Murcko scaffold
9-Benzylidenefluorene scaffold
85 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 20
- Chemicals
- 85
- With full pages
- 12
Scaffold SMILES
C(=C1c2ccccc2-c2ccccc21)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 85 of 85 chemicals
N,O-Diacetyl-N-(9-(p-methoxybenzylidene)fluoren-3-yl)hydroxylamine
CAS 101976-65-2C25H21NO4
Artemether, lumefantrine drug combination
CAS 141204-94-6C46H58Cl3NO6
![2-[(E)-(2-Nitrofluoren-9-ylidene)methyl]phenol chemical structure, C20H13NO3](/s/PEYKRJBXACUOOB-WOJGMQOQSA-N.svg)
2-[(E)-(2-Nitrofluoren-9-ylidene)methyl]phenol
C20H13NO3
Desbutyllumefantrine
CAS 355841-11-1C26H24Cl3NO
Artemether, lumefantrine
C46H58Cl3NO6
Orb3174312
C46H58Cl3NO6
2,7-Dinitro-9-(phenylmethylene)-9H-fluorene
CAS 65550-83-6C20H12N2O4
![9-[(3-Chlorophenyl)methylidene]-9H-fluorene chemical structure, C20H13Cl, CAS 23000-25-1](/s/BALOVKADFGKBCH-UHFFFAOYSA-N.svg)
9-[(3-Chlorophenyl)methylidene]-9H-fluorene
CAS 23000-25-1C20H13Cl
2,7-Dichloro-9-(4-chlorobenzylidene)-9H-fluorene
CAS 4364-35-6C20H11Cl3
![2,7-Dichloro-9-[(3-nitrophenyl)methylidene]-9H-fluorene chemical structure, C20H11Cl2NO2, CAS 4364-36-7](/s/QOWHFCIEVDAKCI-UHFFFAOYSA-N.svg)
2,7-Dichloro-9-[(3-nitrophenyl)methylidene]-9H-fluorene
CAS 4364-36-7C20H11Cl2NO2
![2,4,5,7-Tetranitro-9-{[4-(prop-2-EN-1-yl)phenyl]methylidene}-9H-fluorene chemical structure, C23H14N4O8, CAS 95454-51-6](/s/OKQBQCBZUMBSQR-UHFFFAOYSA-N.svg)
2,4,5,7-Tetranitro-9-{[4-(prop-2-EN-1-yl)phenyl]methylidene}-9H-fluorene
CAS 95454-51-6C23H14N4O8
9-(1-Phenylethylidene)-9H-fluorene
CAS 61370-30-7C21H16
![N,N-Diethyl-4-[(9H-fluoren-9-ylidene)methyl]aniline chemical structure, C24H23N, CAS 88695-22-1](/s/KYQAVIAZLHNYJK-UHFFFAOYSA-N.svg)
N,N-Diethyl-4-[(9H-fluoren-9-ylidene)methyl]aniline
CAS 88695-22-1C24H23N
9-(4-Chlorobenzylidene)-2-nitro-9H-fluorene
C20H12ClNO2
![(9Z)-2-Nitro-9-[(4-nitrophenyl)methylidene]fluorene chemical structure, C20H12N2O4, CAS 30084-68-5](/s/NKGMHUXCLKRPBF-ODLFYWEKSA-N.svg)
(9Z)-2-Nitro-9-[(4-nitrophenyl)methylidene]fluorene
CAS 30084-68-5C20H12N2O4
![9-[(2-Chloro-5-methylphenyl)methylene]-9H-fluorene chemical structure, C21H15Cl, CAS 150012-28-5](/s/XPTZBENVKIWDGR-UHFFFAOYSA-N.svg)
9-[(2-Chloro-5-methylphenyl)methylene]-9H-fluorene
CAS 150012-28-5C21H15Cl
![2-(Butylamino)-1-{(9E)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]-9H-fluoren-4-yl}ethan-1-ol chemical structure, C26H24Cl3NO, CAS 252990-19-5](/s/YLBUTQNEBVPTES-SRZZPIQSSA-N.svg)
2-(Butylamino)-1-{(9E)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]-9H-fluoren-4-yl}ethan-1-ol
CAS 252990-19-5C26H24Cl3NO
Lumefantrine-d18
CAS 1185240-53-2C30H32Cl3NO
![2,7-Dibromo-9-{[4-(dodecyloxy)phenyl]methylidene}-9H-fluorene chemical structure, C32H36Br2O, CAS 848391-89-9](/s/SRFNCMHBMGXVHG-UHFFFAOYSA-N.svg)
2,7-Dibromo-9-{[4-(dodecyloxy)phenyl]methylidene}-9H-fluorene
CAS 848391-89-9C32H36Br2O
![2-(Dibutylamino)-2-[2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol chemical structure, C30H32Cl3NO, CAS 2170653-95-7](/s/AGQOFEQBDUCCRH-UHFFFAOYSA-N.svg)
2-(Dibutylamino)-2-[2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol
CAS 2170653-95-7C30H32Cl3NO
Lumefantrine impurity 2
C26H24Cl3NO
![9-[(2-Methoxyphenyl)methylidene]-2-nitro-9H-fluorene chemical structure, C21H15NO3, CAS 190071-19-3](/s/LIVLGIRFBZKJEV-UHFFFAOYSA-N.svg)
9-[(2-Methoxyphenyl)methylidene]-2-nitro-9H-fluorene
CAS 190071-19-3C21H15NO3
![2-[2-[(E)-(2-Nitrofluoren-9-ylidene)methyl]phenoxy]ethanamine chemical structure, C22H18N2O3, CAS 1425944-22-4](/s/BJIFXXDQMBHYKG-DEDYPNTBSA-N.svg)
2-[2-[(E)-(2-Nitrofluoren-9-ylidene)methyl]phenoxy]ethanamine
CAS 1425944-22-4C22H18N2O3
Ylidene)methyl)phenoxy)ethan-1-amine
C22H18N2O3
- Desbutyl lumefantrine D91346606-35-6C26H24Cl3NO
- 2-(Dibutylamino)-2-(2,7-dichloro-9-(4-chlorobenzylidene)-9H-fluoren-4-yl)ethanol, (RS, Z)-1331642-68-2C30H32Cl3NO
- 4-[(9H-Fluoren-9-ylidene)methyl]-N,N,3-trimethylaniline88740-79-8C23H21N
- 9-[(2-Chlorophenyl)methylidene]-1-fluoro-9H-fluorene89883-25-0C20H12ClF
- 9-[(2-Chloro-6-fluorophenyl)methylidene]-9H-fluorene89883-26-1C20H12ClF
- 9-[(2-Chloro-4-fluorophenyl)methylidene]-9H-fluorene89883-27-2C20H12ClF
- 9-[Iodo(phenyl)methylidene]-9H-fluorene87682-46-0C20H13I
- 9-Benzylidene-1-methyl-9H-fluorene58243-50-8C21H16
- 2-(Dibutylamino)-1-[2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol, 10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecaneC46H58Cl3NO6
- Lumefantrine-d92477594-24-2C30H32Cl3NO
- 9-[[4-(2-Chloroethoxy)phenyl]methylene]-9H-fluorene106303-47-3C22H17ClO
- 2-(Dibutylamino)-1-[(9E)-2,7-dichloro-9-[(4-chlorophenyl)methylidene]fluoren-4-yl]ethanol, 10-methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecaneC46H58Cl3NO6
- 1-(RS)-2-(Dibutylamino)-2-[2,7-dichloro-9-(4-chlorobenxylidene)]-9H-fluoren-4-yl]ethanol-E/Z mixtureC30H32Cl3NO
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(N=C2c3ccccc3-c3ccccc32)cc18 chemicals
c1ccc(Cn2c3c(c4ccccc42)CNCC3)cc15 chemicals
c1ccc(Cn2c3ccccc3c3ccccc32)cc14 chemicals
c1ccc(Cn2c3ccccc3c3nncnc32)cc13 chemicals![Scaffold O=c1[nH]ncc2c3ccccc3n(Cc3ccccc3)c12](/scaffold/BXZMDFCSGHUUQF-UHFFFAOYSA-N/structure.svg)
O=c1[nH]ncc2c3ccccc3n(Cc3ccccc3)c122 chemicals
c1ccc(Cn2c3c(c4ccccc42)CCCC3)cc12 chemicals
c1ccc2c(c1)c1ccccc1n2CN1CCOCC12 chemicals
O=C(c1ccccc1)n1c2c(c3ccccc31)CCCC22 chemicals
C(=C1c2ccccc2-c2ccccc21)c1ccccn12 chemicals
c1ccc(CN2c3ccccc3C3CCCCC32)cc11 chemical
O=C(c1ccccc1)n1c2ccccc2c2ccccc211 chemical![Scaffold S=c1nc2c(n[nH]1)c1ccccc1n2Cc1ccccc1](/scaffold/CMWAFGJNLNZSMR-UHFFFAOYSA-N/structure.svg)
S=c1nc2c(n[nH]1)c1ccccc1n2Cc1ccccc11 chemical