Murcko scaffold
1-Phenylmethanesulfonyl-piperidine scaffold
216 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 16
- Chemicals
- 216
- With full pages
- 12
Scaffold SMILES
O=S(=O)(Cc1ccccc1)N1CCCCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 216 chemicals
1-Phenylmethanesulfonyl-piperidine
CAS 16358-39-7C12H17NO2S
Methyl 1-(benzylsulfonyl)piperidine-4-carboxylate
CAS 349612-92-6C14H19NO4S
Ethyl 1-(benzylsulfonyl)piperidine-3-carboxylate
CAS 349612-84-6C15H21NO4S
1-(Benzylsulfonyl)-4-methylpiperidine
CAS 331847-65-5C13H19NO2S
Ethyl 1-benzylsulfonylpiperidine-4-carboxylate
CAS 326902-56-1C15H21NO4S
![Ethyl 1-[(4-chlorobenzyl)sulfonyl]-4-piperidinecarboxylate chemical structure, C15H20ClNO4S, CAS 827619-91-0](/s/YVFJMGDDQJHTLZ-UHFFFAOYSA-N.svg)
Ethyl 1-[(4-chlorobenzyl)sulfonyl]-4-piperidinecarboxylate
CAS 827619-91-0C15H20ClNO4S
1-Benzylsulfonyl-3-methylpiperidine
CAS 330469-60-8C13H19NO2S
![1-[(4-Chlorobenzyl)sulfonyl]-3-methylpiperidine chemical structure, C13H18ClNO2S, CAS 827619-75-0](/s/RETHJJBQOLOLEQ-UHFFFAOYSA-N.svg)
1-[(4-Chlorobenzyl)sulfonyl]-3-methylpiperidine
CAS 827619-75-0C13H18ClNO2S
![Ethyl 1-[(4-chlorobenzyl)sulfonyl]piperidine-3-carboxylate chemical structure, C15H20ClNO4S, CAS 827620-06-4](/s/CAEHZHBVXZQJFF-UHFFFAOYSA-N.svg)
Ethyl 1-[(4-chlorobenzyl)sulfonyl]piperidine-3-carboxylate
CAS 827620-06-4C15H20ClNO4S
Methyl 1-((2-chlorobenzyl)sulfonyl)piperidine-4-carboxylate
CAS 878985-35-4C14H18ClNO4S
![1-[(4-Chlorobenzyl)sulfonyl]piperidine-4-carboxamide chemical structure, C13H17ClN2O3S, CAS 878986-15-3](/s/RMFIFPUYQBOBSK-UHFFFAOYSA-N.svg)
1-[(4-Chlorobenzyl)sulfonyl]piperidine-4-carboxamide
CAS 878986-15-3C13H17ClN2O3S
1-(Benzylsulfonyl)-2-methylpiperidine
CAS 331847-68-8C13H19NO2S
1-Phenylmethanesulfonylpiperidine-3-carboxylic acid
CAS 891392-82-8C13H17NO4S
1-(Benzylsulfonyl)piperidin-4-amine
CAS 209917-52-2C12H18N2O2S
1-(Benzylsulfonyl)piperidine-4-carboxylic acid
CAS 891392-29-3C13H17NO4S
![1-[(2,6-Dichlorobenzyl)sulfonyl]piperidine-3-carboxamide chemical structure, C13H16Cl2N2O3S, CAS 928893-51-0](/s/YWAAKUJMVZWQIB-UHFFFAOYSA-N.svg)
1-[(2,6-Dichlorobenzyl)sulfonyl]piperidine-3-carboxamide
CAS 928893-51-0C13H16Cl2N2O3S
![1-[(3,4-Dichlorobenzyl)sulfonyl]-N-methylpiperidine-3-carboxamide chemical structure, C14H18Cl2N2O3S, CAS 928985-13-1](/s/SMRAXNRIUCTAOR-UHFFFAOYSA-N.svg)
1-[(3,4-Dichlorobenzyl)sulfonyl]-N-methylpiperidine-3-carboxamide
CAS 928985-13-1C14H18Cl2N2O3S
![1-[(2,4-Dichlorobenzyl)sulfonyl]piperidine-4-carboxamide chemical structure, C13H16Cl2N2O3S, CAS 928972-12-7](/s/UXKMCICGJQNDEP-UHFFFAOYSA-N.svg)
1-[(2,4-Dichlorobenzyl)sulfonyl]piperidine-4-carboxamide
CAS 928972-12-7C13H16Cl2N2O3S
![1-[(4-Fluorobenzyl)sulfonyl]-4-methylpiperidine chemical structure, C13H18FNO2S, CAS 950253-41-5](/s/IXFHEOXVIGLCSJ-UHFFFAOYSA-N.svg)
1-[(4-Fluorobenzyl)sulfonyl]-4-methylpiperidine
CAS 950253-41-5C13H18FNO2S
1-((4-Bromobenzyl)sulfonyl)piperidine
CAS 950256-94-7C12H16BrNO2S
1-(Benzylsulfonyl)-N-(butan-2-yl)piperidine-4-carboxamide
CAS 931940-50-0C17H26N2O3S
![N-(Butan-2-yl)-1-[(2-chlorobenzyl)sulfonyl]piperidine-4-carboxamide chemical structure, C17H25ClN2O3S, CAS 954745-37-0](/s/ZANTXTLBGIZTLM-UHFFFAOYSA-N.svg)
N-(Butan-2-yl)-1-[(2-chlorobenzyl)sulfonyl]piperidine-4-carboxamide
CAS 954745-37-0C17H25ClN2O3S
![1-[(4-Fluorobenzyl)sulfonyl]-N-(prop-2-en-1-yl)piperidine-4-carboxamide chemical structure, C16H21FN2O3S, CAS 955169-28-5](/s/LGAHVRBDOAWJSE-UHFFFAOYSA-N.svg)
1-[(4-Fluorobenzyl)sulfonyl]-N-(prop-2-en-1-yl)piperidine-4-carboxamide
CAS 955169-28-5C16H21FN2O3S
![N-tert-Butyl-1-[(4-fluorobenzyl)sulfonyl]piperidine-4-carboxamide chemical structure, C17H25FN2O3S, CAS 955169-43-4](/s/SFXGDMZMYBEVSC-UHFFFAOYSA-N.svg)
N-tert-Butyl-1-[(4-fluorobenzyl)sulfonyl]piperidine-4-carboxamide
CAS 955169-43-4C17H25FN2O3S
- 1-[(3-Chlorobenzyl)sulfonyl]piperidine-4-carboxamide952954-10-8C13H17ClN2O3S
- 1-[(3-Chlorobenzyl)sulfonyl]-N-(2-methylpropyl)piperidine-4-carboxamide952903-11-6C17H25ClN2O3S
- N-(Butan-2-yl)-1-[(3-chlorobenzyl)sulfonyl]piperidine-4-carboxamide952922-87-1C17H25ClN2O3S
- N-(Butan-2-yl)-1-[(2-methylbenzyl)sulfonyl]piperidine-4-carboxamide952903-90-1C18H28N2O3S
- 1-[(2-Fluorobenzyl)sulfonyl]-N-(2-methylpropyl)piperidine-4-carboxamide952907-05-0C17H25FN2O3S
- N-tert-Butyl-1-[(2-fluorobenzyl)sulfonyl]piperidine-4-carboxamide952936-29-7C17H25FN2O3S
- 1-[(2-Fluorobenzyl)sulfonyl]-N-(2-methoxyethyl)piperidine-4-carboxamide952907-09-4C16H23FN2O4S
- 1-[(2-Chloro-6-fluorobenzyl)sulfonyl]piperidine-4-carboxamide952908-63-3C13H16ClFN2O3S
- 1-[(3,4-Dichlorobenzyl)sulfonyl]-4-methylpiperidine950251-22-6C13H17Cl2NO2S
- tert-Butyl [1-(benzylsulfonyl)piperidin-4-yl]methylcarbamate891375-35-2C18H28N2O4S
- 1-[(4-Nitrophenyl)methanesulfonyl]piperidine1029603-15-3C12H16N2O4S
- 4-[(Piperidine-1-sulfonyl)methyl]benzonitrile1029603-11-9C13H16N2O2S
- 4-((Piperidin-1-ylsulfonyl)methyl)aniline1036522-46-9C12H18N2O2S
- Methyl 4-[(piperidine-1-sulfonyl)methyl]benzoate1029603-13-1C14H19NO4S
- {4-[(Piperidine-1-sulfonyl)methyl]phenyl}methanamine1036525-74-2C13H20N2O2S
- 1-{[(3-Nitrophenyl)methane]sulfonyl}piperidine1091954-75-4C12H16N2O4S
- 2-[(Piperidine-1-sulfonyl)methyl]benzonitrile1041515-38-1C13H16N2O2S
- (2-(((4-Methylpiperidin-1-yl)sulfonyl)methyl)phenyl)methanamine1039990-73-2C14H22N2O2S
- {2-[(Piperidine-1-sulfonyl)methyl]phenyl}methanamine1042513-21-2C13H20N2O2S
- 1-((4-Aminobenzyl)sulfonyl)piperidin-4-ol1040022-33-0C12H18N2O3S
- 4-[(Piperidin-1-ylsulfonyl)methyl]benzamide1120278-73-0C13H18N2O3S
- 4-(((3,5-Dimethylpiperidin-1-yl)sulfonyl)methyl)aniline1036444-86-6C14H22N2O2S
- 1-(Phenylmethane)sulfonylpiperidin-3-amine1019527-84-4C12H18N2O2S
- 1-[(4-Fluorobenzyl)sulfonyl]piperidine-4-carboxylic acid1099112-80-7C13H16FNO4S
Related scaffolds
Same ring framework with different atoms or bond orders
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O=C(Nc1ccccn1)c1ccccc1120 chemicals