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Murcko scaffold

Ring system with 4 rings and 25 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
10
With full pages
4
Scaffold SMILES

O=C(Nc1[nH]c2ccccc2c(=O)c1-c1ccccc1)c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1[nH]c2ccccc2c(=O)c1-c1ccccc1)c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-(1-Methyl-4-oxo-3-phenyl-1,4-dihydroquinolin-2-yl)furan-2-carboxamide chemical structure, C21H16N2O3, CAS 883959-01-1
N-(1-Methyl-4-oxo-3-phenyl-1,4-dihydroquinolin-2-yl)furan-2-carboxamide
CAS 883959-01-1C21H16N2O3
N-(3-(2-Chlorophenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl)furan-2-carboxamide chemical structure, C21H15ClN2O3, CAS 883963-32-4
N-(3-(2-Chlorophenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl)furan-2-carboxamide
CAS 883963-32-4C21H15ClN2O3
N-(3-(2-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl)furan-2-carboxamide chemical structure, C22H18N2O4, CAS 883964-09-8
N-(3-(2-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl)furan-2-carboxamide
CAS 883964-09-8C22H18N2O4
N-[3-(4-Chlorophenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide chemical structure, C21H15ClN2O3, CAS 883962-35-4
N-[3-(4-Chlorophenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide
CAS 883962-35-4C21H15ClN2O3
N-[3-(3,4-Dimethoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide chemical structure, C23H20N2O5, CAS 883965-09-1
N-[3-(3,4-Dimethoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide
CAS 883965-09-1C23H20N2O5
N-[3-(3-Chlorophenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide chemical structure, C21H15ClN2O3, CAS 883966-53-8
N-[3-(3-Chlorophenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide
CAS 883966-53-8C21H15ClN2O3
N-[3-(3-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide chemical structure, C22H18N2O4, CAS 883965-76-2
N-[3-(3-Methoxyphenyl)-1-methyl-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide
CAS 883965-76-2C22H18N2O4
N-[1-Methyl-3-(3-methylphenyl)-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide chemical structure, C22H18N2O3, CAS 883967-08-6
N-[1-Methyl-3-(3-methylphenyl)-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide
CAS 883967-08-6C22H18N2O3
N-[1-Methyl-3-(4-methylphenyl)-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide chemical structure, C22H18N2O3, CAS 902037-29-0
N-[1-Methyl-3-(4-methylphenyl)-4-oxo-1,4-dihydroquinolin-2-yl]furan-2-carboxamide
CAS 902037-29-0C22H18N2O3
N-(1-Ethyl-3-(4-methoxyphenyl)-4-oxo-1,4-dihydroquinolin-2-yl)furan-2-carboxamide chemical structure, C23H20N2O4, CAS 879473-16-2
N-(1-Ethyl-3-(4-methoxyphenyl)-4-oxo-1,4-dihydroquinolin-2-yl)furan-2-carboxamide
CAS 879473-16-2C23H20N2O4