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Murcko scaffold

Ring system with 3 rings and 12 atoms

85 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
12
Chemicals
85
With full pages
9
Scaffold SMILES

C1OC2COC3OCOC3C2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1OC2COC3OCOC3C2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 85 chemicals

(2,2,7,7-Tetramethyltetrahydro-2H,3aH,7H-bis(1,3)dioxolo(4,5-b:4',5'-d)pyran-3a-yl)methyl sulfamate chemical structure, C12H21NO8S, CAS 1217455-55-4
(2,2,7,7-Tetramethyltetrahydro-2H,3aH,7H-bis(1,3)dioxolo(4,5-b:4',5'-d)pyran-3a-yl)methyl sulfamate
CAS 1217455-55-4C12H21NO8S
1,2:3,4-Di-O-isopropylidene-D-galactopyranose chemical structure, C12H20O6, CAS 536723-20-3
1,2:3,4-Di-O-isopropylidene-D-galactopyranose
CAS 536723-20-3C12H20O6
6-Desoxy-6-n-octylamino-1,2-3,4-di-O-isopropylidenegalactopyranose chemical structure, C20H37NO5, CAS 153237-23-1
6-Desoxy-6-n-octylamino-1,2-3,4-di-O-isopropylidenegalactopyranose
CAS 153237-23-1C20H37NO5
Dimethylthiocarbamoyl isopropylidene galactopyranose chemical structure, C15H25NO6S, CAS 16795-64-5
Dimethylthiocarbamoyl isopropylidene galactopyranose
CAS 16795-64-5C15H25NO6S
1-(4,4,11,11-Tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)prop-2-en-1-ol chemical structure, C14H22O6, CAS 4640-86-2
1-(4,4,11,11-Tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)prop-2-en-1-ol
CAS 4640-86-2C14H22O6
(2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methyl acetate chemical structure, C14H22O7, CAS 4860-78-0
(2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methyl acetate
CAS 4860-78-0C14H22O7
Dimethyl-[(4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)methylselanyl]arsane chemical structure, C14H25AsO5Se, CAS 67816-36-8
Dimethyl-[(4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)methylselanyl]arsane
CAS 67816-36-8C14H25AsO5Se
1-(4,4,11,11-Tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)prop-2-yn-1-one chemical structure, C14H18O6, CAS 65784-43-2
1-(4,4,11,11-Tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)prop-2-yn-1-one
CAS 65784-43-2C14H18O6
1-(4,4,11,11-Tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)prop-2-en-1-one chemical structure, C14H20O6, CAS 72369-63-2
1-(4,4,11,11-Tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)prop-2-en-1-one
CAS 72369-63-2C14H20O6
2,2,7,7-Tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-carboxylic acid chemical structure, C12H18O7, CAS 6974-48-7
2,2,7,7-Tetramethyl-tetrahydro-bis[1,3]dioxolo[4,5-b:4',5'-d]pyran-3a-carboxylic acid
CAS 6974-48-7C12H18O7
Dimethyl-[(4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)methylsulfanyl]arsane chemical structure, C14H25AsO5S, CAS 67816-31-3
Dimethyl-[(4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecan-8-yl)methylsulfanyl]arsane
CAS 67816-31-3C14H25AsO5S
4,4,11,11-Tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecane-8-carboxylic acid chemical structure, C12H18O7, CAS 1093405-83-4
4,4,11,11-Tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecane-8-carboxylic acid
CAS 1093405-83-4C12H18O7
1,2:3,4-Di-O-isopropylidene-a-D-galacturonide chemical structure, C12H18O7, CAS 25253-46-7
1,2:3,4-Di-O-isopropylidene-a-D-galacturonide
CAS 25253-46-7C12H18O7
1,2:3,4-Di-O-isopropylidene-alpha-D-galactopyranose chemical structure, C12H20O6, CAS 4064-06-6
1,2:3,4-Di-O-isopropylidene-alpha-D-galactopyranose
CAS 4064-06-6C12H20O6
1,2:3,4-Bis-O-(1-methylethylidene)-beta-L-arabinopyranose chemical structure, C11H18O5, CAS 27820-98-0
1,2:3,4-Bis-O-(1-methylethylidene)-beta-L-arabinopyranose
CAS 27820-98-0C11H18O5
alpha-D-Glucopyranose, 1,2:3,4-bis-O-(1-methylethylidene)-, butanoate chemical structure, C16H26O7, CAS 127702-00-5
alpha-D-Glucopyranose, 1,2:3,4-bis-O-(1-methylethylidene)-, butanoate
CAS 127702-00-5C16H26O7
Topiramate chemical structure, C12H21NO8S, CAS 97240-79-4
Topiramate
CAS 97240-79-4C12H21NO8S
2,3-4,5-Di-O-isopropylidene-1-O-methyl-beta-fructopyranose chemical structure, C13H22O6, CAS 60885-04-3
2,3-4,5-Di-O-isopropylidene-1-O-methyl-beta-fructopyranose
CAS 60885-04-3C13H22O6
((3aS,5R,5aR,8aS,8bR)-2,2,7,7-Tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methanol chemical structure, C12H20O6, CAS 496879-67-5
((3aS,5R,5aR,8aS,8bR)-2,2,7,7-Tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl)methanol
CAS 496879-67-5C12H20O6
Tetramethyltetrahydro D-tagatose methanol chemical structure, C12H20O6, CAS 133907-41-2
Tetramethyltetrahydro D-tagatose methanol
CAS 133907-41-2C12H20O6
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, methyl((((1-(methylthio)ethylidene)amino)oxy)carbonyl)amidosulfite chemical structure, C17H28N2O9S2, CAS 81861-98-5
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, methyl((((1-(methylthio)ethylidene)amino)oxy)carbonyl)amidosulfite
CAS 81861-98-5C17H28N2O9S2
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, ((((2-(dimethylamino)-1-(methylthio)-2-oxoethylidene)amino)oxy)carbonyl)methylamidosulfite chemical structure, C19H31N3O10S2, CAS 81862-03-5
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, ((((2-(dimethylamino)-1-(methylthio)-2-oxoethylidene)amino)oxy)carbonyl)methylamidosulfite
CAS 81862-03-5C19H31N3O10S2
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate, mixt. with alpha,alpha-dimethylbenzeneethanamine chemical structure, C22H36N2O8S, CAS 960078-81-3
beta-D-Fructopyranose, 2,3:4,5-bis-O-(1-methylethylidene)-, 1-sulfamate, mixt. with alpha,alpha-dimethylbenzeneethanamine
CAS 960078-81-3C22H36N2O8S
1,2,3,4-DI-O-Isopropylidene-alpha-D-galacturonic acid methyl ester chemical structure, C13H20O7, CAS 18524-41-9
1,2,3,4-DI-O-Isopropylidene-alpha-D-galacturonic acid methyl ester
CAS 18524-41-9C13H20O7