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Murcko scaffold

Ring system with 3 rings and 38 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
38
Chemicals
7
With full pages
1
Scaffold SMILES

O=C(CNC(=O)CNC(=O)OCc1ccccc1)NCC(=O)NCC(=O)Nc1ccc2ccc(=O)oc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)CNC(=O)OCc1ccccc1)NCC(=O)NCC(=O)Nc1ccc2ccc(=O)oc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Z-Devd-afc chemical structure, C36H38F3N5O14, CAS 1135416-11-3
Z-Devd-afc
CAS 1135416-11-3C36H38F3N5O14
Z-Val-Glu-Ile-Asp-AFC chemical structure, C38H44F3N5O12, CAS 219138-06-4
Z-Val-Glu-Ile-Asp-AFC
CAS 219138-06-4C38H44F3N5O12
Z-Ietd-afc chemical structure, C37H42F3N5O13, CAS 219138-02-0
Z-Ietd-afc
CAS 219138-02-0C37H42F3N5O13
Z-Leu-Arg-Gly-Gly-AMC chemical structure, C34H44N8O8, CAS 167698-68-2
Z-Leu-Arg-Gly-Gly-AMC
CAS 167698-68-2C34H44N8O8
Z-Asp-Gln-Met-Asp-AFC chemical structure, C36H39F3N6O13S, CAS 1926163-45-2
Z-Asp-Gln-Met-Asp-AFC
CAS 1926163-45-2C36H39F3N6O13S
Z-Leu-Arg-Gly-Gly-AMC Acetate chemical structure, C36H48N8O10
Z-Leu-Arg-Gly-Gly-AMC Acetate
C36H48N8O10
Z-LRGG-AMC (trifluoroacetate salt) chemical structure, C36H45F3N8O10
Z-LRGG-AMC (trifluoroacetate salt)
C36H45F3N8O10