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Murcko scaffold

2-Pyrrolidinone, 5-phenyl- scaffold

410 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
410
With full pages
24
Scaffold SMILES

O=C1CCC(c2ccccc2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Pyrrolidinone, 5-phenyl- page
Murcko scaffold O=C1CCC(c2ccccc2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 410 chemicals

2-Pyrrolidinone, 5-phenyl- chemical structure, C10H11NO, CAS 22050-10-8
2-Pyrrolidinone, 5-phenyl-
CAS 22050-10-8C10H11NO
5-Ethyl-5-phenylpyrrolidinone chemical structure, C12H15NO, CAS 3482-72-2
5-Ethyl-5-phenylpyrrolidinone
CAS 3482-72-2C12H15NO
5-Methyl-5-phenyl-2-pyrrolidinone chemical structure, C11H13NO, CAS 5578-98-3
5-Methyl-5-phenyl-2-pyrrolidinone
CAS 5578-98-3C11H13NO
2-Phenyl-2-propyl-3,4-dihydro-2H-pyrrol-5-ol chemical structure, C13H17NO, CAS 6139-25-9
2-Phenyl-2-propyl-3,4-dihydro-2H-pyrrol-5-ol
CAS 6139-25-9C13H17NO
2-Pyrrolidinone, 5-isopropyl-5-phenyl- chemical structure, C13H17NO, CAS 6139-26-0
2-Pyrrolidinone, 5-isopropyl-5-phenyl-
CAS 6139-26-0C13H17NO
2-Butyl-2-phenyl-3,4-dihydro-2H-pyrrol-5-ol chemical structure, C14H19NO, CAS 6139-27-1
2-Butyl-2-phenyl-3,4-dihydro-2H-pyrrol-5-ol
CAS 6139-27-1C14H19NO
2-Ethyl-2-(4-methoxyphenyl)-3,4-dihydro-2H-pyrrol-5-ol chemical structure, C13H17NO2, CAS 6139-29-3
2-Ethyl-2-(4-methoxyphenyl)-3,4-dihydro-2H-pyrrol-5-ol
CAS 6139-29-3C13H17NO2
2-Pyrrolidinone, 5-(p-ethoxyphenyl)-5-ethyl- chemical structure, C14H19NO2, CAS 6139-30-6
2-Pyrrolidinone, 5-(p-ethoxyphenyl)-5-ethyl-
CAS 6139-30-6C14H19NO2
5-Hydroxy-1-methyl-5-phenylpyrrolidin-2-one chemical structure, C11H13NO2, CAS 23132-30-1
5-Hydroxy-1-methyl-5-phenylpyrrolidin-2-one
CAS 23132-30-1C11H13NO2
5-(2-Fluorophenyl)-3-hydroxy-1-methylpyrrolidin-2-one chemical structure, C11H12FNO2, CAS 909074-65-3
5-(2-Fluorophenyl)-3-hydroxy-1-methylpyrrolidin-2-one
CAS 909074-65-3C11H12FNO2
5-(3-Fluorophenyl)-3-hydroxy-1-methylpyrrolidin-2-one chemical structure, C11H12FNO2, CAS 908077-29-2
5-(3-Fluorophenyl)-3-hydroxy-1-methylpyrrolidin-2-one
CAS 908077-29-2C11H12FNO2
3-Hydroxy-1-methyl-5-phenylpyrrolidin-2-one chemical structure, C11H13NO2, CAS 22278-37-1
3-Hydroxy-1-methyl-5-phenylpyrrolidin-2-one
CAS 22278-37-1C11H13NO2
5-(4-Fluorophenyl)-3-hydroxy-1-methylpyrrolidin-2-one chemical structure, C11H12FNO2, CAS 909193-87-9
5-(4-Fluorophenyl)-3-hydroxy-1-methylpyrrolidin-2-one
CAS 909193-87-9C11H12FNO2
1-Methyl-5-oxo-2-phenylpyrrolidine-2-carboxylic acid chemical structure, C12H13NO3, CAS 330454-05-2
1-Methyl-5-oxo-2-phenylpyrrolidine-2-carboxylic acid
CAS 330454-05-2C12H13NO3
1-Dodecyl-5-oxo-2-phenylpyrrolidine-3-carboxylic acid chemical structure, C23H35NO3, CAS 80722-12-9
1-Dodecyl-5-oxo-2-phenylpyrrolidine-3-carboxylic acid
CAS 80722-12-9C23H35NO3
2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(4-(trifluoromethyl)phenyl)- chemical structure, C12H12F3NO2, CAS 93040-67-6
2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(4-(trifluoromethyl)phenyl)-
CAS 93040-67-6C12H12F3NO2
2-Pyrrolidinone, 1-butyl-5-hydroxy-5-(3-(trifluoromethyl)phenyl)- chemical structure, C15H18F3NO2, CAS 93040-68-7
2-Pyrrolidinone, 1-butyl-5-hydroxy-5-(3-(trifluoromethyl)phenyl)-
CAS 93040-68-7C15H18F3NO2
2-Pyrrolidinone, 5-(3-chlorophenyl)-5-hydroxy-1-methyl- chemical structure, C11H12ClNO2, CAS 93040-74-5
2-Pyrrolidinone, 5-(3-chlorophenyl)-5-hydroxy-1-methyl-
CAS 93040-74-5C11H12ClNO2
2-Pyrrolidinone, 5-hydroxy-1-propyl-5-(3-(trifluoromethyl)phenyl)- chemical structure, C14H16F3NO2, CAS 93061-24-6
2-Pyrrolidinone, 5-hydroxy-1-propyl-5-(3-(trifluoromethyl)phenyl)-
CAS 93061-24-6C14H16F3NO2
5-Hydroxy-1-methyl-5-(3-methylphenyl)pyrrolidin-2-one chemical structure, C12H15NO2, CAS 59618-42-7
5-Hydroxy-1-methyl-5-(3-methylphenyl)pyrrolidin-2-one
CAS 59618-42-7C12H15NO2
2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)- chemical structure, C12H12F3NO2, CAS 56948-73-3
2-Pyrrolidinone, 5-hydroxy-1-methyl-5-(3-(trifluoromethyl)phenyl)-
CAS 56948-73-3C12H12F3NO2
2-Pyrrolidinone, 1-ethyl-5-hydroxy-5-(3-(trifluoromethyl)phenyl)- chemical structure, C13H14F3NO2, CAS 56948-74-4
2-Pyrrolidinone, 1-ethyl-5-hydroxy-5-(3-(trifluoromethyl)phenyl)-
CAS 56948-74-4C13H14F3NO2
2-Pyrrolidinone, 5-hydroxy-5-(3-(trifluoromethyl)phenyl)- chemical structure, C11H10F3NO2, CAS 56948-75-5
2-Pyrrolidinone, 5-hydroxy-5-(3-(trifluoromethyl)phenyl)-
CAS 56948-75-5C11H10F3NO2
Dimethyl 1-methyl-2-oxo-5-phenyl-3,4-pyrrolidinedicarboxylate chemical structure, C15H17NO5, CAS 468714-34-3
Dimethyl 1-methyl-2-oxo-5-phenyl-3,4-pyrrolidinedicarboxylate
CAS 468714-34-3C15H17NO5