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Murcko scaffold

Ring system with 1 ring and 9 atoms

45 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
9
Chemicals
45
With full pages
4
Scaffold SMILES

C=C1C(=O)OCOC1=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1C(=O)OCOC1=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

2,2-Dimethyl-5-(1-methylethylidene)-1,3-dioxane-4,6-dione chemical structure, C9H12O4, CAS 2231-66-5
2,2-Dimethyl-5-(1-methylethylidene)-1,3-dioxane-4,6-dione
CAS 2231-66-5C9H12O4
5-(Methoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C8H10O5, CAS 15568-85-1
5-(Methoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 15568-85-1C8H10O5
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]propanamide chemical structure, C10H13NO5, CAS 175728-08-2
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]propanamide
CAS 175728-08-2C10H13NO5
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]-2,2-dimethylpropanamide chemical structure, C12H17NO5, CAS 175728-10-6
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]-2,2-dimethylpropanamide
CAS 175728-10-6C12H17NO5
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]-3-methylbutanamide chemical structure, C12H17NO5, CAS 477885-86-2
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]-3-methylbutanamide
CAS 477885-86-2C12H17NO5
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]butanamide chemical structure, C11H15NO5, CAS 477885-89-5
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]butanamide
CAS 477885-89-5C11H15NO5
3-Amino-3-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)propanenitrile chemical structure, C9H10N2O4, CAS 338406-49-8
3-Amino-3-(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)propanenitrile
CAS 338406-49-8C9H10N2O4
2,2-Dimethyl-5-(((1-methylethyl)thio)methylene)-1,3-dioxane-4,6-dione chemical structure, C10H14O4S, CAS 128889-75-8
2,2-Dimethyl-5-(((1-methylethyl)thio)methylene)-1,3-dioxane-4,6-dione
CAS 128889-75-8C10H14O4S
5-[(tert-Butylsulfanyl)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C11H16O4S, CAS 477866-60-7
5-[(tert-Butylsulfanyl)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 477866-60-7C11H16O4S
1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-[1-(methylthio)ethylidene]- chemical structure, C9H12O4S, CAS 112182-59-9
1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-[1-(methylthio)ethylidene]-
CAS 112182-59-9C9H12O4S
5-[Bis(methylsulfanyl)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C9H12O4S2, CAS 100981-05-3
5-[Bis(methylsulfanyl)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 100981-05-3C9H12O4S2
5-(Dimethylaminomethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C9H13NO4, CAS 75039-60-0
5-(Dimethylaminomethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 75039-60-0C9H13NO4
5-(Aminomethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C7H9NO4, CAS 15568-88-4
5-(Aminomethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 15568-88-4C7H9NO4
1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-[(methylamino)methylene]- chemical structure, C8H11NO4, CAS 111286-54-5
1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-[(methylamino)methylene]-
CAS 111286-54-5C8H11NO4
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]pentanamide chemical structure, C12H17NO5, CAS 477885-75-9
N-[(2,2-Dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)methyl]pentanamide
CAS 477885-75-9C12H17NO5
5-(1-Aminoethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C8H11NO4, CAS 77570-17-3
5-(1-Aminoethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 77570-17-3C8H11NO4
5-(Ethoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C9H12O5, CAS 15568-86-2
5-(Ethoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 15568-86-2C9H12O5
1,3-Dioxane-4,6-dione, 5-(1-ethoxyethylidene)-2,2-dimethyl- chemical structure, C10H14O5, CAS 138370-97-5
1,3-Dioxane-4,6-dione, 5-(1-ethoxyethylidene)-2,2-dimethyl-
CAS 138370-97-5C10H14O5
5-(1-Methoxyethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C9H12O5, CAS 121781-82-6
5-(1-Methoxyethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 121781-82-6C9H12O5
1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-(2-methylpropylidene)- chemical structure, C10H14O4, CAS 15795-47-8
1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-(2-methylpropylidene)-
CAS 15795-47-8C10H14O4
5-(Hydroxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C7H8O5, CAS 15568-87-3
5-(Hydroxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 15568-87-3C7H8O5
5-(2,2-Dimethylpropylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione chemical structure, C11H16O4, CAS 15579-89-2
5-(2,2-Dimethylpropylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione
CAS 15579-89-2C11H16O4
1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-[1-(methylthio)propylidene]- chemical structure, C10H14O4S, CAS 112182-60-2
1,3-Dioxane-4,6-dione, 2,2-dimethyl-5-[1-(methylthio)propylidene]-
CAS 112182-60-2C10H14O4S
2,2-Dimethyl-5-methylene-1,3-dioxane-4,6-dione chemical structure, C7H8O4, CAS 23340-26-3
2,2-Dimethyl-5-methylene-1,3-dioxane-4,6-dione
CAS 23340-26-3C7H8O4