propanoic acid chemical structure, C10H11N3O4, CAS 1235439-50-5
3-{4-Methyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}propanoic acid
CAS 1235439-50-5C10H11N3O4
3-{4-Methyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}propanoic acid hydrochloride chemical structure, C10H12ClN3O4, CAS 1251922-88-9
3-{4-Methyl-3,6-dioxo-1H,2H,3H,6H,7H-pyrazolo[3,4-b]pyridin-5-yl}propanoic acid hydrochloride
CAS 1251922-88-9C10H12ClN3O4
3,6-Dioxo-2,3,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid chemical structure, C7H5N3O4, CAS 1781582-45-3
3,6-Dioxo-2,3,6,7-tetrahydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
CAS 1781582-45-3C7H5N3O4