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Murcko scaffold

5-(Piperidin-1-ylmethyl)thiazole scaffold

140 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 12
Chemicals: 140
With full pages: 5

Scaffold SMILES

c1ncc(CN2CCCCC2)s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5-(Piperidin-1-ylmethyl)thiazole page

Murcko scaffold c1ncc(CN2CCCCC2)s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 140 chemicals

N-[5-(1-Piperidinylmethyl)-1,3-thiazol-2-yl]acetamide chemical structure, C11H17N3OS, CAS 100139-84-2

N-[5-(1-Piperidinylmethyl)-1,3-thiazol-2-yl]acetamide

CAS 100139-84-2C₁₁H₁₇N₃OS

Methyl 5-(1-piperidinylmethyl)-1,3-thiazol-2-ylcarbamate chemical structure, C11H17N3O2S, CAS 540512-25-2

Methyl 5-(1-piperidinylmethyl)-1,3-thiazol-2-ylcarbamate

CAS 540512-25-2C₁₁H₁₇N₃O₂S

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-methylpiperidine chemical structure, C10H15ClN2S, CAS 478064-75-4

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-4-methylpiperidine

CAS 478064-75-4C₁₀H₁₅ClN₂S

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]piperidine-4-carboxylic acid chemical structure, C10H13ClN2O2S, CAS 939986-49-9

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]piperidine-4-carboxylic acid

CAS 939986-49-9C₁₀H₁₃ClN₂O₂S

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]piperidine chemical structure, C9H13ClN2S, CAS 339104-71-1

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]piperidine

CAS 339104-71-1C₉H₁₃ClN₂S

Ethyl 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-4-piperidinecarboxylate chemical structure, C12H17ClN2O2S, CAS 453557-58-9

Ethyl 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-4-piperidinecarboxylate

CAS 453557-58-9C₁₂H₁₇ClN₂O₂S

Methyl 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-4-piperidinecarboxylate chemical structure, C11H15ClN2O2S, CAS 454473-62-2

Methyl 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-4-piperidinecarboxylate

CAS 454473-62-2C₁₁H₁₅ClN₂O₂S

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]piperidine-4-carboxylic acid hydrochloride chemical structure, C10H14Cl2N2O2S, CAS 1052404-18-8

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]piperidine-4-carboxylic acid hydrochloride

CAS 1052404-18-8C₁₀H₁₄Cl₂N₂O₂S

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-3-methylpiperidine chemical structure, C10H15ClN2S, CAS 478064-79-8

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-3-methylpiperidine

CAS 478064-79-8C₁₀H₁₅ClN₂S

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methylpiperidine chemical structure, C10H15ClN2S, CAS 478064-78-7

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-methylpiperidine

CAS 478064-78-7C₁₀H₁₅ClN₂S

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2,6-dimethylpiperidine chemical structure, C11H17ClN2S, CAS 923676-61-3

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2,6-dimethylpiperidine

CAS 923676-61-3C₁₁H₁₇ClN₂S

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-ethylpiperidine chemical structure, C11H17ClN2S, CAS 885950-50-5

1-[(2-Chloro-1,3-thiazol-5-yl)methyl]-2-ethylpiperidine

CAS 885950-50-5C₁₁H₁₇ClN₂S

5-(1-Piperidinylmethyl)-2-thiazolamine chemical structure, C9H15N3S, CAS 3008-58-0

5-(1-Piperidinylmethyl)-2-thiazolamine

CAS 3008-58-0C₉H₁₅N₃S

1-(2-Chloro-thiazol-5-ylmethyl)-piperidin-4-ol chemical structure, C9H13ClN2OS, CAS 939986-50-2

1-(2-Chloro-thiazol-5-ylmethyl)-piperidin-4-ol

CAS 939986-50-2C₉H₁₃ClN₂OS

1-((2-Chlorothiazol-5-yl)methyl)piperidin-3-ol chemical structure, C9H13ClN2OS, CAS 939986-51-3

1-((2-Chlorothiazol-5-yl)methyl)piperidin-3-ol

CAS 939986-51-3C₉H₁₃ClN₂OS

[1-(2-Chloro-thiazol-5-ylmethyl)-piperidin-3-yl]-methanol chemical structure, C10H15ClN2OS, CAS 939986-52-4

[1-(2-Chloro-thiazol-5-ylmethyl)-piperidin-3-yl]-methanol

CAS 939986-52-4C₁₀H₁₅ClN₂OS

1,1-Dimethylethyl N-(1-((2-chloro-5-thiazolyl)methyl)-4-piperidinyl)carbamate chemical structure, C14H22ClN3O2S, CAS 939986-54-6

1,1-Dimethylethyl N-(1-((2-chloro-5-thiazolyl)methyl)-4-piperidinyl)carbamate

CAS 939986-54-6C₁₄H₂₂ClN₃O₂S

tert-Butyl (1-((2-chloro-1,3-thiazol-5-yl)methyl)piperidin-3-yl)carbamate chemical structure, C14H22ClN3O2S, CAS 939986-55-7

tert-Butyl (1-((2-chloro-1,3-thiazol-5-yl)methyl)piperidin-3-yl)carbamate

CAS 939986-55-7C₁₄H₂₂ClN₃O₂S

1-(2-Chloro-thiazol-5-ylmethyl)-piperidin-4-ylamine dihydrochloride chemical structure, C9H16Cl3N3S, CAS 1185312-10-0

1-(2-Chloro-thiazol-5-ylmethyl)-piperidin-4-ylamine dihydrochloride

CAS 1185312-10-0C₉H₁₆Cl₃N₃S

1-(2-Chloro-thiazol-5-ylmethyl)-piperidin-3-ylamine dihydrochloride chemical structure, C9H16Cl3N3S, CAS 1185311-97-0

1-(2-Chloro-thiazol-5-ylmethyl)-piperidin-3-ylamine dihydrochloride

CAS 1185311-97-0C₉H₁₆Cl₃N₃S

3-Methyl-1-[(2-methyl-1,3-thiazol-5-yl)methyl]piperidin-4-amine chemical structure, C11H19N3S, CAS 1249691-31-3

3-Methyl-1-[(2-methyl-1,3-thiazol-5-yl)methyl]piperidin-4-amine

CAS 1249691-31-3C₁₁H₁₉N₃S

4-Methyl-1-[(1,3-thiazol-5-yl)methyl]piperidine chemical structure, C10H16N2S, CAS 1864292-58-9

4-Methyl-1-[(1,3-thiazol-5-yl)methyl]piperidine

CAS 1864292-58-9C₁₀H₁₆N₂S

1-(Thiazol-5-ylmethyl)piperidin-3-amine hydrochloride chemical structure, C9H16ClN3S, CAS 1261232-59-0

1-(Thiazol-5-ylmethyl)piperidin-3-amine hydrochloride

CAS 1261232-59-0C₉H₁₆ClN₃S

N-Methyl-1-(thiazol-5-ylmethyl)piperidin-4-amine hydrochloride chemical structure, C10H18ClN3S, CAS 1261233-42-4

N-Methyl-1-(thiazol-5-ylmethyl)piperidin-4-amine hydrochloride

CAS 1261233-42-4C₁₀H₁₈ClN₃S