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Murcko scaffold

5H,6H,7H,8H-Pyrido(4,3-d)pyrimidine scaffold

201 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
201
With full pages
28
Scaffold SMILES

c1ncc2c(n1)CCNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5H,6H,7H,8H-Pyrido(4,3-d)pyrimidine page
Murcko scaffold c1ncc2c(n1)CCNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 201 chemicals

5H,6H,7H,8H-Pyrido(4,3-d)pyrimidine chemical structure, C7H9N3, CAS 192869-50-4
5H,6H,7H,8H-Pyrido(4,3-d)pyrimidine
CAS 192869-50-4C7H9N3
5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidin-2-amine chemical structure, C7H10N4, CAS 124458-31-7
5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidin-2-amine
CAS 124458-31-7C7H10N4
5H,6H,7H,8H-Pyrido[4,3-d]pyrimidine-2,4-diamine chemical structure, C7H11N5, CAS 39949-17-2
5H,6H,7H,8H-Pyrido[4,3-d]pyrimidine-2,4-diamine
CAS 39949-17-2C7H11N5
2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine chemical structure, C8H11N3, CAS 676994-65-3
2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
CAS 676994-65-3C8H11N3
2,6-Dimethyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine chemical structure, C9H13N3, CAS 66521-81-1
2,6-Dimethyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
CAS 66521-81-1C9H13N3
6-Methyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-2-ylamine chemical structure, C8H12N4, CAS 66521-82-2
6-Methyl-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidin-2-ylamine
CAS 66521-82-2C8H12N4
6-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine chemical structure, C8H11N3, CAS 66521-83-3
6-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
CAS 66521-83-3C8H11N3
{5H,6H,7H,8H-Pyrido[4,3-d]pyrimidin-2-yl}urea chemical structure, C8H11N5O, CAS 929973-38-6
{5H,6H,7H,8H-Pyrido[4,3-d]pyrimidin-2-yl}urea
CAS 929973-38-6C8H11N5O
2-{5H,6H,7H,8H-Pyrido[4,3-d]pyrimidin-2-yl}propan-2-amine chemical structure, C10H16N4, CAS 2060035-36-9
2-{5H,6H,7H,8H-Pyrido[4,3-d]pyrimidin-2-yl}propan-2-amine
CAS 2060035-36-9C10H16N4
tert-Butyl 2,4-dichloro-7,8-dihydropyrido(4,3-d)pyrimidine-6(5H)-carboxylate chemical structure, C12H15Cl2N3O2, CAS 635698-56-5
tert-Butyl 2,4-dichloro-7,8-dihydropyrido(4,3-d)pyrimidine-6(5H)-carboxylate
CAS 635698-56-5C12H15Cl2N3O2
2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride chemical structure, C8H12ClN3, CAS 210538-73-1
2-Methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride
CAS 210538-73-1C8H12ClN3
5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine hydrochloride chemical structure, C7H10ClN3, CAS 210538-68-4
5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine hydrochloride
CAS 210538-68-4C7H10ClN3
5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine dihydrochloride chemical structure, C7H11Cl2N3, CAS 157327-49-6
5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine dihydrochloride
CAS 157327-49-6C7H11Cl2N3
N,N-Dimethyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine chemical structure, C9H14N4, CAS 578713-43-6
N,N-Dimethyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine
CAS 578713-43-6C9H14N4
4-Chloro-6-methyl-5H,6H,7H,8H-pyrido(4,3-d)pyrimidine chemical structure, C8H10ClN3, CAS 1258650-41-7
4-Chloro-6-methyl-5H,6H,7H,8H-pyrido(4,3-d)pyrimidine
CAS 1258650-41-7C8H10ClN3
2-(Propan-2-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine chemical structure, C10H15N3, CAS 954230-61-6
2-(Propan-2-yl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine
CAS 954230-61-6C10H15N3
2-Chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine chemical structure, C7H8ClN3, CAS 944901-59-1
2-Chloro-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
CAS 944901-59-1C7H8ClN3
1,1-Dimethylethyl 7,8-dihydro-2-[[(2-methoxyethyl)amino]methyl]pyrido[4,3-d]pyrimidine-6(5H)-carboxylate chemical structure, C16H26N4O3, CAS 601516-18-1
1,1-Dimethylethyl 7,8-dihydro-2-[[(2-methoxyethyl)amino]methyl]pyrido[4,3-d]pyrimidine-6(5H)-carboxylate
CAS 601516-18-1C16H26N4O3
tert-Butyl 2-formyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate chemical structure, C13H17N3O3, CAS 601516-17-0
tert-Butyl 2-formyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate
CAS 601516-17-0C13H17N3O3
1,1-Dimethylethyl 7,8-dihydro-2-(hydroxymethyl)pyrido[4,3-d]pyrimidine-6(5H)-carboxylate chemical structure, C13H19N3O3, CAS 601514-65-2
1,1-Dimethylethyl 7,8-dihydro-2-(hydroxymethyl)pyrido[4,3-d]pyrimidine-6(5H)-carboxylate
CAS 601514-65-2C13H19N3O3
tert-Butyl 7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate chemical structure, C12H17N3O2, CAS 192869-49-1
tert-Butyl 7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate
CAS 192869-49-1C12H17N3O2
tert-Butyl 7,8-dihydro-2-(methylsulfonyl)pyrido[4,3-d]pyrimidine-6(5H)-carboxylate chemical structure, C13H19N3O4S, CAS 259809-79-5
tert-Butyl 7,8-dihydro-2-(methylsulfonyl)pyrido[4,3-d]pyrimidine-6(5H)-carboxylate
CAS 259809-79-5C13H19N3O4S
tert-Butyl 2-(methylthio)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate chemical structure, C13H19N3O2S, CAS 259809-78-4
tert-Butyl 2-(methylthio)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate
CAS 259809-78-4C13H19N3O2S
4-Chloro-5,6,7,8-tetrahydro-2-(methylthio)pyrido[4,3-D]pyrimidine chemical structure, C8H10ClN3S, CAS 944902-03-8
4-Chloro-5,6,7,8-tetrahydro-2-(methylthio)pyrido[4,3-D]pyrimidine
CAS 944902-03-8C8H10ClN3S