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Murcko scaffold

Ring system with 4 rings and 24 atoms

18 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
18
With full pages
3
Scaffold SMILES

O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

3-Methyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C20H15N3O2, CAS 331650-62-5
3-Methyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 331650-62-5C20H15N3O2
3,4-Dimethyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C21H17N3O2, CAS 380905-64-6
3,4-Dimethyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 380905-64-6C21H17N3O2
4-Methoxy-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C20H15N3O3, CAS 381715-04-4
4-Methoxy-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 381715-04-4C20H15N3O3
3,5-Dimethyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C21H17N3O2, CAS 679804-53-6
3,5-Dimethyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 679804-53-6C21H17N3O2
2-Methyl-3-nitro-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C20H14N4O4, CAS 353501-00-5
2-Methyl-3-nitro-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 353501-00-5C20H14N4O4
4-Bromo-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C19H12BrN3O2, CAS 381683-57-4
4-Bromo-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 381683-57-4C19H12BrN3O2
2,6-Dimethoxy-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C21H17N3O4, CAS 701226-27-9
2,6-Dimethoxy-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 701226-27-9C21H17N3O4
2-Iodo-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C19H12IN3O2, CAS 381209-57-0
2-Iodo-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 381209-57-0C19H12IN3O2
4-Methoxy-3-nitro-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C20H14N4O5, CAS 380887-58-1
4-Methoxy-3-nitro-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 380887-58-1C20H14N4O5
4-Ethoxy-3-nitro-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C21H16N4O5, CAS 381171-96-6
4-Ethoxy-3-nitro-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 381171-96-6C21H16N4O5
4-(2-Methylpropoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C23H21N3O3, CAS 6008-38-4
4-(2-Methylpropoxy)-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 6008-38-4C23H21N3O3
2-Nitro-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]benzamide chemical structure, C19H12N4O4, CAS 346646-63-7
2-Nitro-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]benzamide
CAS 346646-63-7C19H12N4O4
3-Butoxy-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C23H21N3O3, CAS 5757-27-7
3-Butoxy-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 5757-27-7C23H21N3O3
3,4,5-Trimethoxy-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]benzamide chemical structure, C22H19N3O5, CAS 303141-68-6
3,4,5-Trimethoxy-N-[2-(pyridin-4-yl)-1,3-benzoxazol-5-yl]benzamide
CAS 303141-68-6C22H19N3O5
2,3,5,6-Tetrafluoro-4-methoxy-N-[2-(4-pyridinyl)-1,3-benzoxazol-5-yl]benzamide chemical structure, C20H11F4N3O3, CAS 835888-85-2
2,3,5,6-Tetrafluoro-4-methoxy-N-[2-(4-pyridinyl)-1,3-benzoxazol-5-yl]benzamide
CAS 835888-85-2C20H11F4N3O3
4-Ethyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C21H17N3O2, CAS 839693-86-6
4-Ethyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 839693-86-6C21H17N3O2
2-Methoxy-3-methyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C21H17N3O3, CAS 842118-86-9
2-Methoxy-3-methyl-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 842118-86-9C21H17N3O3
5-Bromo-2-iodo-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide chemical structure, C19H11BrIN3O2, CAS 328909-23-5
5-Bromo-2-iodo-N-(2-pyridin-4-yl-1,3-benzoxazol-5-yl)benzamide
CAS 328909-23-5C19H11BrIN3O2