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Murcko scaffold

Ring system with 2 rings and 13 atoms

71 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
71
With full pages
8
Scaffold SMILES

c1ccc(OCc2cnoc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(OCc2cnoc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 71 of 71 chemicals

3,5-Dimethyl-4-[(3-nitrophenoxy)methyl]isoxazole chemical structure, C12H12N2O4, CAS 951923-69-6
3,5-Dimethyl-4-[(3-nitrophenoxy)methyl]isoxazole
CAS 951923-69-6C12H12N2O4
4-[(2-Methoxyphenoxy)methyl]-5-methylisoxazole-3-carboxylic acid chemical structure, C13H13NO5, CAS 932894-19-4
4-[(2-Methoxyphenoxy)methyl]-5-methylisoxazole-3-carboxylic acid
CAS 932894-19-4C13H13NO5
4-[(4-Cyanophenoxy)methyl]-5-methylisoxazole-3-carboxylic acid chemical structure, C13H10N2O4, CAS 1142202-02-5
4-[(4-Cyanophenoxy)methyl]-5-methylisoxazole-3-carboxylic acid
CAS 1142202-02-5C13H10N2O4
(2E)-3-{4-[(3,5-Dimethyl-1,2-oxazol-4-yl)methoxy]phenyl}prop-2-enoic acid chemical structure, C15H15NO4, CAS 1050884-51-9
(2E)-3-{4-[(3,5-Dimethyl-1,2-oxazol-4-yl)methoxy]phenyl}prop-2-enoic acid
CAS 1050884-51-9C15H15NO4
(2E)-3-{2-[(3,5-Dimethylisoxazol-4-yl)methoxy]phenyl}acrylic acid chemical structure, C15H15NO4, CAS 1087796-95-9
(2E)-3-{2-[(3,5-Dimethylisoxazol-4-yl)methoxy]phenyl}acrylic acid
CAS 1087796-95-9C15H15NO4
(2E)-3-{3-[(3,5-Dimethylisoxazol-4-yl)methoxy]phenyl}acrylic acid chemical structure, C15H15NO4, CAS 1087798-90-0
(2E)-3-{3-[(3,5-Dimethylisoxazol-4-yl)methoxy]phenyl}acrylic acid
CAS 1087798-90-0C15H15NO4
(4-((Dimethyl-1,2-oxazol-4-yl)methoxy)phenyl)methanamine chemical structure, C13H16N2O2, CAS 1178816-89-1
(4-((Dimethyl-1,2-oxazol-4-yl)methoxy)phenyl)methanamine
CAS 1178816-89-1C13H16N2O2
1-[(1-Cyano-1,2-dimethylpropyl)carbamoyl]ethyl 3-{4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]-3-methoxyphenyl}prop-2-enoate chemical structure, C25H31N3O6, CAS 1087778-46-8
1-[(1-Cyano-1,2-dimethylpropyl)carbamoyl]ethyl 3-{4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]-3-methoxyphenyl}prop-2-enoate
CAS 1087778-46-8C25H31N3O6
Benzoic acid, 3-chloro-4-[(3,5-dimethyl-4-isoxazolyl)methoxy]- chemical structure, C13H12ClNO4, CAS 1303743-40-9
Benzoic acid, 3-chloro-4-[(3,5-dimethyl-4-isoxazolyl)methoxy]-
CAS 1303743-40-9C13H12ClNO4
4-[(3,5-Dimethyl-4-isoxazolyl)methoxy]-3,5-dimethylbenzenemethanamine chemical structure, C15H20N2O2, CAS 1179080-57-9
4-[(3,5-Dimethyl-4-isoxazolyl)methoxy]-3,5-dimethylbenzenemethanamine
CAS 1179080-57-9C15H20N2O2
3-Chloro-4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]benzaldehyde chemical structure, C13H12ClNO3, CAS 1285130-15-5
3-Chloro-4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]benzaldehyde
CAS 1285130-15-5C13H12ClNO3
4-[(2-Nitrophenoxy)methyl]-1,2-oxazole chemical structure, C10H8N2O4, CAS 872611-08-0
4-[(2-Nitrophenoxy)methyl]-1,2-oxazole
CAS 872611-08-0C10H8N2O4
Benzeneacetic acid, 4-[(3,5-dimethyl-4-isoxazolyl)methoxy]-3-fluoro- chemical structure, C14H14FNO4, CAS 1443325-34-5
Benzeneacetic acid, 4-[(3,5-dimethyl-4-isoxazolyl)methoxy]-3-fluoro-
CAS 1443325-34-5C14H14FNO4
Methyl 4-[(4-amino-2-chlorophenoxy)methyl]-5-methylisoxazole-3-carboxylate hydrochloride chemical structure, C13H14Cl2N2O4, CAS 1431964-97-4
Methyl 4-[(4-amino-2-chlorophenoxy)methyl]-5-methylisoxazole-3-carboxylate hydrochloride
CAS 1431964-97-4C13H14Cl2N2O4
Methyl 3-((3,5-dimethylisoxazol-4-yl)methoxy)benzoate chemical structure, C14H15NO4, CAS 1987279-07-1
Methyl 3-((3,5-dimethylisoxazol-4-yl)methoxy)benzoate
CAS 1987279-07-1C14H15NO4
2-[(3-Ethyl-5-methyl-1,2-oxazol-4-yl)methoxy]-5-fluorobenzaldehyde chemical structure, C14H14FNO3, CAS 2094469-10-8
2-[(3-Ethyl-5-methyl-1,2-oxazol-4-yl)methoxy]-5-fluorobenzaldehyde
CAS 2094469-10-8C14H14FNO3
tert-Butyl (2E)-3-{4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]-3-methoxyphenyl}prop-2-enoate chemical structure, C20H25NO5, CAS 2138802-97-6
tert-Butyl (2E)-3-{4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]-3-methoxyphenyl}prop-2-enoate
CAS 2138802-97-6C20H25NO5
tert-Butyl (2E)-3-{4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]phenyl}prop-2-enoate chemical structure, C19H23NO4, CAS 2138820-76-3
tert-Butyl (2E)-3-{4-[(3,5-dimethyl-1,2-oxazol-4-yl)methoxy]phenyl}prop-2-enoate
CAS 2138820-76-3C19H23NO4
4-[(4-Amino-2-chlorophenoxy)methyl]-5-methyl-1,2-oxazole-3-carboxylic acid chemical structure, C12H11ClN2O4, CAS 2639443-39-1
4-[(4-Amino-2-chlorophenoxy)methyl]-5-methyl-1,2-oxazole-3-carboxylic acid
CAS 2639443-39-1C12H11ClN2O4
4-[(4-{[(tert-Butoxy)carbonyl]amino}-2-chlorophenoxy)methyl]-5-methyl-1,2-oxazole-3-carboxylic acid chemical structure, C17H19ClN2O6, CAS 2639463-15-1
4-[(4-{[(tert-Butoxy)carbonyl]amino}-2-chlorophenoxy)methyl]-5-methyl-1,2-oxazole-3-carboxylic acid
CAS 2639463-15-1C17H19ClN2O6
Ethyl 4-[(4-amino-2-chlorophenoxy)methyl]-5-methyl-1,2-oxazole-3-carboxylate chemical structure, C14H15ClN2O4, CAS 2639459-03-1
Ethyl 4-[(4-amino-2-chlorophenoxy)methyl]-5-methyl-1,2-oxazole-3-carboxylate
CAS 2639459-03-1C14H15ClN2O4
tert-Butyl 4-[(4-amino-2-chlorophenoxy)methyl]-5-methyl-1,2-oxazole-3-carboxylate chemical structure, C16H19ClN2O4, CAS 2639409-85-9
tert-Butyl 4-[(4-amino-2-chlorophenoxy)methyl]-5-methyl-1,2-oxazole-3-carboxylate
CAS 2639409-85-9C16H19ClN2O4
4-{[2-Chloro-4-(2,2,2-trifluoroacetamido)phenoxy]methyl}-5-methyl-1,2-oxazole-3-carboxylic acid chemical structure, C14H10ClF3N2O5, CAS 2680666-91-3
4-{[2-Chloro-4-(2,2,2-trifluoroacetamido)phenoxy]methyl}-5-methyl-1,2-oxazole-3-carboxylic acid
CAS 2680666-91-3C14H10ClF3N2O5