Murcko scaffold
Ring system with 2 rings and 27 atoms
298 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 27
- Chemicals
- 298
- With full pages
- 30
Scaffold SMILES
O=C(CCc1ccccc1)NCC(=O)NCC(=O)NCCc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 298 chemicals
Enkephalinamide-leu
CAS 60117-24-0C28H38N6O6
Enkephalinamide-met, ala(2)-
CAS 61090-95-7C28H38N6O6S
Enkephalin, Ser(2), Leu(5), Thr(6)-
CAS 75644-90-5C33H46N6O10
Dynorphin (1-8)
CAS 75790-53-3C46H72N14O10
Deltakephalin
CAS 85286-38-0C34H48N6O10
Phenylalanyl-leucyl-arginyl phenylalaninamide
CAS 80690-77-3C30H44N8O4
Enkephalin-leu, arg(6)-
CAS 75106-70-6C34H49N9O8
Adrenorphin
CAS 88377-68-8C44H69N15O9S
N-Methyltyrosyl-glycyl-glycyl-phenylalanyl-leucyl-arginyl-N-methyl-arginyl-leucyl ethylamide
CAS 103613-84-9C50H81N15O9
Met-enkephalinamide
CAS 60117-17-1C27H36N6O6S
Enkephalin-Met, Arg(6)-Gly(7)-Leu(8)-
CAS 80501-44-6C41H61N11O10S
H-Tyr-Ala-Gly-Phe-Met-OH
CAS 63058-21-9C28H37N5O7S
Enkephalin-Met, sulfoxide-
CAS 60283-51-4C27H35N5O8S
Tyrosyl-alanyl-glycyl-phenylalanyl-psi(thiomethylene)leucine
CAS 103834-43-1C29H40N4O6S
Tyrosyl-threonyl-glycyl-(4-azidophenylalanyl)-leucyl-threonine
CAS 95537-15-8C36H48F3N9O12
Enkephalin-met, arg(6)-
CAS 76310-14-0C33H47N9O8S
Tyrosyl-methionyl(O)-glycyl-ethylphenylalanine-2-acetylhydrazide
CAS 98849-86-6C31H44N6O9S
alpha-Lactorphin
CAS 105129-00-8C26H35N5O5
beta-Lactorphin
CAS 105129-01-9C30H43N5O5
Phenylalanyl-leucyl-arginyl-phenylalanine
CAS 122075-70-1C30H43N7O5
Tyrosyl-seryl(o-tert-butyl)-glycyl-phenylalanyl-leucyl-threonine
CAS 111035-56-4C37H54N6O10
Tyrosyl-seryl(o-t-butyl)-glycyl-phenylalanyl-leucyl-threonine(o-t-butyl)
CAS 111035-57-5C41H62N6O10
Sdrnflrfamide
CAS 113611-67-9C47H72N16O12
Enkephalin, arg(2)-leu(5)-
CAS 76939-27-0C32H46N8O7
- Tyrosyl-cysteinyl(stbu)-glycyl-phenylalanyl-leucyl-threonyl(O-t-butyl)131766-24-0C41H62N6O9S
- Fulicin137182-25-3C32H43N7O8
- Phenylalanyl-arginyl-valyl-phenylalanine144548-33-4C29H41N7O5
- Neuropeptide DF2149471-11-4C44H67N15O10
- Enkephalin, ala(2)-val(5)-78859-44-6C28H37N5O7
- Enkephalin, ala(2)-valnh2(5)-78873-50-4C28H38N6O6
- Enkephalin-Leu, sulfonated80632-52-6C28H37N5O10S
- Enkephalin-leu, 4'-bromo-phe(4)-89705-56-6C28H36BrN5O7
- Enkephalin-Met, 4'-bromo-Phe(4)-89705-57-7C27H34BrN5O7S
- 1 suppliersAF1 neuropeptide130092-56-7C45H69N13O10
- Enkephalin, alanh2(5)-77044-76-9C25H32N6O6
- Enkephalin-Met, Tyr-O-sulfate81788-49-0C27H35N5O10S2
- Daeatal103614-28-4C56H93N19O10
- Enkephalin-met, lys(6)-75909-25-0C33H47N7O8S
- beta-Lipotropin (60-65)60117-19-3C33H47N9O8S
- Rat gastrin C-terminal pentagastrin80063-35-0C34H46N6O10S
- Enkephalin-met, arg(6,7)-76496-10-1C39H59N13O9S
- Diallyl G127808-81-5C38H53N5O8
- 16 suppliersMetenkefalin58569-55-4C27H35N5O7S
- 6-(Tyrosylglycylglycylphenylalanylleucyl)-D-glucopyranose133733-37-6C34H47N5O12
- 14 suppliersLeu-enkephalin58822-25-6C28H37N5O7
- L-Phenylalanine, N-(N-(N-(N,O-bis(1,1-dimethylethoxy)carbonyl)-L-tyrosyl)-D-alanylglycyl)-145594-19-0C33H44N4O10
- Daaccal103614-06-8C51H81N19O10S2
- beta-Endorphin (1-9)59481-79-7C45H66N10O15S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(CCCCCCCCC(=O)OC1CCNCC1)OC1CCNCC16 chemicals
c1ccc(CCNCCCCCCNCCc2ccccc2)cc15 chemicals
c1ccc(OCCCCCCCCCCOc2ccccc2)cc14 chemicals
O=C(NCCCCCCNC(=O)Oc1cccnc1)Oc1cccnc13 chemicals
O=C(C=Cc1ccccc1)NCCCCNC(=O)C=Cc1ccccc13 chemicalscc1](/scaffold/PJYVBMNAFDUKRW-UHFFFAOYSA-N/structure.svg)
c1cc[n+](CCCCCCCCCCCC[n+]2ccccc2)cc13 chemicals
O=C(CCCCC(=O)NCCc1ccccc1)NCCc1ccccc13 chemicals
O=C(NCCNCc1ccccc1)C(=O)NCCNCc1ccccc12 chemicals
O=C(NCCCCNCCCNC(=O)c1ccccc1)c1ccccc12 chemicals
O=C(CCCCCCCCC(=O)Nc1ccccc1)Nc1ccccc12 chemicals
O=C(CNC(=O)CNC(=O)OCc1ccccc1)NCCc1ccccc12 chemicals
O=C(NCCCCCCNC(=O)Nc1ccccc1)Nc1ccccc12 chemicals