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Murcko scaffold

6-(Piperidin-1-yl)-3,4-dihydropyrimidin-4-one scaffold

37 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
37
With full pages
3
Scaffold SMILES

O=c1cc(N2CCCCC2)nc[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-(Piperidin-1-yl)-3,4-dihydropyrimidin-4-one page
Murcko scaffold O=c1cc(N2CCCCC2)nc[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

3-Methyl-6-(4-(trifluoromethyl)piperidin-1-yl)pyrimidin-4(3H)-one chemical structure, C11H14F3N3O, CAS 2320177-29-3
3-Methyl-6-(4-(trifluoromethyl)piperidin-1-yl)pyrimidin-4(3H)-one
CAS 2320177-29-3C11H14F3N3O
2-Amino-6-(4-aminopiperidin-1-yl)pyrimidin-4(3H)-one dihydrochloride chemical structure, C9H17Cl2N5O, CAS 1158247-58-5
2-Amino-6-(4-aminopiperidin-1-yl)pyrimidin-4(3H)-one dihydrochloride
CAS 1158247-58-5C9H17Cl2N5O
2-Amino-6-[3-(hydroxymethyl)piperidin-1-yl]pyrimidin-4(3H)-one chemical structure, C10H16N4O2, CAS 1199215-84-3
2-Amino-6-[3-(hydroxymethyl)piperidin-1-yl]pyrimidin-4(3H)-one
CAS 1199215-84-3C10H16N4O2
2-Amino-6-(3-aminopiperidin-1-yl)pyrimidin-4(3H)-one dihydrochloride chemical structure, C9H17Cl2N5O, CAS 1332529-86-8
2-Amino-6-(3-aminopiperidin-1-yl)pyrimidin-4(3H)-one dihydrochloride
CAS 1332529-86-8C9H17Cl2N5O
4-Hydroxy-6-(3-hydroxypiperidin-1-yl)pyrimidine chemical structure, C9H13N3O2, CAS 1159816-52-0
4-Hydroxy-6-(3-hydroxypiperidin-1-yl)pyrimidine
CAS 1159816-52-0C9H13N3O2
1-(6-Oxo-1,6-dihydropyrimidin-4-yl)piperidine-4-carboxylic acid chemical structure, C10H13N3O3, CAS 1596926-46-3
1-(6-Oxo-1,6-dihydropyrimidin-4-yl)piperidine-4-carboxylic acid
CAS 1596926-46-3C10H13N3O3
4-Hydroxy-2-methyl-6-(3-methylpiperidin-1-yl)pyrimidine chemical structure, C11H17N3O, CAS 1412961-22-8
4-Hydroxy-2-methyl-6-(3-methylpiperidin-1-yl)pyrimidine
CAS 1412961-22-8C11H17N3O
4-Hydroxy-2-methyl-6-(4-methylpiperidin-1-yl)pyrimidine chemical structure, C11H17N3O, CAS 1412954-51-8
4-Hydroxy-2-methyl-6-(4-methylpiperidin-1-yl)pyrimidine
CAS 1412954-51-8C11H17N3O
6-[3-(Hydroxymethyl)piperidin-1-yl]-3,4-dihydropyrimidin-4-one chemical structure, C10H15N3O2, CAS 1593816-62-6
6-[3-(Hydroxymethyl)piperidin-1-yl]-3,4-dihydropyrimidin-4-one
CAS 1593816-62-6C10H15N3O2
6-[4-(Hydroxymethyl)piperidin-1-yl]-3,4-dihydropyrimidin-4-one chemical structure, C10H15N3O2, CAS 1603127-91-8
6-[4-(Hydroxymethyl)piperidin-1-yl]-3,4-dihydropyrimidin-4-one
CAS 1603127-91-8C10H15N3O2
6-(4-Hydroxypiperidin-1-yl)-3,4-dihydropyrimidin-4-one chemical structure, C9H13N3O2, CAS 1597210-45-1
6-(4-Hydroxypiperidin-1-yl)-3,4-dihydropyrimidin-4-one
CAS 1597210-45-1C9H13N3O2
6-(Piperidin-1-yl)-3,4-dihydropyrimidin-4-one chemical structure, C9H13N3O, CAS 19808-29-8
6-(Piperidin-1-yl)-3,4-dihydropyrimidin-4-one
CAS 19808-29-8C9H13N3O
6-(4-Aminopiperidin-1-yl)-2-methylpyrimidin-4(1H)-one chemical structure, C10H16N4O, CAS 1594520-82-7
6-(4-Aminopiperidin-1-yl)-2-methylpyrimidin-4(1H)-one
CAS 1594520-82-7C10H16N4O
6-(4-Aminopiperidin-1-yl)-3,4-dihydropyrimidin-4-one chemical structure, C9H14N4O, CAS 1592610-66-6
6-(4-Aminopiperidin-1-yl)-3,4-dihydropyrimidin-4-one
CAS 1592610-66-6C9H14N4O
6-(3-Aminopiperidin-1-yl)-3,4-dihydropyrimidin-4-one chemical structure, C9H14N4O, CAS 1592590-71-0
6-(3-Aminopiperidin-1-yl)-3,4-dihydropyrimidin-4-one
CAS 1592590-71-0C9H14N4O
1-(6-Oxo-1,6-dihydropyrimidin-4-yl)piperidine-3-carboxylic acid chemical structure, C10H13N3O3, CAS 1603098-08-3
1-(6-Oxo-1,6-dihydropyrimidin-4-yl)piperidine-3-carboxylic acid
CAS 1603098-08-3C10H13N3O3
Ethyl 1-(6-oxo-1,6-dihydropyrimidin-4-yl)piperidine-4-carboxylate chemical structure, C12H17N3O3, CAS 1711684-81-9
Ethyl 1-(6-oxo-1,6-dihydropyrimidin-4-yl)piperidine-4-carboxylate
CAS 1711684-81-9C12H17N3O3
4-Hydroxy-2-methyl-6-(piperidin-1-yl)pyrimidine chemical structure, C10H15N3O, CAS 874495-86-0
4-Hydroxy-2-methyl-6-(piperidin-1-yl)pyrimidine
CAS 874495-86-0C10H15N3O
Ethyl 1-(6-oxo-1,6-dihydropyrimidin-4-yl)piperidine-3-carboxylate chemical structure, C12H17N3O3, CAS 1777522-70-9
Ethyl 1-(6-oxo-1,6-dihydropyrimidin-4-yl)piperidine-3-carboxylate
CAS 1777522-70-9C12H17N3O3
Methyl 1-(6-oxo-1,6-dihydropyrimidin-4-yl)piperidine-4-carboxylate chemical structure, C11H15N3O3, CAS 1777522-82-3
Methyl 1-(6-oxo-1,6-dihydropyrimidin-4-yl)piperidine-4-carboxylate
CAS 1777522-82-3C11H15N3O3
Methyl 1-(6-oxo-1,6-dihydropyrimidin-4-yl)piperidine-3-carboxylate chemical structure, C11H15N3O3, CAS 1770219-80-1
Methyl 1-(6-oxo-1,6-dihydropyrimidin-4-yl)piperidine-3-carboxylate
CAS 1770219-80-1C11H15N3O3
4-Hydroxy-2-(iso-propyl)-6-(piperidin-1-yl)-pyrimidine chemical structure, C12H19N3O, CAS 1412960-84-9
4-Hydroxy-2-(iso-propyl)-6-(piperidin-1-yl)-pyrimidine
CAS 1412960-84-9C12H19N3O
4-Hydroxy-2-(iso-propyl)-6-(3-methylpiperidin-1-yl)pyrimidine chemical structure, C13H21N3O, CAS 1412954-00-7
4-Hydroxy-2-(iso-propyl)-6-(3-methylpiperidin-1-yl)pyrimidine
CAS 1412954-00-7C13H21N3O
4-Hydroxy-2-(iso-propyl)-6-(4-methylpiperidin-1-yl)pyrimidine chemical structure, C13H21N3O, CAS 1412956-73-0
4-Hydroxy-2-(iso-propyl)-6-(4-methylpiperidin-1-yl)pyrimidine
CAS 1412956-73-0C13H21N3O