CompoundList
Sign in
Murcko scaffold

RefChem:382247 scaffold

55 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
55
With full pages
8
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc2c(c1)C(=O)N(c1ccccc1)C2=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the RefChem:382247 page
Murcko scaffold O=C(Nc1ccccc1)c1ccc2c(c1)C(=O)N(c1ccccc1)C2=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

RefChem:382247 chemical structure, C21H14N2O3, CAS 3348-10-5
RefChem:382247
CAS 3348-10-5C21H14N2O3
N-(4-Ethylphenyl)-1,3-dioxo-2-phenylisoindole-5-carboxamide chemical structure, C23H18N2O3, CAS 500015-55-4
N-(4-Ethylphenyl)-1,3-dioxo-2-phenylisoindole-5-carboxamide
CAS 500015-55-4C23H18N2O3
N-(2,4-Dimethoxyphenyl)-2-(2-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C24H20N2O6, CAS 519147-48-9
N-(2,4-Dimethoxyphenyl)-2-(2-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 519147-48-9C24H20N2O6
2-(4-Chlorophenyl)-N-(2,5-dimethoxyphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C23H17ClN2O5, CAS 294891-40-0
2-(4-Chlorophenyl)-N-(2,5-dimethoxyphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 294891-40-0C23H17ClN2O5
2-(2-Methoxyphenyl)-N-[2-(2-methylpropylcarbamoyl)phenyl]-1,3-dioxoisoindole-5-carboxamide chemical structure, C27H25N3O5, CAS 305361-97-1
2-(2-Methoxyphenyl)-N-[2-(2-methylpropylcarbamoyl)phenyl]-1,3-dioxoisoindole-5-carboxamide
CAS 305361-97-1C27H25N3O5
2-(3,4-Dimethylphenyl)-N-(4-hydroxyphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C23H18N2O4, CAS 311777-88-5
2-(3,4-Dimethylphenyl)-N-(4-hydroxyphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 311777-88-5C23H18N2O4
N-(4-Bromophenyl)-2-(2-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C22H15BrN2O4, CAS 314038-74-9
N-(4-Bromophenyl)-2-(2-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 314038-74-9C22H15BrN2O4
2-(2-Methoxyphenyl)-N-(4-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C23H18N2O5, CAS 330634-65-6
2-(2-Methoxyphenyl)-N-(4-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 330634-65-6C23H18N2O5
2-({[2-(4-Methoxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoic acid chemical structure, C23H16N2O6, CAS 330634-58-7
2-({[2-(4-Methoxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoic acid
CAS 330634-58-7C23H16N2O6
N-(2-Hydroxyphenyl)-2-(4-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C22H16N2O5, CAS 314038-73-8
N-(2-Hydroxyphenyl)-2-(4-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 314038-73-8C22H16N2O5
N-(4-Acetylphenyl)-2-(3,4-dimethylphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C25H20N2O4, CAS 312594-85-7
N-(4-Acetylphenyl)-2-(3,4-dimethylphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 312594-85-7C25H20N2O4
N-(2-Hydroxyphenyl)-1,3-dioxo-2-phenylisoindole-5-carboxamide chemical structure, C21H14N2O4, CAS 306320-15-0
N-(2-Hydroxyphenyl)-1,3-dioxo-2-phenylisoindole-5-carboxamide
CAS 306320-15-0C21H14N2O4
3-{[(1,3-Dioxo-2-phenyl-2,3-dihydro-1H-isoindol-5-yl)carbonyl]amino}benzoic acid chemical structure, C22H14N2O5, CAS 353467-40-0
3-{[(1,3-Dioxo-2-phenyl-2,3-dihydro-1H-isoindol-5-yl)carbonyl]amino}benzoic acid
CAS 353467-40-0C22H14N2O5
2-[({2-[4-(Ethoxycarbonyl)phenyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl}carbonyl)amino]benzoic acid chemical structure, C25H18N2O7, CAS 351424-33-4
2-[({2-[4-(Ethoxycarbonyl)phenyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl}carbonyl)amino]benzoic acid
CAS 351424-33-4C25H18N2O7
2-(2-(3-Methoxyphenyl)-1,3-dioxoisoindoline-5-carboxamido)benzoic acid chemical structure, C23H16N2O6, CAS 305360-50-3
2-(2-(3-Methoxyphenyl)-1,3-dioxoisoindoline-5-carboxamido)benzoic acid
CAS 305360-50-3C23H16N2O6
N-(2-Hydroxyphenyl)-2-(3-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C22H16N2O5, CAS 312937-85-2
N-(2-Hydroxyphenyl)-2-(3-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 312937-85-2C22H16N2O5
N-(2-Hydroxyphenyl)-2-(2-methoxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxamide chemical structure, C22H16N2O5, CAS 312594-83-5
N-(2-Hydroxyphenyl)-2-(2-methoxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindole-5-carboxamide
CAS 312594-83-5C22H16N2O5
5-{[(2-Mesityl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)carbonyl]amino}isophthalic acid chemical structure, C26H20N2O7, CAS 312317-37-6
5-{[(2-Mesityl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)carbonyl]amino}isophthalic acid
CAS 312317-37-6C26H20N2O7
5-Bromo-2-({[2-(3-methoxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoic acid chemical structure, C23H15BrN2O6, CAS 296243-89-5
5-Bromo-2-({[2-(3-methoxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoic acid
CAS 296243-89-5C23H15BrN2O6
3-({[2-(4-Methoxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoic acid chemical structure, C23H16N2O6, CAS 352217-16-4
3-({[2-(4-Methoxyphenyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoic acid
CAS 352217-16-4C23H16N2O6
N-(4-Acetamidophenyl)-2-(4-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C24H19N3O5, CAS 418780-51-5
N-(4-Acetamidophenyl)-2-(4-methoxyphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 418780-51-5C24H19N3O5
N-(4-Ethoxyphenyl)-1,3-dioxo-2-phenylisoindole-5-carboxamide chemical structure, C23H18N2O4, CAS 684227-16-5
N-(4-Ethoxyphenyl)-1,3-dioxo-2-phenylisoindole-5-carboxamide
CAS 684227-16-5C23H18N2O4
N-(4-Methoxyphenyl)-1,3-dioxo-2-phenylisoindole-5-carboxamide chemical structure, C22H16N2O4, CAS 684227-14-3
N-(4-Methoxyphenyl)-1,3-dioxo-2-phenylisoindole-5-carboxamide
CAS 684227-14-3C22H16N2O4
N-(2-Ethylphenyl)-2-(3-nitrophenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C23H17N3O5, CAS 524739-80-8
N-(2-Ethylphenyl)-2-(3-nitrophenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 524739-80-8C23H17N3O5