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Murcko scaffold

4-(Pyridin-4-yl)pyrimidine scaffold

92 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
92
With full pages
5
Scaffold SMILES

c1cc(-c2ccncn2)ccn1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-(Pyridin-4-yl)pyrimidine page
Murcko scaffold c1cc(-c2ccncn2)ccn1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 92 of 92 chemicals

Pyrimidine, 2-chloro-5-fluoro-4-(2-fluoro-4-pyridinyl)- chemical structure, C9H4ClF2N3, CAS 1453851-91-6
Pyrimidine, 2-chloro-5-fluoro-4-(2-fluoro-4-pyridinyl)-
CAS 1453851-91-6C9H4ClF2N3
4-(5-Methyl-4-pyrimidinyl)-3-pyridinamine chemical structure, C10H10N4, CAS 1613199-44-2
4-(5-Methyl-4-pyrimidinyl)-3-pyridinamine
CAS 1613199-44-2C10H10N4
2-[(3-Methoxypropyl)amino]-4-(pyridin-4-yl)pyrimidine-5-carboxylic acid chemical structure, C14H16N4O3, CAS 1775371-09-9
2-[(3-Methoxypropyl)amino]-4-(pyridin-4-yl)pyrimidine-5-carboxylic acid
CAS 1775371-09-9C14H16N4O3
6-(Pyridin-4-yl)-2-thioureido-4-(trifluoromethyl)pyrimidine chemical structure, C11H8F3N5S, CAS 2377235-74-8
6-(Pyridin-4-yl)-2-thioureido-4-(trifluoromethyl)pyrimidine
CAS 2377235-74-8C11H8F3N5S
N-[6-(Pyridin-4-yl)-4-(trifluoromethyl)pyrimidin-2-yl]glycine chemical structure, C12H9F3N4O2, CAS 1820710-65-3
N-[6-(Pyridin-4-yl)-4-(trifluoromethyl)pyrimidin-2-yl]glycine
CAS 1820710-65-3C12H9F3N4O2
2-Chloro-6-(pyridin-4-yl)-4-(trifluoromethyl)pyrimidine chemical structure, C10H5ClF3N3, CAS 1271475-68-3
2-Chloro-6-(pyridin-4-yl)-4-(trifluoromethyl)pyrimidine
CAS 1271475-68-3C10H5ClF3N3
2-Iodo-6-(pyridin-4-yl)-4-(trifluoromethyl)pyrimidine chemical structure, C10H5F3IN3, CAS 1820607-24-6
2-Iodo-6-(pyridin-4-yl)-4-(trifluoromethyl)pyrimidine
CAS 1820607-24-6C10H5F3IN3
6-(Pyridin-4-yl)-2-thiosemicarbazido-4-(trifluoromethyl)pyrimidine chemical structure, C11H9F3N6S, CAS 1820717-66-5
6-(Pyridin-4-yl)-2-thiosemicarbazido-4-(trifluoromethyl)pyrimidine
CAS 1820717-66-5C11H9F3N6S
2-Ethyl-4-(pyridin-4-yl)pyrimidine-5-carboxylic acid chemical structure, C12H11N3O2, CAS 1708080-58-3
2-Ethyl-4-(pyridin-4-yl)pyrimidine-5-carboxylic acid
CAS 1708080-58-3C12H11N3O2
2-(Diethylamino)-4-(pyridin-4-yl)pyrimidine-5-carboxylic acid chemical structure, C14H16N4O2, CAS 1713462-89-5
2-(Diethylamino)-4-(pyridin-4-yl)pyrimidine-5-carboxylic acid
CAS 1713462-89-5C14H16N4O2
4-Bromo-2-methyl-6-(pyridin-4-yl)pyrimidine chemical structure, C10H8BrN3, CAS 1412957-84-6
4-Bromo-2-methyl-6-(pyridin-4-yl)pyrimidine
CAS 1412957-84-6C10H8BrN3
4-Bromo-2-(iso-propyl)-6-(pyridin-4-yl)-pyrimidine chemical structure, C12H12BrN3, CAS 1412957-91-5
4-Bromo-2-(iso-propyl)-6-(pyridin-4-yl)-pyrimidine
CAS 1412957-91-5C12H12BrN3
2-Methyl-6-(pyridin-4-yl)pyrimidine-4-carbonitrile chemical structure, C11H8N4, CAS 1894671-11-4
2-Methyl-6-(pyridin-4-yl)pyrimidine-4-carbonitrile
CAS 1894671-11-4C11H8N4
2-Bromo-4-(pyridin-4-yl)-6-methylpyrimidine chemical structure, C10H8BrN3, CAS 1412954-50-7
2-Bromo-4-(pyridin-4-yl)-6-methylpyrimidine
CAS 1412954-50-7C10H8BrN3
6-(Pyridin-4-yl)pyrimidine-4-carbonitrile chemical structure, C10H6N4, CAS 2098031-62-8
6-(Pyridin-4-yl)pyrimidine-4-carbonitrile
CAS 2098031-62-8C10H6N4
2-Methyl-6-(pyridin-4-yl)pyrimidine-4-carboxylic acid chemical structure, C11H9N3O2, CAS 2092102-74-2
2-Methyl-6-(pyridin-4-yl)pyrimidine-4-carboxylic acid
CAS 2092102-74-2C11H9N3O2
Methyl 6-(pyridin-4-yl)pyrimidine-4-carboxylate chemical structure, C11H9N3O2, CAS 2097957-81-6
Methyl 6-(pyridin-4-yl)pyrimidine-4-carboxylate
CAS 2097957-81-6C11H9N3O2
Methyl 2-methyl-6-(pyridin-4-yl)pyrimidine-4-carboxylate chemical structure, C12H11N3O2, CAS 2098138-25-9
Methyl 2-methyl-6-(pyridin-4-yl)pyrimidine-4-carboxylate
CAS 2098138-25-9C12H11N3O2
Ethyl 6-(pyridin-4-yl)pyrimidine-4-carboxylate chemical structure, C12H11N3O2, CAS 2097958-49-9
Ethyl 6-(pyridin-4-yl)pyrimidine-4-carboxylate
CAS 2097958-49-9C12H11N3O2
4-(2-(tert-Butoxy)pyridin-4-yl)-2-(methylthio)pyrimidine chemical structure, C14H17N3OS, CAS 1817728-49-6
4-(2-(tert-Butoxy)pyridin-4-yl)-2-(methylthio)pyrimidine
CAS 1817728-49-6C14H17N3OS
2-Bromo-4-(pyridin-4-yl)-6-(iso-propyl)pyrimidine chemical structure, C12H12BrN3, CAS 1412961-60-4
2-Bromo-4-(pyridin-4-yl)-6-(iso-propyl)pyrimidine
CAS 1412961-60-4C12H12BrN3
2-Chloro-4-bromo-6-(4-pyridyl)pyrimidine chemical structure, C9H5BrClN3, CAS 1412956-40-1
2-Chloro-4-bromo-6-(4-pyridyl)pyrimidine
CAS 1412956-40-1C9H5BrClN3
2-Bromo-4-chloro-6-(4-pyridyl)pyrimidine chemical structure, C9H5BrClN3, CAS 1434127-94-2
2-Bromo-4-chloro-6-(4-pyridyl)pyrimidine
CAS 1434127-94-2C9H5BrClN3
4-(2-Bromopyridin-4-yl)-2,6-dichloropyrimidine chemical structure, C9H4BrCl2N3, CAS 2089977-00-2
4-(2-Bromopyridin-4-yl)-2,6-dichloropyrimidine
CAS 2089977-00-2C9H4BrCl2N3