Murcko scaffold
2-Benzylcyclopentanone scaffold
71 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 13
- Chemicals
- 71
- With full pages
- 8
Scaffold SMILES
O=C1CCCC1Cc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 71 chemicals
Loxoprofen
CAS 68767-14-6C15H18O3
3-(1-Benzyl-2-oxocyclopentyl)propanoic acid
CAS 3645-83-8C15H18O3
Cyclopentanepropionic acid, 1-(p-chlorophenyl)-2-oxo-
CAS 2700-03-0C15H17ClO3
Cyclopentanepropionic acid, 1-(o-methoxybenzyl)-2-oxo-
CAS 2700-04-1C16H20O4
Cyclopentanepropionic acid, 1-(o-chlorobenzyl)-2-oxo-
CAS 2700-13-2C15H17ClO3
Ethyl 1-benzyl-2-oxocyclopentanecarboxylate
CAS 50984-08-2C15H18O3
![4-Methyl-2-[(4-nitrophenyl)methyl]-3-oxocyclopentane-1-carboxylic acid chemical structure, C14H15NO5, CAS 18124-81-7](/s/MNXDLQBGRRDUMJ-UHFFFAOYSA-N.svg)
4-Methyl-2-[(4-nitrophenyl)methyl]-3-oxocyclopentane-1-carboxylic acid
CAS 18124-81-7C14H15NO5
![Methyl 1-[(4-chlorophenyl)methyl]-2-oxocyclopentane-1-carboxylate chemical structure, C14H15ClO3, CAS 115851-73-5](/s/XEFHZYULZFZBFU-UHFFFAOYSA-N.svg)
Methyl 1-[(4-chlorophenyl)methyl]-2-oxocyclopentane-1-carboxylate
CAS 115851-73-5C14H15ClO3
2-Benzylcyclopentanone
CAS 2867-63-2C12H14O
2-(4-Iodobenzyl)cyclopentanone
CAS 500763-98-4C12H13IO
(AlphaR)-alpha-methyl-4-(((1S)-2-oxocyclopentyl)methyl)benzeneacetic acid
CAS 90319-73-6C15H18O3
o-Loxoprofen
CAS 1027400-34-5C15H18O3
2-(4-((1-(Methoxycarbonyl)-2-oxocyclopentyl)methyl)phenyl)propanoic Acid
CAS 1027957-36-3C17H20O5
m-Loxoprofen
CAS 1026471-88-4C15H18O3
![Cyclopentanone, 2-[(2-bromophenyl)methyl]- chemical structure, C12H13BrO, CAS 132452-24-5](/s/IHJKRELWANHJRL-UHFFFAOYSA-N.svg)
Cyclopentanone, 2-[(2-bromophenyl)methyl]-
CAS 132452-24-5C12H13BrO
![Benzonitrile, 4-[(2-oxocyclopentyl)methyl]- chemical structure, C13H13NO, CAS 125116-22-5](/s/FDADFPIDKGHHHY-UHFFFAOYSA-N.svg)
Benzonitrile, 4-[(2-oxocyclopentyl)methyl]-
CAS 125116-22-5C13H13NO
![(2R)-2-[(R)-Hydroxy(phenyl)methyl]cyclopentan-1-one chemical structure, C12H14O2, CAS 145679-44-3](/s/UWJDDKHDOWAZDA-JQWIXIFHSA-N.svg)
(2R)-2-[(R)-Hydroxy(phenyl)methyl]cyclopentan-1-one
CAS 145679-44-3C12H14O2
Methyl 1-benzyl-2-oxocyclopentane carboxylate
CAS 10386-81-9C14H16O3
![Cyclopentanone, 2-[phenyl[(trimethylsilyl)oxy]methyl]- chemical structure, C15H22O2Si, CAS 223905-13-3](/s/MCPJTCBVKHDKCN-UHFFFAOYSA-N.svg)
Cyclopentanone, 2-[phenyl[(trimethylsilyl)oxy]methyl]-
CAS 223905-13-3C15H22O2Si
![Cyclopentanone, 2-[(R)-hydroxy(4-nitrophenyl)methyl]-, (2R)- chemical structure, C12H13NO4, CAS 349628-52-0](/s/CIYBYDAJXJZQNN-JQWIXIFHSA-N.svg)
Cyclopentanone, 2-[(R)-hydroxy(4-nitrophenyl)methyl]-, (2R)-
CAS 349628-52-0C12H13NO4
![2-[(4-Chlorophenyl)methyl]cyclopentan-1-one chemical structure, C12H13ClO, CAS 2866-68-4](/s/OPLDIHWEFBYKBR-UHFFFAOYSA-N.svg)
2-[(4-Chlorophenyl)methyl]cyclopentan-1-one
CAS 2866-68-4C12H13ClO
2-(Hydroxy-(4-nitrophenyl)methyl)cyclopentanone
CAS 205759-66-6C12H13NO4
![Cyclopentanone, 2-[(1R)-2-nitro-1-phenylethyl]-, (2S)- chemical structure, C13H15NO3, CAS 359876-14-5](/s/RIJDKVQQVVKDPB-RYUDHWBXSA-N.svg)
Cyclopentanone, 2-[(1R)-2-nitro-1-phenylethyl]-, (2S)-
CAS 359876-14-5C13H15NO3
Cyclopentanone, 2-methyl-2-(phenylmethyl)-, (2R)-
CAS 831170-19-5C13H16O
- 4 suppliers5-(4-Chlorobenzyl)-2,2-dimethylcyclopentanone115851-28-0C14H17ClO
- Loxoprofen impurity 17308279-38-1C18H22O5
- Methyl 1-[(4-chlorophenyl)methyl]-3-methyl-2-oxocyclopentane-1-carboxylate115851-54-2C15H17ClO3
- 2-[(2-Nitrophenyl)methyl]cyclopentan-1-one548461-24-1C12H13NO3
- 2-(2-Phenylpropan-2-yl)cyclopentan-1-one77152-13-7C14H18O
- 2-(4,4-Dimethyl-3-oxo-1-phenylpentyl)cyclopentan-1-one78530-94-6C18H24O2
- [(2,4-Dihydroxyphenyl)(2-oxocyclopentyl)methyl]propanedioic acid79339-17-6C15H16O7
- (2R)-2-[4-[[(1R)-2-Oxocyclopentyl]methyl]phenyl]propanoic acid90319-74-7C15H18O3
- 1 suppliers2-[(4-Acetylphenyl)methyl]cyclopentan-1-one96824-28-1C14H16O2
- 2-(1-Phenyl-2-propen-1-yl)cyclopentanone858264-14-9C14H16O
- (1S)-2-Benzyl-3-oxocyclopentanecarboxylic acid1212741-63-3C13H14O3
- 2-(4-Chlorobenzyl)-5-isopropylcyclopentanone115851-44-0C15H19ClO
- 4-(2-Oxocyclopentan-1-ylmethyl)phenylacetic Acid68767-15-7C14H16O3
- Loxoprofen impurity 38639857-67-3C14H18O
- 2-Benzyl-3-oxocyclopentane-1-carbaldehyde61659-08-3C13H14O2
- 4-[(2-Oxocyclopentyl)methyl]benzamide189119-77-5C13H15NO2
- 31 suppliersLoxoprofen sodium80382-23-6C15H17NaO3
- 26 suppliersSodium 2-(4-(2-oxocyclopentylmethyl)phenyl)propionate dihydrate226721-96-6C15H21NaO5
- 1 suppliersMethyl 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate81762-92-7C16H20O3
- (2R)-2-[(R)-(2-Chlorophenyl)hydroxymethyl]cyclopentanone1068139-77-4C12H13ClO2
- 2-(3-Chlorobenzyl)cyclopentan-1-one1225919-27-6C12H13ClO
- 2-[(2-Methoxyphenyl)methyl]cyclopentan-1-one2866-63-9C13H16O2
- 1-((4-Fluorophenyl)methyl)-2-oxocyclopentane-1-carbonitrile1493457-80-9C13H12FNO
- 2-(4-(Oct-1-yn-1-yl)benzyl)cyclopentanone1135585-44-2C20H26O
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cn2cccn2)cc1271 chemicals
c1ccc(CN2CCCC2)cc1172 chemicals
O=S(=O)(c1ccccc1)N1CCCC1146 chemicals
c1ccc(Cn2ccnc2)cc1107 chemicals![Scaffold c1ccc(N=c2[nH]ccs2)cc1](/scaffold/OGVGQYZRJXSMGC-UHFFFAOYSA-N/structure.svg)
c1ccc(N=c2[nH]ccs2)cc198 chemicals
O=C1NC(=S)SC1=Cc1ccccc186 chemicals
O=C(c1ccccc1)N1CCCC186 chemicals
O=S(=O)(c1ccccc1)n1ccnc184 chemicals![Scaffold O=C(c1ccccc1)c1cc[nH]c1](/scaffold/DSNSKSWTLGZGAN-UHFFFAOYSA-N/structure.svg)
O=C(c1ccccc1)c1cc[nH]c177 chemicals
c1ccc(Cn2ccnn2)cc177 chemicals
c1ccc(Cc2cncs2)cc175 chemicals
c1ccc(Cn2cccc2)cc163 chemicals