CompoundList
Sign in
Murcko scaffold

Tetrahydro-1,4-benzodiazepin-2-one scaffold

84 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
84
With full pages
5
Scaffold SMILES

O=C1CNCc2ccccc2N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Tetrahydro-1,4-benzodiazepin-2-one page
Murcko scaffold O=C1CNCc2ccccc2N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 84 chemicals

Tetrahydro-1,4-benzodiazepin-2-one chemical structure, C9H10N2O, CAS 1824-72-2
Tetrahydro-1,4-benzodiazepin-2-one
CAS 1824-72-2C9H10N2O
7-Chloro-3-methyl-4-propyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one chemical structure, C13H17ClN2O, CAS 162931-18-2
7-Chloro-3-methyl-4-propyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one
CAS 162931-18-2C13H17ClN2O
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3,4,5-tetrahydro-4-(3-methyl-2-butenyl)- chemical structure, C14H17ClN2O, CAS 258849-78-4
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3,4,5-tetrahydro-4-(3-methyl-2-butenyl)-
CAS 258849-78-4C14H17ClN2O
7-Chloro-3-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one chemical structure, C15H19ClN2O, CAS 258849-79-5
7-Chloro-3-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one
CAS 258849-79-5C15H19ClN2O
7-Chloro-4-(3-ethyl-pent-2-enyl)-3-methyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one chemical structure, C17H23ClN2O, CAS 258849-80-8
7-Chloro-4-(3-ethyl-pent-2-enyl)-3-methyl-1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one
CAS 258849-80-8C17H23ClN2O
6-Chloro-3-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C15H19ClN2O, CAS 258849-81-9
6-Chloro-3-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258849-81-9C15H19ClN2O
6-Chloro-4-(3-ethyl-pent-2-enyl)-3-methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C17H23ClN2O, CAS 258849-82-0
6-Chloro-4-(3-ethyl-pent-2-enyl)-3-methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258849-82-0C17H23ClN2O
3-Methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C15H20N2O, CAS 258849-83-1
3-Methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258849-83-1C15H20N2O
(S)-7-Chloro-3-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C15H19ClN2O, CAS 258849-87-5
(S)-7-Chloro-3-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258849-87-5C15H19ClN2O
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3,4,5-tetrahydro-3-methyl-4-(2-methyl-2-propenyl)-, (3S)- chemical structure, C14H17ClN2O, CAS 258849-89-7
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3,4,5-tetrahydro-3-methyl-4-(2-methyl-2-propenyl)-, (3S)-
CAS 258849-89-7C14H17ClN2O
4H-1,4-Benzodiazepine-4-acetamide, 7-chloro-1,2,3,5-tetrahydro-3-methyl-2-oxo-, (3S)- chemical structure, C12H14ClN3O2, CAS 258849-93-3
4H-1,4-Benzodiazepine-4-acetamide, 7-chloro-1,2,3,5-tetrahydro-3-methyl-2-oxo-, (3S)-
CAS 258849-93-3C12H14ClN3O2
4H-1,4-Benzodiazepine-4-carboxamide, 7-chloro-1,2,3,5-tetrahydro-N,3-dimethyl-2-oxo-, (3S)- chemical structure, C12H14ClN3O2, CAS 258849-94-4
4H-1,4-Benzodiazepine-4-carboxamide, 7-chloro-1,2,3,5-tetrahydro-N,3-dimethyl-2-oxo-, (3S)-
CAS 258849-94-4C12H14ClN3O2
(S)-7-Chloro-3-methyl-2-oxo-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylic acid isopropylamide chemical structure, C14H18ClN3O2, CAS 258849-95-5
(S)-7-Chloro-3-methyl-2-oxo-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylic acid isopropylamide
CAS 258849-95-5C14H18ClN3O2
7-Chloro-3-isopropyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C17H23ClN2O, CAS 258849-96-6
7-Chloro-3-isopropyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258849-96-6C17H23ClN2O
7-Chloro-3-isopropyl-2-oxo-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylic acid tert-butyl ester chemical structure, C17H23ClN2O3, CAS 258849-99-9
7-Chloro-3-isopropyl-2-oxo-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylic acid tert-butyl ester
CAS 258849-99-9C17H23ClN2O3
7-Chloro-3-isopropyl-1-methyl-2-oxo-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylic acid tert-butyl ester chemical structure, C18H25ClN2O3, CAS 258850-03-2
7-Chloro-3-isopropyl-1-methyl-2-oxo-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxylic acid tert-butyl ester
CAS 258850-03-2C18H25ClN2O3
7-Chloro-3-isopropyl-1-methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C13H17ClN2O, CAS 258850-04-3
7-Chloro-3-isopropyl-1-methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258850-04-3C13H17ClN2O
7-Chloro-3-isopropyl-1-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C18H25ClN2O, CAS 258850-05-4
7-Chloro-3-isopropyl-1-methyl-4-(3-methyl-but-2-enyl)-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258850-05-4C18H25ClN2O
3-Methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C10H12N2O, CAS 258850-07-6
3-Methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258850-07-6C10H12N2O
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3,4,5-tetrahydro- chemical structure, C9H9ClN2O, CAS 258850-08-7
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3,4,5-tetrahydro-
CAS 258850-08-7C9H9ClN2O
7-Chloro-3-methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C10H11ClN2O, CAS 162931-17-1
7-Chloro-3-methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 162931-17-1C10H11ClN2O
(3S)-7-Chloro-3-methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C10H11ClN2O, CAS 258850-09-8
(3S)-7-Chloro-3-methyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258850-09-8C10H11ClN2O
7-Chloro-3-isopropyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one chemical structure, C12H15ClN2O, CAS 258850-11-2
7-Chloro-3-isopropyl-1,3,4,5-tetrahydro-1,4-benzodiazepin-2-one
CAS 258850-11-2C12H15ClN2O
O4-tert-butyl O8-methyl 2-oxo-3,5-dihydro-1H-1,4-benzodiazepine-4,8-dicarboxylate chemical structure, C16H20N2O5, CAS 637338-10-4
O4-tert-butyl O8-methyl 2-oxo-3,5-dihydro-1H-1,4-benzodiazepine-4,8-dicarboxylate
CAS 637338-10-4C16H20N2O5