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Murcko scaffold

Ring system with 2 rings and 27 atoms

22 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
27
Chemicals
22
With full pages
2
Scaffold SMILES

O=C(CNC(=O)CNC(=O)OCc1ccccc1)NCCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)CNC(=O)OCc1ccccc1)NCCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

SK&F 107461 chemical structure, C37H53N5O9, CAS 126380-03-8
SK&F 107461
CAS 126380-03-8C37H53N5O9
Methyl n-[(benzyloxy)carbonyl]serylleucyltyrosinate chemical structure, C27H35N3O8
Methyl n-[(benzyloxy)carbonyl]serylleucyltyrosinate
C27H35N3O8
2-[2-(2-{[(Benzyloxy)carbonyl]amino}acetamido)acetamido]-3-phenylpropanoic acid chemical structure, C21H23N3O6, CAS 100428-07-7
2-[2-(2-{[(Benzyloxy)carbonyl]amino}acetamido)acetamido]-3-phenylpropanoic acid
CAS 100428-07-7C21H23N3O6
N-[(Benzyloxy)carbonyl]glycylglycylphenylalaninamide chemical structure, C21H24N4O5, CAS 75501-76-7
N-[(Benzyloxy)carbonyl]glycylglycylphenylalaninamide
CAS 75501-76-7C21H24N4O5
Z-Gly-Gly-Phe-OH chemical structure, C21H23N3O6, CAS 13171-93-2
Z-Gly-Gly-Phe-OH
CAS 13171-93-2C21H23N3O6
PS-II chemical structure, C29H39N3O5, CAS 133429-58-0
PS-II
CAS 133429-58-0C29H39N3O5
Z-Gly-gly-phe-chloromethylketone chemical structure, C22H24ClN3O5, CAS 35172-59-9
Z-Gly-gly-phe-chloromethylketone
CAS 35172-59-9C22H24ClN3O5
Z-Leu-Leu-Tyr-a-keto aldehyde chemical structure, C30H39N3O7, CAS 204649-66-1
Z-Leu-Leu-Tyr-a-keto aldehyde
CAS 204649-66-1C30H39N3O7
L-Phenylalanine, N-[N-[N-[(phenylmethoxy)carbonyl]-L-alanyl]-L-alanyl]- chemical structure, C23H27N3O6, CAS 19245-91-1
L-Phenylalanine, N-[N-[N-[(phenylmethoxy)carbonyl]-L-alanyl]-L-alanyl]-
CAS 19245-91-1C23H27N3O6
N-((Benzyloxy)carbonyl)-L-leucyl-N-((1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl)-L-leucinamide chemical structure, C30H40FN3O6, CAS 133410-84-1
N-((Benzyloxy)carbonyl)-L-leucyl-N-((1S)-3-fluoro-1-(4-hydroxybenzyl)-2-oxopropyl)-L-leucinamide
CAS 133410-84-1C30H40FN3O6
N-Benzyloxycarbonylglycyl-leucyl-phenylalanine chloromethyl ketone chemical structure, C26H32ClN3O5, CAS 41658-44-0
N-Benzyloxycarbonylglycyl-leucyl-phenylalanine chloromethyl ketone
CAS 41658-44-0C26H32ClN3O5
Methyl (2S)-3-phenyl-2-[[2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]acetyl]amino]propanoate chemical structure, C22H25N3O6, CAS 15027-03-9
Methyl (2S)-3-phenyl-2-[[2-[[2-(phenylmethoxycarbonylamino)acetyl]amino]acetyl]amino]propanoate
CAS 15027-03-9C22H25N3O6
L-Tyrosine, N-[N-[N-[(phenylmethoxy)carbonyl]-L-seryl]-L-leucyl]-, methyl ester chemical structure, C27H35N3O8, CAS 55517-95-8
L-Tyrosine, N-[N-[N-[(phenylmethoxy)carbonyl]-L-seryl]-L-leucyl]-, methyl ester
CAS 55517-95-8C27H35N3O8
L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-alanyl-N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]- chemical structure, C23H29N3O5, CAS 178910-89-9
L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-alanyl-N-[(1S)-1-(hydroxymethyl)-2-phenylethyl]-
CAS 178910-89-9C23H29N3O5
N-Cbz-glycyl-glycyl-D-phenylalanine chemical structure, C21H23N3O6, CAS 1802522-76-4
N-Cbz-glycyl-glycyl-D-phenylalanine
CAS 1802522-76-4C21H23N3O6
N-[(Benzyloxy)carbonyl]glycylglycyl-L-tyrosine chemical structure, C21H23N3O7, CAS 23234-49-3
N-[(Benzyloxy)carbonyl]glycylglycyl-L-tyrosine
CAS 23234-49-3C21H23N3O7
N-[(Benzyloxy)carbonyl]glycylglycyl-4-nitro-L-phenylalanine chemical structure, C21H22N4O8, CAS 61480-95-3
N-[(Benzyloxy)carbonyl]glycylglycyl-4-nitro-L-phenylalanine
CAS 61480-95-3C21H22N4O8
Z-Val-Gly-Phe-OH chemical structure, C24H29N3O6, CAS 138867-42-2
Z-Val-Gly-Phe-OH
CAS 138867-42-2C24H29N3O6
N-((Phenylmethoxy)carbonyl)glycyl-N-((1S)-1-formyl-2-(4-hydroxyphenyl)ethyl)-L-alaninamide chemical structure, C22H25N3O6, CAS 1189108-44-8
N-((Phenylmethoxy)carbonyl)glycyl-N-((1S)-1-formyl-2-(4-hydroxyphenyl)ethyl)-L-alaninamide
CAS 1189108-44-8C22H25N3O6
L-Alaninamide, N-[(phenylmethoxy)carbonyl]glycyl-N-[2-hydroxy-1-[(4-hydroxyphenyl)methyl]-2-sulfoethyl]-, sodium salt (1:1) chemical structure, C22H26N3NaO9S, CAS 1417334-25-8
L-Alaninamide, N-[(phenylmethoxy)carbonyl]glycyl-N-[2-hydroxy-1-[(4-hydroxyphenyl)methyl]-2-sulfoethyl]-, sodium salt (1:1)
CAS 1417334-25-8C22H26N3NaO9S
Methyl N-{[(4-methoxyphenyl)methoxy]carbonyl}glycyl-L-leucyl-L-phenylalaninate chemical structure, C27H35N3O7, CAS 90072-19-8
Methyl N-{[(4-methoxyphenyl)methoxy]carbonyl}glycyl-L-leucyl-L-phenylalaninate
CAS 90072-19-8C27H35N3O7
N-[(Benzyloxy)carbonyl]-L-alanyl-L-alanyl-4-azido-L-phenylalanine chemical structure, C23H26N6O6, CAS 53774-69-9
N-[(Benzyloxy)carbonyl]-L-alanyl-L-alanyl-4-azido-L-phenylalanine
CAS 53774-69-9C23H26N6O6