Murcko scaffold
Benzene, cyclobutyl- scaffold
6,426 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 10
- Chemicals
- 6,426
- With full pages
- 298
Scaffold SMILES
c1ccc(C2CCC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 6,426 chemicals
Sibutramine
CAS 106650-56-0C17H26ClN
2-(4-Methoxyphenyl)cyclobutan-1-amine--hydrogen chloride (1/1)
CAS 15812-48-3C11H16ClNO
2-(4-Methoxyphenyl)cyclobutan-1-amine
CAS 15812-47-2C11H15NO
(1s,3s)-3-Phenylcyclobutane-1-carboxylic acid
CAS 16204-48-1C11H12O2
Sibutramine hydrochloride
CAS 84485-00-7C17H27Cl2N
Meridia
CAS 125494-59-9C17H29Cl2NO
1-Phenylcyclobutanecarbonitrile
CAS 14377-68-5C11H11N
1-(4-Chlorophenyl)cyclobutanecarbonitrile
CAS 28049-61-8C11H10ClN
Didesmethylsibutramine hydrochloride
CAS 84484-78-6C15H23Cl2N
Didesmethylsibutramine
CAS 84467-54-9C15H22ClN
1-Phenylcyclobutan-1-ol
CAS 935-64-8C10H12O
Benzene, cyclobutyl-
CAS 4392-30-7C10H12
(1-Methylcyclobutyl)benzene
CAS 7306-05-0C11H14
2-(2,5-Dimethoxy-4-methylphenyl)cyclobutylamine
CAS 90791-14-3C13H19NO2
2-(2,4,5-Trimethoxyphenyl)cyclobutylamine
CAS 90791-20-1C13H19NO3
1-Phenylcyclobutylamine
CAS 17380-77-7C10H13N
(1-Methoxycyclobutyl)benzene
CAS 1007-70-1C11H14O
1-Phenylcyclobutanecarboxylic acid
CAS 37828-19-6C11H12O2
4-Cyclobutylbenzoic acid
CAS 3158-70-1C11H12O2
2-Phenylcyclobutane-1,1-dicarboxylic acid
CAS 91963-65-4C12H12O4
3-Phenylcyclobutane-1,1-dicarboxylic acid
CAS 1570-97-4C12H12O4
2,2,3,3-Tetramethoxy-4-phenyl-cyclobutane-1,1-dicarbonitrile
CAS 56069-52-4C16H18N2O4
2,2,3,3-Tetramethoxy-4-(4-nitrophenyl)cyclobutane-1,1-dicarbonitrile
CAS 56069-51-3C16H17N3O6
4-(4-Chlorophenyl)-2,2,3,3-tetramethoxycyclobutane-1,1-dicarbonitrile
CAS 56069-79-5C16H17ClN2O4
- 2,2,3,3-Tetramethoxy-4-(4-methoxyphenyl)cyclobutane-1,1-dicarbonitrile56069-53-5C17H20N2O5
- Ethyl 1-cyano-2,2,3,3-tetramethoxy-4-phenyl-cyclobutane-1-carboxylate56069-45-5C18H23NO6
- 1-Nitro-4-(2,2,3,3-tetramethoxy-4-nitrocyclobutyl)benzene88460-08-6C14H18N2O8
- 3-Phenylcyclobutan-1-amine hydrochloride1807916-62-6C10H14ClN
- 3-Phenylcyclobutan-1-amine90874-41-2C10H13N
- 4-(1-Methylcyclobutyl)phenol91876-30-1C11H14O
- 2 suppliers1-(p-Chlorophenyl)cyclobutanecarboxylic acid50921-39-6C11H11ClO2
- 1-(4-Fluorophenyl)cyclobutan-1-ol339365-53-6C10H11FO
- 1-(3-Chlorophenyl)cyclobutanecarboxylic acid151157-55-0C11H11ClO2
- (+)-Sibutramine154752-44-0C17H26ClN
- 1-(3-Chlorophenyl)cyclobutanamine158943-22-7C10H12ClN
- (-)-Sibutramine153341-22-1C17H26ClN
- 2-Chloro-1-[3-methyl-3-(2,4,6-trimethylphenyl)cyclobutyl]ethanone331415-58-8C16H21ClO
- Methyl 3-(1-(4-chlorophenyl)cyclobutane-1-carboxamido)propanoate851457-41-5C15H18ClNO3
- 2,2,3,3-Tetraethoxy-4-(4-methoxyphenyl)cyclobutane-1,1-dicarbonitrile6435-87-6C21H28N2O5
- 2-(2-Cyclobutylphenoxy)-N-hydroxypropanimidamide--hydrogen chloride (1/1)81721-02-0C13H19ClN2O2
- (2-Cyclobutylphenoxy)-N-hydroxyethanimidamide--hydrogen chloride (1/1)81721-03-1C12H17ClN2O2
- (-)-Didesmethylsibutramine229639-57-0C15H22ClN
- 1-(4-Chlorophenyl)-3-hydroxycyclobutane-1-carbonitrile485828-45-3C11H10ClNO
- Methanamine, N-[[1-(4-chlorophenyl)cyclobutyl]methylene]-259729-89-0C12H14ClN
- (R)-Desmethylsibutramine hydrochloride259731-40-3C16H25Cl2N
- R-(+)-Mono-desmethylsibutramine229639-54-7C16H24ClN
- (AlphaS)-1-(4-chlorophenyl)-N-methyl-alpha-(2-methylpropyl)cyclobutanemethanamine229639-55-8C16H24ClN
- Didesmethylsibutramine hydrochloride, (R)-262854-35-3C15H23Cl2N