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Murcko scaffold

7H,8H-Imidazo[1,5-a]pyrazin-8-one scaffold

25 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
25
With full pages
6
Scaffold SMILES

O=c1[nH]ccn2cncc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 7H,8H-Imidazo[1,5-a]pyrazin-8-one page
Murcko scaffold O=c1[nH]ccn2cncc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

Ethyl 8-oxoimidazo[1,5-a]pyrazine-7-carboxylate chemical structure, C9H9N3O3, CAS 56468-19-0
Ethyl 8-oxoimidazo[1,5-a]pyrazine-7-carboxylate
CAS 56468-19-0C9H9N3O3
7H,8H-Imidazo[1,5-a]pyrazin-8-one chemical structure, C6H5N3O, CAS 56468-21-4
7H,8H-Imidazo[1,5-a]pyrazin-8-one
CAS 56468-21-4C6H5N3O
3-Methylimidazo[1,5-a]pyrazin-8(7H)-one chemical structure, C7H7N3O, CAS 56468-22-5
3-Methylimidazo[1,5-a]pyrazin-8(7H)-one
CAS 56468-22-5C7H7N3O
Imidazo[1,5-a]pyrazine-1-carboxylic acid,3-(ethylthio)-7,8-dihydro-8-oxo- chemical structure, C9H9N3O3S, CAS 852021-80-8
Imidazo[1,5-a]pyrazine-1-carboxylic acid,3-(ethylthio)-7,8-dihydro-8-oxo-
CAS 852021-80-8C9H9N3O3S
5-Bromo-7H,8H-imidazo(1,5-a)pyrazin-8-one chemical structure, C6H4BrN3O, CAS 849200-66-4
5-Bromo-7H,8H-imidazo(1,5-a)pyrazin-8-one
CAS 849200-66-4C6H4BrN3O
Ethyl 5,8-Dihydroxyimidazo[1,5-a]pyrazine-1-carboxylate chemical structure, C9H9N3O4, CAS 1256633-37-0
Ethyl 5,8-Dihydroxyimidazo[1,5-a]pyrazine-1-carboxylate
CAS 1256633-37-0C9H9N3O4
Ethyl 8-Hydroxyimidazo[1,5-a]pyrazine-1-carboxylate chemical structure, C9H9N3O3, CAS 1256633-36-9
Ethyl 8-Hydroxyimidazo[1,5-a]pyrazine-1-carboxylate
CAS 1256633-36-9C9H9N3O3
3-Isopropylimidazo[1,5-a]pyrazin-8-ol chemical structure, C9H11N3O, CAS 1506675-85-9
3-Isopropylimidazo[1,5-a]pyrazin-8-ol
CAS 1506675-85-9C9H11N3O
3-Bromo-7H,8H-imidazo[1,5-a]pyrazin-8-one chemical structure, C6H4BrN3O, CAS 1534625-82-5
3-Bromo-7H,8H-imidazo[1,5-a]pyrazin-8-one
CAS 1534625-82-5C6H4BrN3O
Methyl 8-oxo-7H,8H-imidazo[1,5-a]pyrazine-3-carboxylate chemical structure, C8H7N3O3, CAS 1529455-82-0
Methyl 8-oxo-7H,8H-imidazo[1,5-a]pyrazine-3-carboxylate
CAS 1529455-82-0C8H7N3O3
6-Methyl-8-oxo-7,8-dihydroimidazo[1,5-a]pyrazine-1-carboxylic acid chemical structure, C8H7N3O3, CAS 1708428-08-3
6-Methyl-8-oxo-7,8-dihydroimidazo[1,5-a]pyrazine-1-carboxylic acid
CAS 1708428-08-3C8H7N3O3
6-Methylimidazo[1,5-A]pyrazin-8-ol chemical structure, C7H7N3O, CAS 2240985-82-2
6-Methylimidazo[1,5-A]pyrazin-8-ol
CAS 2240985-82-2C7H7N3O
5-Bromo-7-methylimidazo[1,5-a]pyrazin-8(7H)-one chemical structure, C7H6BrN3O, CAS 1706750-15-3
5-Bromo-7-methylimidazo[1,5-a]pyrazin-8(7H)-one
CAS 1706750-15-3C7H6BrN3O
5-Bromo-6-chloroimidazo[1,5-a]pyrazin-8-ol chemical structure, C6H3BrClN3O, CAS 1858215-47-0
5-Bromo-6-chloroimidazo[1,5-a]pyrazin-8-ol
CAS 1858215-47-0C6H3BrClN3O
3-(tert-Butyl)imidazo[1,5-a]pyrazin-8-ol chemical structure, C10H13N3O, CAS 2092765-83-6
3-(tert-Butyl)imidazo[1,5-a]pyrazin-8-ol
CAS 2092765-83-6C10H13N3O
3-Propylimidazo[1,5-a]pyrazin-8(7H)-one chemical structure, C9H11N3O, CAS 2031270-00-3
3-Propylimidazo[1,5-a]pyrazin-8(7H)-one
CAS 2031270-00-3C9H11N3O
3-Bromo-6-methylimidazo[1,5-a]pyrazin-8(7H)-one chemical structure, C7H6BrN3O, CAS 2031270-02-5
3-Bromo-6-methylimidazo[1,5-a]pyrazin-8(7H)-one
CAS 2031270-02-5C7H6BrN3O
3-Isopropyl-6-methylimidazo[1,5-a]pyrazin-8(7H)-one chemical structure, C10H13N3O, CAS 2031271-58-4
3-Isopropyl-6-methylimidazo[1,5-a]pyrazin-8(7H)-one
CAS 2031271-58-4C10H13N3O
3-(1-Methoxy-2-methylpropan-2-yl)-6-methylimidazo[1,5-a]pyrazin-8(7H)-one chemical structure, C12H17N3O2, CAS 2031271-54-0
3-(1-Methoxy-2-methylpropan-2-yl)-6-methylimidazo[1,5-a]pyrazin-8(7H)-one
CAS 2031271-54-0C12H17N3O2
3-Bromo-6-ethylimidazo[1,5-a]pyrazin-8(7H)-one chemical structure, C8H8BrN3O, CAS 2031271-10-8
3-Bromo-6-ethylimidazo[1,5-a]pyrazin-8(7H)-one
CAS 2031271-10-8C8H8BrN3O
3-Bromo-7H,8H-imidazo(1,5-a)pyrazin-8-one hydrochloride chemical structure, C6H5BrClN3O, CAS 2060063-35-4
3-Bromo-7H,8H-imidazo(1,5-a)pyrazin-8-one hydrochloride
CAS 2060063-35-4C6H5BrClN3O
5-Bromo-6-methylimidazo[1,5-A]pyrazin-8-ol chemical structure, C7H6BrN3O, CAS 2240985-85-5
5-Bromo-6-methylimidazo[1,5-A]pyrazin-8-ol
CAS 2240985-85-5C7H6BrN3O
8-Oxo-7H,8H-imidazo[1,5-a]pyrazine-5-carboxylic acid chemical structure, C7H5N3O3, CAS 2567504-22-5
8-Oxo-7H,8H-imidazo[1,5-a]pyrazine-5-carboxylic acid
CAS 2567504-22-5C7H5N3O3
7H,8H-Imidazo[1,5-a]pyrazin-8-one hydrochloride chemical structure, C6H6ClN3O, CAS 2172576-07-5
7H,8H-Imidazo[1,5-a]pyrazin-8-one hydrochloride
CAS 2172576-07-5C6H6ClN3O