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Murcko scaffold

Ring system with 3 rings and 18 atoms

37 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
37
With full pages
2
Scaffold SMILES

O=C(Cc1coc2ccccc12)Nc1nncs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1coc2ccccc12)Nc1nncs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

2-(5-Ethyl-1-benzofuran-3-yl)-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C15H15N3O2S2, CAS 831231-12-0
2-(5-Ethyl-1-benzofuran-3-yl)-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 831231-12-0C15H15N3O2S2
2-(6-Methoxybenzofuran-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C14H13N3O3S, CAS 848066-61-5
2-(6-Methoxybenzofuran-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 848066-61-5C14H13N3O3S
2-(5-Methyl-1-benzofuran-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C14H13N3O2S, CAS 831242-86-5
2-(5-Methyl-1-benzofuran-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 831242-86-5C14H13N3O2S
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(5-methyl-1-benzofuran-3-yl)acetamide chemical structure, C15H15N3O2S, CAS 879951-14-1
N-(5-Ethyl-1,3,4-thiadiazol-2-yl)-2-(5-methyl-1-benzofuran-3-yl)acetamide
CAS 879951-14-1C15H15N3O2S
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C16H17N3O2S, CAS 879952-20-2
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 879952-20-2C16H17N3O2S
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-[5-(prop-2-en-1-ylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C17H17N3O2S2, CAS 866247-70-3
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-[5-(prop-2-en-1-ylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 866247-70-3C17H17N3O2S2
2-(6-Methyl-1-benzofuran-3-yl)-N-[5-(prop-2-en-1-ylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C16H15N3O2S2, CAS 879758-41-5
2-(6-Methyl-1-benzofuran-3-yl)-N-[5-(prop-2-en-1-ylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 879758-41-5C16H15N3O2S2
2-[5-(Propan-2-yl)-1-benzofuran-3-yl]-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C18H21N3O2S, CAS 879942-07-1
2-[5-(Propan-2-yl)-1-benzofuran-3-yl]-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 879942-07-1C18H21N3O2S
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H19N3O2S, CAS 879952-36-0
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 879952-36-0C17H19N3O2S
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C17H19N3O2S, CAS 879952-28-0
2-(6,7-Dimethyl-1-benzofuran-3-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 879952-28-0C17H19N3O2S
2-(5-Methyl-1-benzofuran-3-yl)-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C16H17N3O2S, CAS 879951-48-1
2-(5-Methyl-1-benzofuran-3-yl)-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 879951-48-1C16H17N3O2S
2-(5-Methyl-1-benzofuran-3-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C16H17N3O2S, CAS 879937-10-7
2-(5-Methyl-1-benzofuran-3-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 879937-10-7C16H17N3O2S
2-(6-Methyl-1-benzofuran-3-yl)-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C14H13N3O2S2, CAS 880791-08-2
2-(6-Methyl-1-benzofuran-3-yl)-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 880791-08-2C14H13N3O2S2
2-(6-Methyl-1-benzofuran-3-yl)-N-[5-(propylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C16H17N3O2S2, CAS 880791-02-6
2-(6-Methyl-1-benzofuran-3-yl)-N-[5-(propylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 880791-02-6C16H17N3O2S2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C17H19N3O2S, CAS 879959-40-7
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(5-propyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 879959-40-7C17H19N3O2S
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C17H19N3O2S, CAS 879947-42-9
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 879947-42-9C17H19N3O2S
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C18H21N3O2S, CAS 873080-68-3
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(2-methylpropyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 873080-68-3C18H21N3O2S
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide chemical structure, C15H15N3O2S, CAS 879938-12-2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)acetamide
CAS 879938-12-2C15H15N3O2S
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C15H15N3O2S2, CAS 881443-48-7
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 881443-48-7C15H15N3O2S2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(propylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C17H19N3O2S2, CAS 879945-40-1
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(propylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 879945-40-1C17H19N3O2S2
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(prop-2-en-1-ylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C17H17N3O2S2, CAS 879945-46-7
2-(4,6-Dimethyl-1-benzofuran-3-yl)-N-[5-(prop-2-en-1-ylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 879945-46-7C17H17N3O2S2
2-(5-Ethyl-1-benzofuran-3-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C17H19N3O2S, CAS 879942-54-8
2-(5-Ethyl-1-benzofuran-3-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 879942-54-8C17H19N3O2S
2-(5-Methyl-1-benzofuran-3-yl)-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C14H13N3O2S2, CAS 879951-21-0
2-(5-Methyl-1-benzofuran-3-yl)-N-[5-(methylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 879951-21-0C14H13N3O2S2
2-(5-Methyl-1-benzofuran-3-yl)-N-[5-(prop-2-en-1-ylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide chemical structure, C16H15N3O2S2, CAS 879951-34-5
2-(5-Methyl-1-benzofuran-3-yl)-N-[5-(prop-2-en-1-ylsulfanyl)-1,3,4-thiadiazol-2-yl]acetamide
CAS 879951-34-5C16H15N3O2S2