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Murcko scaffold

Ring system with 4 rings and 26 atoms

11 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
11
With full pages
1
Scaffold SMILES

O=C1NC(=O)C(Cc2ccc(OCC3CCc4ccccc4O3)cc2)S1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC(=O)C(Cc2ccc(OCC3CCc4ccccc4O3)cc2)S1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Troglitazone chemical structure, C24H27NO5S, CAS 97322-87-7
Troglitazone
CAS 97322-87-7C24H27NO5S
2,4-Thiazolidinedione, 5-((4-((7-(1,1-dimethylethyl)-3,4-dihydro-6-hydroxy-2-methyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)- chemical structure, C25H29NO5S, CAS 97323-07-4
2,4-Thiazolidinedione, 5-((4-((7-(1,1-dimethylethyl)-3,4-dihydro-6-hydroxy-2-methyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-
CAS 97323-07-4C25H29NO5S
2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2-methyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)- chemical structure, C21H21NO5S, CAS 137786-86-8
2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-2-methyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-
CAS 137786-86-8C21H21NO5S
Carbonic acid, 2-((4-((2,4-dioxo-5-thiazolidinyl)methyl)phenoxy)methyl)-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-yl ethyl ester chemical structure, C27H31NO7S, CAS 137786-87-9
Carbonic acid, 2-((4-((2,4-dioxo-5-thiazolidinyl)methyl)phenoxy)methyl)-3,4-dihydro-2,5,7,8-tetramethyl-2H-1-benzopyran-6-yl ethyl ester
CAS 137786-87-9C27H31NO7S
(5R)-5-(4-{[(2R)-6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl]methoxy}benzyl)-1,3-thiazolidine-2,4-dione chemical structure, C24H27NO5S, CAS 640275-14-5
(5R)-5-(4-{[(2R)-6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl]methoxy}benzyl)-1,3-thiazolidine-2,4-dione
CAS 640275-14-5C24H27NO5S
2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-5,7,8-trimethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)- chemical structure, C23H25NO5S, CAS 97322-96-8
2,4-Thiazolidinedione, 5-((4-((3,4-dihydro-6-hydroxy-5,7,8-trimethyl-2H-1-benzopyran-2-yl)methoxy)phenyl)methyl)-
CAS 97322-96-8C23H25NO5S
Troglitazone sulfate sodium chemical structure, C24H26NNaO8S2, CAS 110765-08-7
Troglitazone sulfate sodium
CAS 110765-08-7C24H26NNaO8S2
Troglitazone, (2S,5R)-(+-)- chemical structure, C24H27NO5S, CAS 640275-16-7
Troglitazone, (2S,5R)-(+-)-
CAS 640275-16-7C24H27NO5S
Troglitazone sulfate ammonium salt chemical structure, C24H30N2O8S2, CAS 107187-86-0
Troglitazone sulfate ammonium salt
CAS 107187-86-0C24H30N2O8S2
Troglitazone-d4 chemical structure, C24H27NO5S, CAS 2749370-85-0
Troglitazone-d4
CAS 2749370-85-0C24H27NO5S
Troglitazone sulfate pyridinium salt chemical structure, C29H32N2O8S2, CAS 110795-65-8
Troglitazone sulfate pyridinium salt
CAS 110795-65-8C29H32N2O8S2