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Murcko scaffold

4-(Pyridin-3-yl)thiazole scaffold

108 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
108
With full pages
8
Scaffold SMILES

c1cncc(-c2cscn2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyridin-3-yl)thiazole page
Murcko scaffold c1cncc(-c2cscn2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 108 chemicals

4-(3-Pyridinyl)-2-thiazolamine chemical structure, C8H7N3S, CAS 30235-27-9
4-(3-Pyridinyl)-2-thiazolamine
CAS 30235-27-9C8H7N3S
2-Methyl-4-(3-pyridyl)thiazole chemical structure, C9H8N2S, CAS 122845-35-6
2-Methyl-4-(3-pyridyl)thiazole
CAS 122845-35-6C9H8N2S
Methyl 2-amino-4-(3-pyridinyl)-1,3-thiazole-5-carboxylate chemical structure, C10H9N3O2S, CAS 400086-46-6
Methyl 2-amino-4-(3-pyridinyl)-1,3-thiazole-5-carboxylate
CAS 400086-46-6C10H9N3O2S
N-(4-(Pyridin-3-yl)thiazol-2-yl)acetamide chemical structure, C10H9N3OS, CAS 118371-30-5
N-(4-(Pyridin-3-yl)thiazol-2-yl)acetamide
CAS 118371-30-5C10H9N3OS
2-Chloro-6-methyl-5-(2-methyl-1,3-thiazol-4-yl)pyridine-3-carbonitrile chemical structure, C11H8ClN3S, CAS 246020-85-9
2-Chloro-6-methyl-5-(2-methyl-1,3-thiazol-4-yl)pyridine-3-carbonitrile
CAS 246020-85-9C11H8ClN3S
N-2-Propen-1-yl-4-(3-pyridinyl)-2-thiazolamine chemical structure, C11H11N3S, CAS 56541-08-3
N-2-Propen-1-yl-4-(3-pyridinyl)-2-thiazolamine
CAS 56541-08-3C11H11N3S
N-(4-(Pyridin-3-yl)thiazol-2-yl)propionamide chemical structure, C11H11N3OS, CAS 477544-79-9
N-(4-(Pyridin-3-yl)thiazol-2-yl)propionamide
CAS 477544-79-9C11H11N3OS
2-Methyl-N-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]propanamide chemical structure, C12H13N3OS, CAS 477544-81-3
2-Methyl-N-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]propanamide
CAS 477544-81-3C12H13N3OS
5-Bromo-4-(3-pyridyl)-2-aminothiazole chemical structure, C8H6BrN3S, CAS 1243839-09-9
5-Bromo-4-(3-pyridyl)-2-aminothiazole
CAS 1243839-09-9C8H6BrN3S
N-Methyl-4-(pyridin-3-yl)-1,3-thiazol-2-amine chemical structure, C9H9N3S, CAS 56541-06-1
N-Methyl-4-(pyridin-3-yl)-1,3-thiazol-2-amine
CAS 56541-06-1C9H9N3S
4-(3-Pyridinyl)-2-thiazolecarboxylic acid hydrazide chemical structure, C9H8N4OS, CAS 56601-50-4
4-(3-Pyridinyl)-2-thiazolecarboxylic acid hydrazide
CAS 56601-50-4C9H8N4OS
4-Pyridin-3-YL-thiazole-2-carboxylic acid ethyl ester chemical structure, C11H10N2O2S, CAS 56601-49-1
4-Pyridin-3-YL-thiazole-2-carboxylic acid ethyl ester
CAS 56601-49-1C11H10N2O2S
(4-Pyridin-3-yl-1,3-thiazol-2-yl)hydrazine chemical structure, C8H8N4S, CAS 139420-57-8
(4-Pyridin-3-yl-1,3-thiazol-2-yl)hydrazine
CAS 139420-57-8C8H8N4S
4-(Pyridin-3-yl)thiazol-2-amine hydrobromide chemical structure, C8H8BrN3S, CAS 147311-08-8
4-(Pyridin-3-yl)thiazol-2-amine hydrobromide
CAS 147311-08-8C8H8BrN3S
2-Chloro-3-(thiazol-4-yl)pyridine chemical structure, C8H5ClN2S, CAS 1417519-54-0
2-Chloro-3-(thiazol-4-yl)pyridine
CAS 1417519-54-0C8H5ClN2S
4-Chloro-3-(4-thiazolyl)pyridine chemical structure, C8H5ClN2S, CAS 1563533-54-9
4-Chloro-3-(4-thiazolyl)pyridine
CAS 1563533-54-9C8H5ClN2S
3-(4-Thiazolyl)-2-pyridinecarboxylic acid chemical structure, C9H6N2O2S, CAS 1607429-36-6
3-(4-Thiazolyl)-2-pyridinecarboxylic acid
CAS 1607429-36-6C9H6N2O2S
4-(Pyridin-3-yl)thiazole chemical structure, C8H6N2S, CAS 162704-76-9
4-(Pyridin-3-yl)thiazole
CAS 162704-76-9C8H6N2S
5-Methyl-4-(pyridin-3-yl)-1,3-thiazol-2-amine chemical structure, C9H9N3S, CAS 56541-26-5
5-Methyl-4-(pyridin-3-yl)-1,3-thiazol-2-amine
CAS 56541-26-5C9H9N3S
2-(4-(Pyridin-3-yl)thiazol-2-yl)acetonitrile chemical structure, C10H7N3S, CAS 1016859-62-3
2-(4-(Pyridin-3-yl)thiazol-2-yl)acetonitrile
CAS 1016859-62-3C10H7N3S
1-[4-(Pyridin-3-yl)-1,3-thiazol-2-yl]methanamine chemical structure, C9H9N3S, CAS 1019351-75-7
1-[4-(Pyridin-3-yl)-1,3-thiazol-2-yl]methanamine
CAS 1019351-75-7C9H9N3S
Pyridine, 2-bromo-5-(4-thiazolyl)- chemical structure, C8H5BrN2S, CAS 1142197-27-0
Pyridine, 2-bromo-5-(4-thiazolyl)-
CAS 1142197-27-0C8H5BrN2S
2-Amino-5-(thiazol-4-yl)pyridine chemical structure, C8H7N3S, CAS 1159819-24-5
2-Amino-5-(thiazol-4-yl)pyridine
CAS 1159819-24-5C8H7N3S
2-Bromo-5-(2-methylthiazol-4-yl)pyridine chemical structure, C9H7BrN2S, CAS 1142197-28-1
2-Bromo-5-(2-methylthiazol-4-yl)pyridine
CAS 1142197-28-1C9H7BrN2S