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Murcko scaffold

Ring system with 4 rings and 25 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(C1CCCCC1)N(Cc1cccnc1)c1nc2ccccc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C1CCCCC1)N(Cc1cccnc1)c1nc2ccccc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N-(6-Fluoro-1,3-benzothiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C20H20FN3OS, CAS 895019-14-4
N-(6-Fluoro-1,3-benzothiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895019-14-4C20H20FN3OS
N-(6-Chloro-1,3-benzothiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C20H20ClN3OS, CAS 895022-87-4
N-(6-Chloro-1,3-benzothiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895022-87-4C20H20ClN3OS
N-(4-Ethoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C22H25N3O2S, CAS 895008-42-1
N-(4-Ethoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895008-42-1C22H25N3O2S
N-(4-Fluorobenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C20H20FN3OS, CAS 895012-50-7
N-(4-Fluorobenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895012-50-7C20H20FN3OS
N-(5-Methoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C21H23N3O2S, CAS 895413-29-3
N-(5-Methoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895413-29-3C21H23N3O2S
N-(6-Methylbenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C21H23N3OS, CAS 895007-30-4
N-(6-Methylbenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895007-30-4C21H23N3OS
N-(6-Methoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C21H23N3O2S, CAS 895011-41-3
N-(6-Methoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895011-41-3C21H23N3O2S
N-(4-Methoxy-7-methylbenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C22H25N3O2S, CAS 895426-94-5
N-(4-Methoxy-7-methylbenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895426-94-5C22H25N3O2S
N-(6-Ethoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C22H25N3O2S, CAS 895015-30-2
N-(6-Ethoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895015-30-2C22H25N3O2S
N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C20H19F2N3OS, CAS 895436-22-3
N-(4,6-Difluorobenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895436-22-3C20H19F2N3OS
N-(4-Methylbenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C21H23N3OS, CAS 894999-28-1
N-(4-Methylbenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 894999-28-1C21H23N3OS
N-(4-Methoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C21H23N3O2S, CAS 895004-07-6
N-(4-Methoxybenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895004-07-6C21H23N3O2S
N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide chemical structure, C20H20ClN3OS, CAS 895016-28-1
N-(4-Chlorobenzo[d]thiazol-2-yl)-N-(pyridin-3-ylmethyl)cyclohexanecarboxamide
CAS 895016-28-1C20H20ClN3OS
N-(4,5-Dimethyl-1,3-benzothiazol-2-yl)-N-[(pyridin-3-yl)methyl]cyclohexanecarboxamide chemical structure, C22H25N3OS, CAS 895417-36-4
N-(4,5-Dimethyl-1,3-benzothiazol-2-yl)-N-[(pyridin-3-yl)methyl]cyclohexanecarboxamide
CAS 895417-36-4C22H25N3OS