CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 18 atoms

51 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
18
Chemicals
51
With full pages
13
Scaffold SMILES

C1=CC2(Cc3ccccc3N2)Oc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=CC2(Cc3ccccc3N2)Oc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 51 chemicals

1',3'-Dihydro-5'-methoxy-1',3',3'-trimethyl-6-nitrospiro(2H-1-benzopyran-2,2'-(2H)indole) chemical structure, C20H20N2O4, CAS 16331-96-7
1',3'-Dihydro-5'-methoxy-1',3',3'-trimethyl-6-nitrospiro(2H-1-benzopyran-2,2'-(2H)indole)
CAS 16331-96-7C20H20N2O4
Spiro[2H-1-benzopyran-2,2'-[2H]indole], 1',3'-dihydro-1',3',3'-trimethyl-6,8-dinitro- chemical structure, C19H17N3O5, CAS 20200-64-0
Spiro[2H-1-benzopyran-2,2'-[2H]indole], 1',3'-dihydro-1',3',3'-trimethyl-6,8-dinitro-
CAS 20200-64-0C19H17N3O5
Spiro(2H-1-benzopyran-2,2'-(2H)indol)-6-ol, 1',3'-dihydro-1',3',3'-trimethyl- chemical structure, C19H19NO2, CAS 23001-29-8
Spiro(2H-1-benzopyran-2,2'-(2H)indol)-6-ol, 1',3'-dihydro-1',3',3'-trimethyl-
CAS 23001-29-8C19H19NO2
1,3,3-Trimethylindolinobenzospiropyran chemical structure, C19H19NO, CAS 1485-92-3
1,3,3-Trimethylindolinobenzospiropyran
CAS 1485-92-3C19H19NO
1',3'-Dihydro-8-methoxy-1',3',3'-trimethyl-6-nitrospiro(2H-1-benzopyran-2,2'-(2H)indole) chemical structure, C20H20N2O4, CAS 1498-89-1
1',3'-Dihydro-8-methoxy-1',3',3'-trimethyl-6-nitrospiro(2H-1-benzopyran-2,2'-(2H)indole)
CAS 1498-89-1C20H20N2O4
1',3'-Dihydro-1',3',3'-trimethyl-6-nitrospiro(2H-1-benzopyran-2,2'-(2H)indole) chemical structure, C19H18N2O3, CAS 1498-88-0
1',3'-Dihydro-1',3',3'-trimethyl-6-nitrospiro(2H-1-benzopyran-2,2'-(2H)indole)
CAS 1498-88-0C19H18N2O3
Spiro[2H-1-benzopyran-2,2'-[2H]indole], 1',3'-dihydro-1',3',3'-trimethyl-8-nitro- chemical structure, C19H18N2O3, CAS 5150-50-5
Spiro[2H-1-benzopyran-2,2'-[2H]indole], 1',3'-dihydro-1',3',3'-trimethyl-8-nitro-
CAS 5150-50-5C19H18N2O3
1',3'-Dihydro-7-methoxy-1',3',3'-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2'-[2H]indole] chemical structure, C20H20N2O4, CAS 6587-80-0
1',3'-Dihydro-7-methoxy-1',3',3'-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2'-[2H]indole]
CAS 6587-80-0C20H20N2O4
1-(beta-Carboxyethyl)-3,3-dimethyl-6'-nitrospiro(indoline-2,2'-2H-benzopyran) chemical structure, C21H20N2O5, CAS 55779-26-5
1-(beta-Carboxyethyl)-3,3-dimethyl-6'-nitrospiro(indoline-2,2'-2H-benzopyran)
CAS 55779-26-5C21H20N2O5
5'-Chloro-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole] chemical structure, C16H11ClN2O3, CAS 26456-32-6
5'-Chloro-6-nitro-1',3'-dihydrospiro[chromene-2,2'-indole]
CAS 26456-32-6C16H11ClN2O3
3'-Hexadecyl-1',3'-dimethyl-6-nitrospiro[chromene-2,2'-indole] chemical structure, C34H48N2O3, CAS 60168-20-9
3'-Hexadecyl-1',3'-dimethyl-6-nitrospiro[chromene-2,2'-indole]
CAS 60168-20-9C34H48N2O3
Spiro(2H-1-benzopyran-2,2'-(2H)indole), 1'-hexadecyl-1',3'-dihydro-3',3'-dimethyl-8-nitro- chemical structure, C34H48N2O3, CAS 60168-18-5
Spiro(2H-1-benzopyran-2,2'-(2H)indole), 1'-hexadecyl-1',3'-dihydro-3',3'-dimethyl-8-nitro-
CAS 60168-18-5C34H48N2O3
1,3,3-Trimethylindolino-6'-bromobenzopyrylospiran chemical structure, C19H18BrNO, CAS 16650-14-9
1,3,3-Trimethylindolino-6'-bromobenzopyrylospiran
CAS 16650-14-9C19H18BrNO
RefChem:313985 chemical structure, C19H17BrN2O3, CAS 13034-70-3
RefChem:313985
CAS 13034-70-3C19H17BrN2O3
1'-Dodecyl-3',3'-dimethyl-6-nitrospiro[chromene-2,2'-indole] chemical structure, C30H40N2O3, CAS 87524-69-4
1'-Dodecyl-3',3'-dimethyl-6-nitrospiro[chromene-2,2'-indole]
CAS 87524-69-4C30H40N2O3
5'-Chloro-6-methoxy-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole] chemical structure, C20H20ClNO2, CAS 209059-33-6
5'-Chloro-6-methoxy-1',3',3'-trimethyl-1',3'-dihydrospiro[chromene-2,2'-indole]
CAS 209059-33-6C20H20ClNO2
6-Methoxy-1',3',3'-trimethylspiro[chromene-2,2'-indoline] chemical structure, C20H21NO2, CAS 20200-73-1
6-Methoxy-1',3',3'-trimethylspiro[chromene-2,2'-indoline]
CAS 20200-73-1C20H21NO2
1,3,3-Trimethylindolino-8'-methoxybenzopyrylospiran chemical structure, C20H21NO2, CAS 13433-31-3
1,3,3-Trimethylindolino-8'-methoxybenzopyrylospiran
CAS 13433-31-3C20H21NO2
6-Chloro-1',3',3'-trimethyl-8-nitrospiro[chromene-2,2'-indole] chemical structure, C19H17ClN2O3, CAS 6427-75-4
6-Chloro-1',3',3'-trimethyl-8-nitrospiro[chromene-2,2'-indole]
CAS 6427-75-4C19H17ClN2O3
2-(6-Bromo-3',3'-dimethylspiro[chromene-2,2'-indole]-1'-yl)ethanol chemical structure, C20H20BrNO2, CAS 101509-72-2
2-(6-Bromo-3',3'-dimethylspiro[chromene-2,2'-indole]-1'-yl)ethanol
CAS 101509-72-2C20H20BrNO2
1',3'-Dihydro-1',3',3'-trimethyl-5'-nitrospiro[2H-1-benzopyran-2,2'-[2H]indole] chemical structure, C19H18N2O3, CAS 80985-35-9
1',3'-Dihydro-1',3',3'-trimethyl-5'-nitrospiro[2H-1-benzopyran-2,2'-[2H]indole]
CAS 80985-35-9C19H18N2O3
2-(3',3'-Dimethyl-6-nitrospiro(1-benzopyran-2,2'-indol)-1'(3'H)-yl)ethan-1-ol chemical structure, C20H20N2O4, CAS 5475-99-0
2-(3',3'-Dimethyl-6-nitrospiro(1-benzopyran-2,2'-indol)-1'(3'H)-yl)ethan-1-ol
CAS 5475-99-0C20H20N2O4
1',3',3'-Trimethyl-6-nitro-7-propan-2-yloxyspiro[chromene-2,2'-indole] chemical structure, C22H24N2O4, CAS 5083-43-2
1',3',3'-Trimethyl-6-nitro-7-propan-2-yloxyspiro[chromene-2,2'-indole]
CAS 5083-43-2C22H24N2O4
3',3'-Dimethyl-6-nitro-1'-octyl-1',3'-dihydrospiro[chromene-2,2'-indole] chemical structure, C26H32N2O3, CAS 34756-29-1
3',3'-Dimethyl-6-nitro-1'-octyl-1',3'-dihydrospiro[chromene-2,2'-indole]
CAS 34756-29-1C26H32N2O3