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Murcko scaffold

Ring system with 4 rings and 24 atoms

30 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
30
With full pages
5
Scaffold SMILES

O=c1c2ccccc2nc(C=Cc2ccco2)n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccccc2nc(C=Cc2ccco2)n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

6-Iodo-3-(2-methylphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C21H14IN3O4, CAS 429654-01-3
6-Iodo-3-(2-methylphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 429654-01-3C21H14IN3O4
3-(4-Chlorophenyl)-6-iodo-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C20H11ClIN3O4, CAS 664971-15-7
3-(4-Chlorophenyl)-6-iodo-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 664971-15-7C20H11ClIN3O4
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(3-methylphenyl)quinazolin-4-one chemical structure, C21H16N2O2, CAS 5922-10-1
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(3-methylphenyl)quinazolin-4-one
CAS 5922-10-1C21H16N2O2
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(2-methylphenyl)quinazolin-4-one chemical structure, C21H16N2O2, CAS 1772-82-3
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(2-methylphenyl)quinazolin-4-one
CAS 1772-82-3C21H16N2O2
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(2-methoxyphenyl)quinazolin-4-one chemical structure, C21H16N2O3, CAS 337496-88-5
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(2-methoxyphenyl)quinazolin-4-one
CAS 337496-88-5C21H16N2O3
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(3-methoxyphenyl)quinazolin-4-one chemical structure, C21H16N2O3, CAS 337496-90-9
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(3-methoxyphenyl)quinazolin-4-one
CAS 337496-90-9C21H16N2O3
2-[(E)-2-(Furan-2-yl)ethenyl]-3-phenylquinazolin-4-one chemical structure, C20H14N2O2, CAS 71822-45-2
2-[(E)-2-(Furan-2-yl)ethenyl]-3-phenylquinazolin-4-one
CAS 71822-45-2C20H14N2O2
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(4-methylphenyl)quinazolin-4-one chemical structure, C21H16N2O2, CAS 116990-38-6
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(4-methylphenyl)quinazolin-4-one
CAS 116990-38-6C21H16N2O2
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(3-hydroxyphenyl)quinazolin-4-one chemical structure, C20H14N2O3, CAS 1624273-50-2
2-[(E)-2-(Furan-2-yl)ethenyl]-3-(3-hydroxyphenyl)quinazolin-4-one
CAS 1624273-50-2C20H14N2O3
2-[(E)-2-(Furan-2-yl)ethenyl]-6-iodo-3-(3-methylphenyl)quinazolin-4-one chemical structure, C21H15IN2O2, CAS 425401-82-7
2-[(E)-2-(Furan-2-yl)ethenyl]-6-iodo-3-(3-methylphenyl)quinazolin-4-one
CAS 425401-82-7C21H15IN2O2
2-[(E)-2-(Furan-2-yl)ethenyl]-6-iodo-3-phenylquinazolin-4(3H)-one chemical structure, C20H13IN2O2, CAS 361988-78-5
2-[(E)-2-(Furan-2-yl)ethenyl]-6-iodo-3-phenylquinazolin-4(3H)-one
CAS 361988-78-5C20H13IN2O2
2-[(E)-2-(Furan-2-yl)ethenyl]-6-iodo-3-(2-methylphenyl)quinazolin-4-one chemical structure, C21H15IN2O2, CAS 361185-52-6
2-[(E)-2-(Furan-2-yl)ethenyl]-6-iodo-3-(2-methylphenyl)quinazolin-4-one
CAS 361185-52-6C21H15IN2O2
3-(2-Methylphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C21H15N3O4, CAS 17558-31-5
3-(2-Methylphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 17558-31-5C21H15N3O4
6-Iodo-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]-3-phenylquinazolin-4-one chemical structure, C20H12IN3O4, CAS 429643-71-0
6-Iodo-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]-3-phenylquinazolin-4-one
CAS 429643-71-0C20H12IN3O4
3-(4-Methylphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C21H15N3O4, CAS 213686-84-1
3-(4-Methylphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 213686-84-1C21H15N3O4
3-(2,6-Dichlorophenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C20H11Cl2N3O4, CAS 384375-51-3
3-(2,6-Dichlorophenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 384375-51-3C20H11Cl2N3O4
3-(3-Methoxyphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C21H15N3O5, CAS 385392-25-6
3-(3-Methoxyphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 385392-25-6C21H15N3O5
3-(4-Hydroxyphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C20H13N3O5, CAS 384798-90-7
3-(4-Hydroxyphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 384798-90-7C20H13N3O5
3-(4-Bromophenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C20H12BrN3O4, CAS 213686-79-4
3-(4-Bromophenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 213686-79-4C20H12BrN3O4
2-[(E)-2-(5-Nitrofuran-2-yl)ethenyl]-3-phenylquinazolin-4-one chemical structure, C20H13N3O4, CAS 17558-30-4
2-[(E)-2-(5-Nitrofuran-2-yl)ethenyl]-3-phenylquinazolin-4-one
CAS 17558-30-4C20H13N3O4
3-(3-Methylphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C21H15N3O4, CAS 1164464-01-0
3-(3-Methylphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 1164464-01-0C21H15N3O4
3-(2-Chlorophenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C20H12ClN3O4, CAS 385391-71-9
3-(2-Chlorophenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 385391-71-9C20H12ClN3O4
3-(4-Methoxyphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C21H15N3O5, CAS 430442-11-8
3-(4-Methoxyphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 430442-11-8C21H15N3O5
3-(2-Methoxyphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one chemical structure, C21H15N3O5, CAS 213687-01-5
3-(2-Methoxyphenyl)-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one
CAS 213687-01-5C21H15N3O5