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Murcko scaffold

4-(Pyridin-4-yl)pyrimidine scaffold

92 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
92
With full pages
5
Scaffold SMILES

c1cc(-c2ccncn2)ccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyridin-4-yl)pyrimidine page
Murcko scaffold c1cc(-c2ccncn2)ccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 92 chemicals

2-N,2-N-dimethyl-6-pyridin-4-ylpyrimidine-2,4-diamine chemical structure, C11H13N5, CAS 53434-95-0
2-N,2-N-dimethyl-6-pyridin-4-ylpyrimidine-2,4-diamine
CAS 53434-95-0C11H13N5
2-Chloro-4-(2-fluoropyridin-4-yl)pyrimidine chemical structure, C9H5ClFN3, CAS 361147-25-3
2-Chloro-4-(2-fluoropyridin-4-yl)pyrimidine
CAS 361147-25-3C9H5ClFN3
4-(Pyridin-4-yl)pyrimidin-2-amine chemical structure, C9H8N4, CAS 66521-70-8
4-(Pyridin-4-yl)pyrimidin-2-amine
CAS 66521-70-8C9H8N4
2-Methyl-4-(pyridin-4-yl)pyrimidine-5-carboxylic acid chemical structure, C11H9N3O2, CAS 400076-51-9
2-Methyl-4-(pyridin-4-yl)pyrimidine-5-carboxylic acid
CAS 400076-51-9C11H9N3O2
N,2-dimethyl-4-(4-pyridinyl)-5-pyrimidinecarboxamide chemical structure, C12H12N4O, CAS 400076-52-0
N,2-dimethyl-4-(4-pyridinyl)-5-pyrimidinecarboxamide
CAS 400076-52-0C12H12N4O
Methyl 2-methyl-4-(4-pyridinyl)-5-pyrimidinecarboxylate chemical structure, C12H11N3O2, CAS 400074-78-4
Methyl 2-methyl-4-(4-pyridinyl)-5-pyrimidinecarboxylate
CAS 400074-78-4C12H11N3O2
2-Methyl-4-(pyridin-4-yl)pyrimidine chemical structure, C10H9N3, CAS 66748-53-6
2-Methyl-4-(pyridin-4-yl)pyrimidine
CAS 66748-53-6C10H9N3
4-(Pyridin-4-yl)pyrimidine chemical structure, C9H7N3, CAS 53345-78-1
4-(Pyridin-4-yl)pyrimidine
CAS 53345-78-1C9H7N3
Cyanamide, [4-(4-pyridinyl)-2-pyrimidinyl]- chemical structure, C10H7N5, CAS 66521-67-3
Cyanamide, [4-(4-pyridinyl)-2-pyrimidinyl]-
CAS 66521-67-3C10H7N5
5-Methyl-4-(4-pyridyl)pyrimidin-2-amine chemical structure, C10H10N4, CAS 66521-77-5
5-Methyl-4-(4-pyridyl)pyrimidin-2-amine
CAS 66521-77-5C10H10N4
4-Methyl-6-pyridin-4-ylpyrimidin-2-amine chemical structure, C10H10N4, CAS 90916-53-3
4-Methyl-6-pyridin-4-ylpyrimidin-2-amine
CAS 90916-53-3C10H10N4
4-Chloro-2-methyl-6-(pyridin-4-yl)pyrimidine chemical structure, C10H8ClN3, CAS 103555-32-4
4-Chloro-2-methyl-6-(pyridin-4-yl)pyrimidine
CAS 103555-32-4C10H8ClN3
4-Chloro-6-pyridin-4-ylpyrimidine chemical structure, C9H6ClN3, CAS 954232-36-1
4-Chloro-6-pyridin-4-ylpyrimidine
CAS 954232-36-1C9H6ClN3
4-Chloro-6-(pyridin-4-yl)pyrimidin-2-amine chemical structure, C9H7ClN4, CAS 53421-90-2
4-Chloro-6-(pyridin-4-yl)pyrimidin-2-amine
CAS 53421-90-2C9H7ClN4
2-Chloro-4-(pyridin-4-yl)pyrimidine chemical structure, C9H6ClN3, CAS 208936-45-2
2-Chloro-4-(pyridin-4-yl)pyrimidine
CAS 208936-45-2C9H6ClN3
4-Bromo-6-(pyridin-4-yl)pyrimidine chemical structure, C9H6BrN3, CAS 1159820-28-6
4-Bromo-6-(pyridin-4-yl)pyrimidine
CAS 1159820-28-6C9H6BrN3
2-Methyl-6-(pyridin-4-yl)pyrimidin-4-amine chemical structure, C10H10N4, CAS 1159818-03-7
2-Methyl-6-(pyridin-4-yl)pyrimidin-4-amine
CAS 1159818-03-7C10H10N4
2-Bromo-4-(4-pyridyl)pyrimidine chemical structure, C9H6BrN3, CAS 1215071-41-2
2-Bromo-4-(4-pyridyl)pyrimidine
CAS 1215071-41-2C9H6BrN3
2-(Methylsulfinyl)-4-(4-pyridinyl)pyrimidine chemical structure, C10H9N3OS, CAS 1353502-42-7
2-(Methylsulfinyl)-4-(4-pyridinyl)pyrimidine
CAS 1353502-42-7C10H9N3OS
(4-Pyridin-4-ylpyrimidin-2-yl)methanamine chemical structure, C10H10N4, CAS 944898-41-3
(4-Pyridin-4-ylpyrimidin-2-yl)methanamine
CAS 944898-41-3C10H10N4
4-(Pyridin-4-yl)-2-(trifluoromethyl)pyrimidine chemical structure, C10H6F3N3, CAS 1269292-76-3
4-(Pyridin-4-yl)-2-(trifluoromethyl)pyrimidine
CAS 1269292-76-3C10H6F3N3
6-(Pyridin-4-yl)pyrimidin-4-amine chemical structure, C9H8N4, CAS 1192814-38-2
6-(Pyridin-4-yl)pyrimidin-4-amine
CAS 1192814-38-2C9H8N4
4-Isothiocyanato-6-(pyridin-4-yl)pyrimidine chemical structure, C10H6N4S, CAS 1192814-39-3
4-Isothiocyanato-6-(pyridin-4-yl)pyrimidine
CAS 1192814-39-3C10H6N4S
6-(2-Chloro-4-pyridinyl)-4-pyrimidinecarboxylic acid chemical structure, C10H6ClN3O2, CAS 1097254-47-1
6-(2-Chloro-4-pyridinyl)-4-pyrimidinecarboxylic acid
CAS 1097254-47-1C10H6ClN3O2