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Murcko scaffold

1H-Pyrazolo[3,4-b]pyridin-4-ol scaffold

33 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
33
With full pages
6
Scaffold SMILES

O=c1cc[nH]c2[nH]ncc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1H-Pyrazolo[3,4-b]pyridin-4-ol page
Murcko scaffold O=c1cc[nH]c2[nH]ncc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

1,7-Dimethyl-4-oxo-1H,4H,7H-pyrazolo[3,4-b]pyridine-5-carboxylic acid chemical structure, C9H9N3O3, CAS 1798702-11-0
1,7-Dimethyl-4-oxo-1H,4H,7H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
CAS 1798702-11-0C9H9N3O3
1,3-Dimethyl-6-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-4-ol chemical structure, C9H8F3N3O, CAS 332867-83-1
1,3-Dimethyl-6-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-4-ol
CAS 332867-83-1C9H8F3N3O
1,6-Dimethyl-1H,4H,7H-pyrazolo(3,4-b)pyridin-4-one chemical structure, C8H9N3O, CAS 73810-84-1
1,6-Dimethyl-1H,4H,7H-pyrazolo(3,4-b)pyridin-4-one
CAS 73810-84-1C8H9N3O
6-Amino-1H-pyrazolo[3,4-b]pyridin-4(2H)-one chemical structure, C6H6N4O, CAS 35313-41-8
6-Amino-1H-pyrazolo[3,4-b]pyridin-4(2H)-one
CAS 35313-41-8C6H6N4O
1-Amino-6-chloro-3-methyl-7H-pyrazolo[5,4-b]pyridin-4-one chemical structure, C7H7ClN4O, CAS 78998-35-3
1-Amino-6-chloro-3-methyl-7H-pyrazolo[5,4-b]pyridin-4-one
CAS 78998-35-3C7H7ClN4O
4-Hydroxy-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid chemical structure, C8H7N3O3, CAS 37800-04-7
4-Hydroxy-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
CAS 37800-04-7C8H7N3O3
1-Ethyl-4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid chemical structure, C9H9N3O3, CAS 30720-05-9
1-Ethyl-4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid
CAS 30720-05-9C9H9N3O3
Ethyl 1-methyl-4-oxo-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C10H11N3O3, CAS 37799-86-3
Ethyl 1-methyl-4-oxo-4,7-dihydro-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 37799-86-3C10H11N3O3
3,6-Dimethyl-1-ethyl-1H-pyrazolo[3,4-b]pyridin-4-ol chemical structure, C10H13N3O, CAS 55139-30-5
3,6-Dimethyl-1-ethyl-1H-pyrazolo[3,4-b]pyridin-4-ol
CAS 55139-30-5C10H13N3O
1H-Pyrazolo[3,4-b]pyridin-4-ol chemical structure, C6H5N3O, CAS 31591-86-3
1H-Pyrazolo[3,4-b]pyridin-4-ol
CAS 31591-86-3C6H5N3O
1,3-Dimethyl-1H-pyrazolo[3,4-b]pyridin-4-ol chemical structure, C8H9N3O, CAS 1057670-30-0
1,3-Dimethyl-1H-pyrazolo[3,4-b]pyridin-4-ol
CAS 1057670-30-0C8H9N3O
1-Methyl-1H,4H,7H-pyrazolo[3,4-b]pyridin-4-one chemical structure, C7H7N3O, CAS 54738-76-0
1-Methyl-1H,4H,7H-pyrazolo[3,4-b]pyridin-4-one
CAS 54738-76-0C7H7N3O
Ethyl 1,6-diethyl-4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C13H17N3O3, CAS 1005418-88-1
Ethyl 1,6-diethyl-4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 1005418-88-1C13H17N3O3
4-Hydroxy-2-methyl-2H-pyrazolo[3,4-b]pyridine-5-carboxylic acid, ethyl ester chemical structure, C10H11N3O3, CAS 61627-37-0
4-Hydroxy-2-methyl-2H-pyrazolo[3,4-b]pyridine-5-carboxylic acid, ethyl ester
CAS 61627-37-0C10H11N3O3
Ethyl 1-ethyl-4-hydroxy-6-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C12H15N3O3, CAS 41095-06-1
Ethyl 1-ethyl-4-hydroxy-6-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 41095-06-1C12H15N3O3
1,3-Dimethyl-4-oxo-1H,4H,7H-pyrazolo(3,4-b)pyridine-6-carboxylic acid chemical structure, C9H9N3O3, CAS 1375474-42-2
1,3-Dimethyl-4-oxo-1H,4H,7H-pyrazolo(3,4-b)pyridine-6-carboxylic acid
CAS 1375474-42-2C9H9N3O3
Ethyl 4-hydroxy-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C11H13N3O3, CAS 19736-06-2
Ethyl 4-hydroxy-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 19736-06-2C11H13N3O3
3-Methyl-4-oxo-4,7-dihydro-1H-pyrazolo[3,4-B]pyridine-5-carboxylic acid ethyl ester chemical structure, C10H11N3O3, CAS 52744-83-9
3-Methyl-4-oxo-4,7-dihydro-1H-pyrazolo[3,4-B]pyridine-5-carboxylic acid ethyl ester
CAS 52744-83-9C10H11N3O3
Methyl 4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C8H7N3O3, CAS 1335053-55-8
Methyl 4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 1335053-55-8C8H7N3O3
4-Hydroxy-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile chemical structure, C9H8N4O, CAS 116835-14-4
4-Hydroxy-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile
CAS 116835-14-4C9H8N4O
4-Hydroxy-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid chemical structure, C7H5N3O3, CAS 1781790-67-7
4-Hydroxy-1H-pyrazolo[3,4-b]pyridine-6-carboxylic acid
CAS 1781790-67-7C7H5N3O3
4-Hydroxy-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile chemical structure, C8H6N4O, CAS 116835-13-3
4-Hydroxy-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile
CAS 116835-13-3C8H6N4O
Ethyl 4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylate chemical structure, C9H9N3O3, CAS 41094-96-6
Ethyl 4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
CAS 41094-96-6C9H9N3O3
6-Methyl-1H-pyrazolo[3,4-b]pyridin-4-ol chemical structure, C7H7N3O, CAS 17902-29-3
6-Methyl-1H-pyrazolo[3,4-b]pyridin-4-ol
CAS 17902-29-3C7H7N3O