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Murcko scaffold

Ring system with 2 rings and 15 atoms

18 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
18
With full pages
5
Scaffold SMILES

O=C1C=CCC(C=Cc2ccccc2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CCC(C=Cc2ccccc2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

5,6-Dihydro-4-methoxy-6-(2-phenylethenyl)-2H-pyran-2-one chemical structure, C14H14O3, CAS 1635-33-2
5,6-Dihydro-4-methoxy-6-(2-phenylethenyl)-2H-pyran-2-one
CAS 1635-33-2C14H14O3
(+)-Kavain chemical structure, C14H14O3, CAS 500-64-1
(+)-Kavain
CAS 500-64-1C14H14O3
4-Methoxy-2-[(E)-2-(3-methoxyphenyl)ethenyl]-2,3-dihydropyran-6-one chemical structure, C15H16O4, CAS 62378-74-9
4-Methoxy-2-[(E)-2-(3-methoxyphenyl)ethenyl]-2,3-dihydropyran-6-one
CAS 62378-74-9C15H16O4
(±)-Kawain chemical structure, C14H14O3, CAS 3155-48-4
(±)-Kawain
CAS 3155-48-4C14H14O3
Goniothalamin chemical structure, C13H12O2, CAS 17303-67-2
Goniothalamin
CAS 17303-67-2C13H12O2
[(2S,3S)-2,4-Dimethoxy-6-oxo-2-[(E)-2-phenylethenyl]-3H-pyran-3-yl] acetate chemical structure, C17H18O6, CAS 60037-33-4
[(2S,3S)-2,4-Dimethoxy-6-oxo-2-[(E)-2-phenylethenyl]-3H-pyran-3-yl] acetate
CAS 60037-33-4C17H18O6
Kavaform chemical structure, C24H20MgN4O11, CAS 8074-25-7
Kavaform
CAS 8074-25-7C24H20MgN4O11
2H-Pyran-2-one, 5,6-dihydro-6-[(1E)-2-phenylethenyl]-, (6S)- chemical structure, C13H12O2, CAS 122046-62-2
2H-Pyran-2-one, 5,6-dihydro-6-[(1E)-2-phenylethenyl]-, (6S)-
CAS 122046-62-2C13H12O2
5,6-Dihydroyangonin chemical structure, C15H16O4, CAS 3328-60-7
5,6-Dihydroyangonin
CAS 3328-60-7C15H16O4
(-)-Kawain chemical structure, C14H14O3, CAS 188643-55-2
(-)-Kawain
CAS 188643-55-2C14H14O3
(5S,6S)-5,6-Dihydro-5-hydroxy-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one chemical structure, C14H14O4, CAS 52247-80-0
(5S,6S)-5,6-Dihydro-5-hydroxy-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one
CAS 52247-80-0C14H14O4
4-Methyl-6-(2-phenylethenyl)-5,6-dihydro-2H-pyran-2-one chemical structure, C14H14O2, CAS 134641-64-8
4-Methyl-6-(2-phenylethenyl)-5,6-dihydro-2H-pyran-2-one
CAS 134641-64-8C14H14O2
4-Hydroxy-6-(2-phenylethenyl)-5,6-dihydro-2H-pyran-2-one chemical structure, C13H12O3, CAS 62378-62-5
4-Hydroxy-6-(2-phenylethenyl)-5,6-dihydro-2H-pyran-2-one
CAS 62378-62-5C13H12O3
(6S)-6-[2-(4-Fluorophenyl)ethenyl]-5,6-dihydro-2H-pyran-2-one chemical structure, C13H11FO2, CAS 873316-13-3
(6S)-6-[2-(4-Fluorophenyl)ethenyl]-5,6-dihydro-2H-pyran-2-one
CAS 873316-13-3C13H11FO2
(6S)-6-[2-(4-Nitrophenyl)ethenyl]-5,6-dihydro-2H-pyran-2-one chemical structure, C13H11NO4, CAS 873316-12-2
(6S)-6-[2-(4-Nitrophenyl)ethenyl]-5,6-dihydro-2H-pyran-2-one
CAS 873316-12-2C13H11NO4
4'-Hydroxy rac-Kavain chemical structure, C14H14O4, CAS 1401441-87-9
4'-Hydroxy rac-Kavain
CAS 1401441-87-9C14H14O4
(5R,6s)-5,6-Dihydro-5-hydroxy-4-methoxy-6-[(e)-2-phenylethenyl]-2H-pyran-2-one chemical structure, C14H14O4, CAS 52247-79-7
(5R,6s)-5,6-Dihydro-5-hydroxy-4-methoxy-6-[(e)-2-phenylethenyl]-2H-pyran-2-one
CAS 52247-79-7C14H14O4
4-Hydroxy-2-[(E)-2-(4-methoxyphenyl)ethenyl]-2,3-dihydropyran-6-one chemical structure, C14H14O4, CAS 62378-65-8
4-Hydroxy-2-[(E)-2-(4-methoxyphenyl)ethenyl]-2,3-dihydropyran-6-one
CAS 62378-65-8C14H14O4