CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 29 atoms

31 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
29
Chemicals
31
With full pages
2
Scaffold SMILES

O=C(CSc1cn(CC(=O)N2CCOCC2)c2ccccc12)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1cn(CC(=O)N2CCOCC2)c2ccccc12)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)-N-(m-tolyl)acetamide chemical structure, C23H25N3O3S, CAS 878054-37-6
2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)-N-(m-tolyl)acetamide
CAS 878054-37-6C23H25N3O3S
N-Mesityl-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C25H29N3O3S, CAS 878054-55-8
N-Mesityl-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878054-55-8C25H29N3O3S
N-(4-Ethylphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C24H27N3O3S, CAS 878054-58-1
N-(4-Ethylphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878054-58-1C24H27N3O3S
N-(3-Chloro-4-methylphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C23H24ClN3O3S, CAS 878053-29-3
N-(3-Chloro-4-methylphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878053-29-3C23H24ClN3O3S
N-(4-Ethoxyphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C24H27N3O4S, CAS 878053-41-9
N-(4-Ethoxyphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878053-41-9C24H27N3O4S
N-(2,5-Dimethoxyphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C24H27N3O5S, CAS 878053-45-3
N-(2,5-Dimethoxyphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878053-45-3C24H27N3O5S
Ethyl 2-(2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamido)benzoate chemical structure, C25H27N3O5S, CAS 878053-64-6
Ethyl 2-(2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamido)benzoate
CAS 878053-64-6C25H27N3O5S
N-(4-Acetylphenyl)-2-((1-(2-(2,6-dimethylmorpholino)-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C26H29N3O4S, CAS 893998-58-8
N-(4-Acetylphenyl)-2-((1-(2-(2,6-dimethylmorpholino)-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 893998-58-8C26H29N3O4S
2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)-N-(o-tolyl)acetamide chemical structure, C23H25N3O3S, CAS 878054-34-3
2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)-N-(o-tolyl)acetamide
CAS 878054-34-3C23H25N3O3S
2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)-N-(p-tolyl)acetamide chemical structure, C23H25N3O3S, CAS 878054-40-1
2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)-N-(p-tolyl)acetamide
CAS 878054-40-1C23H25N3O3S
N-(2,4-Dimethylphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C24H27N3O3S, CAS 878054-49-0
N-(2,4-Dimethylphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878054-49-0C24H27N3O3S
N-(3,5-Dimethylphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C24H27N3O3S, CAS 878054-52-5
N-(3,5-Dimethylphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878054-52-5C24H27N3O3S
N-(4-Chlorophenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C22H22ClN3O3S, CAS 878053-23-7
N-(4-Chlorophenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878053-23-7C22H22ClN3O3S
N-(4-Bromophenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C22H22BrN3O3S, CAS 878053-25-9
N-(4-Bromophenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878053-25-9C22H22BrN3O3S
N-(2-Methoxyphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C23H25N3O4S, CAS 878053-33-9
N-(2-Methoxyphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878053-33-9C23H25N3O4S
N-(4-Methoxyphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C23H25N3O4S, CAS 878053-37-3
N-(4-Methoxyphenyl)-2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 878053-37-3C23H25N3O4S
N-(2,4-Dimethoxyphenyl)-2-({1-[2-(morpholin-4-yl)-2-oxoethyl]-1H-indol-3-yl}sulfanyl)acetamide chemical structure, C24H27N3O5S, CAS 878053-43-1
N-(2,4-Dimethoxyphenyl)-2-({1-[2-(morpholin-4-yl)-2-oxoethyl]-1H-indol-3-yl}sulfanyl)acetamide
CAS 878053-43-1C24H27N3O5S
2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide chemical structure, C23H22F3N3O3S, CAS 878053-56-6
2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide
CAS 878053-56-6C23H22F3N3O3S
Methyl 4-(2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamido)benzoate chemical structure, C24H25N3O5S, CAS 878053-68-0
Methyl 4-(2-((1-(2-morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamido)benzoate
CAS 878053-68-0C24H25N3O5S
4-(2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamido)benzamide chemical structure, C23H24N4O4S, CAS 878054-09-2
4-(2-((1-(2-Morpholino-2-oxoethyl)-1H-indol-3-yl)thio)acetamido)benzamide
CAS 878054-09-2C23H24N4O4S
2-((1-(2-(2,6-Dimethylmorpholino)-2-oxoethyl)-1H-indol-3-yl)thio)-N-(2-fluorophenyl)acetamide chemical structure, C24H26FN3O3S, CAS 892742-60-8
2-((1-(2-(2,6-Dimethylmorpholino)-2-oxoethyl)-1H-indol-3-yl)thio)-N-(2-fluorophenyl)acetamide
CAS 892742-60-8C24H26FN3O3S
N-(3-Chlorophenyl)-2-((1-(2-(2,6-dimethylmorpholino)-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C24H26ClN3O3S, CAS 892742-66-4
N-(3-Chlorophenyl)-2-((1-(2-(2,6-dimethylmorpholino)-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 892742-66-4C24H26ClN3O3S
N-(4-Chlorophenyl)-2-({1-[2-(2,6-dimethylmorpholin-4-yl)-2-oxoethyl]-1H-indol-3-yl}sulfanyl)acetamide chemical structure, C24H26ClN3O3S, CAS 892742-72-2
N-(4-Chlorophenyl)-2-({1-[2-(2,6-dimethylmorpholin-4-yl)-2-oxoethyl]-1H-indol-3-yl}sulfanyl)acetamide
CAS 892742-72-2C24H26ClN3O3S
N-(4-Bromophenyl)-2-((1-(2-(2,6-dimethylmorpholino)-2-oxoethyl)-1H-indol-3-yl)thio)acetamide chemical structure, C24H26BrN3O3S, CAS 892742-78-8
N-(4-Bromophenyl)-2-((1-(2-(2,6-dimethylmorpholino)-2-oxoethyl)-1H-indol-3-yl)thio)acetamide
CAS 892742-78-8C24H26BrN3O3S